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Glumetza (Metformin Hydrochloride ER) Shopper Approved

Prescription Prescription Required FormationFormulation: ER Tablet

Glumetza

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Prescription Prescription Required FormationFormulation: ER Tablet

Metformin Hydrochloride ER

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Glumetza contains the active ingredient metformin hydrochloride extended-release (ER). It is a prescription medication used to help control high blood sugar in adults with type 2 diabetes mellitus.

It is usually used together with a healthy diet, regular physical activity, and other parts of a diabetes treatment plan.

Type 2 Diabetes

Glumetza is used to improve glycemic control, which means helping keep blood sugar within a healthier range.

Type 2 diabetes occurs when the body does not use insulin effectively or does not make enough insulin to control blood sugar properly. This can cause glucose to build up in the bloodstream.

How Glumetza Works

Glumetza belongs to a group of medicines called biguanides.

Metformin lowers blood sugar mainly by reducing the amount of glucose made by the liver and helping the body’s tissues respond better to insulin.

Reducing Glucose Production by the Liver

The liver normally releases glucose into the bloodstream between meals.

In people with type 2 diabetes, the liver may release too much glucose. Glumetza helps reduce this excess production, which can lower blood sugar levels.

Improving Insulin Sensitivity

Glumetza also helps the body’s muscle and other tissues use insulin more effectively.

This allows glucose to move from the bloodstream into the cells, where it can be used for energy.

Extended-Release Formulation

The ER in Glumetza means extended-release.

The tablet is designed to release metformin gradually over several hours. This allows for longer-lasting blood sugar control and may make the medication easier to tolerate for some people.

Effect on Blood Sugar and A1C

When taken regularly, Glumetza can help lower both fasting blood sugar and overall average blood sugar levels.

Over time, this may also lower your A1C, which reflects your average blood sugar over the previous two to three months.

Glumetza Does Not Cure Diabetes

Glumetza does not cure type 2 diabetes.

Instead, it helps manage blood sugar over the long term and reduce the risk of complications associated with poorly controlled diabetes.

Diet and Exercise Are Still Important

Glumetza works best when combined with a suitable diet and exercise plan.

Medication helps control blood sugar, but it does not replace healthy eating, regular physical activity, or other recommendations from your healthcare provider.

Regular Monitoring

Your healthcare provider may monitor your blood sugar, A1C, kidney function, and overall response to treatment while you are taking Glumetza.

These results help determine whether the medication is working effectively and whether your dose needs to be adjusted.

Glumetza is an extended-release metformin tablet that is taken by mouth, usually once daily with the evening meal. Taking it with food helps reduce stomach-related side effects such as nausea, diarrhea, and abdominal discomfort.

Swallow the Tablet Whole

Swallow Glumetza whole with water.

Do not crush, cut, chew, or split the tablet. Glumetza is designed to release metformin slowly over time, and damaging the tablet can interfere with this extended-release system.

Usual Starting Dose

The recommended starting dose of Glumetza is 500 mg once daily with the evening meal.

This is different from some immediate-release metformin dosing schedules, which may be taken more than once a day.

Dose Increases

If additional blood sugar control is needed and the medication is well tolerated, your healthcare provider may increase the dose by 500 mg every 1 to 2 weeks.

Increasing the dose gradually can help reduce gastrointestinal side effects.

Maximum Daily Dose

The maximum recommended dose of Glumetza is 2,000 mg once daily with the evening meal.

Do not increase your dose on your own, even if your blood sugar remains above your target range.

How Your Dose Is Chosen

Your healthcare provider will consider your blood sugar levels, kidney function, side effects, other medications, and overall response to treatment when deciding on your dose.

The goal is to find the lowest dose that provides adequate blood sugar control while remaining well tolerated.

Take Glumetza Consistently

Try to take Glumetza at about the same time every evening with your meal.

Taking it consistently can help improve blood sugar control and make missed doses less likely.

If You Miss a Dose

If you forget a dose, do not take two doses on the same day to make up for it.

Skip the missed dose and take your next dose at the usual time with your next evening meal.

Do Not Stop Glumetza on Your Own

Do not stop taking Glumetza or change your dose without speaking with your healthcare provider.

Stopping treatment may cause your blood sugar to rise and make your diabetes more difficult to control.

Kidney Function Is Important

Metformin is removed from the body mainly through the kidneys.

Your healthcare provider should check your kidney function before starting Glumetza and periodically during treatment. Glumetza should not be used in people with severely reduced kidney function.

Regular Blood Sugar Monitoring

Your healthcare provider may monitor your blood glucose and A1C levels to determine how well Glumetza is working.

These results can help guide future dose adjustments.

Getting the Best Results

Take Glumetza once daily with your evening meal, swallow the tablet whole, and follow your prescribed dose carefully.

The dosing information in the original text stating 500 mg twice daily or 850 mg once daily with a maximum of 2,550 mg per day applies more closely to some immediate-release metformin regimens and is not the recommended dosing for Glumetza extended-release. Current Glumetza labeling recommends starting at 500 mg once daily and increasing as needed up to 2,000 mg once daily.

Common Side Effects of Glumetza (Metformin Hydrochloride ER):

  • A metallic taste in the mouth
  • Flatulence
  • Headache
  • Muscle pain
  • Nausea
  • Stomach upset
  • Vomiting
  • Weakness

Serious Side Effects of Glumetza (Metformin Hydrochloride ER):

  • Persistent vomiting
  • Seizure
  • Severe abdominal pain
  • Symptoms of high blood sugar or hyperglycemia (increased urination, thirst, confusion, flushing, rapid breathing, and fruity breath odor)
  • Symptoms of low blood sugar or hypoglycemia (shaking, sudden sweating, fast heartbeat, dizziness, blurred vision, tingling sensation)

Glumetza (Metformin Hydrochloride ER) is available in the following forms and strength:

Glumetza: ER Tablet

  • 500 mg
  • 1000 mg

Metformin Hydrochloride ER: ER Tablet

  • 1000 mg

Lactic Acidosis

Glumetza can rarely cause lactic acidosis, a serious buildup of lactic acid in the blood.

The risk is higher in people with significant kidney problems, severe liver disease, certain heart conditions, dehydration, or heavy alcohol use.

Seek urgent medical attention if you develop symptoms such as severe weakness, unusual tiredness, muscle pain, trouble breathing, dizziness, nausea, vomiting, or abdominal discomfort.

Low Blood Sugar

Glumetza by itself usually does not cause hypoglycemia, or low blood sugar.

However, low blood sugar can occur if Glumetza is taken with other diabetes medicines such as insulin or sulfonylureas.

Symptoms may include sweating, shakiness, hunger, dizziness, weakness, or confusion.

Vitamin B12 Deficiency

Long-term use of metformin can lower vitamin B12 levels in some people.

A deficiency may lead to anemia, numbness, tingling, weakness, or other nerve-related symptoms.

Your healthcare provider may check your vitamin B12 level periodically, especially if you have symptoms or other risk factors.

Kidney Problems

Glumetza is removed from the body mainly through the kidneys.

If kidney function is reduced, metformin can build up in the body and increase the risk of lactic acidosis.

Your healthcare provider may check your kidney function before treatment and regularly afterward. Glumetza may need to be stopped if kidney function becomes too low.

Liver Problems

Tell your healthcare provider if you have liver disease.

Severe liver problems can increase the risk of lactic acidosis because the liver helps process lactate.

Your healthcare provider may recommend a different treatment if your liver function is significantly impaired.

Iodinated Contrast for Imaging Tests

Some CT scans, angiograms, and other imaging procedures use iodinated contrast dye.

In certain situations, this contrast can temporarily affect kidney function and increase the risk of metformin buildup.

Your healthcare provider may tell you to temporarily stop Glumetza before or at the time of the procedure and restart it only after your kidney function has been checked.

Surgery and Medical Procedures

You may need to temporarily stop Glumetza before major surgery or certain medical procedures, especially if you will not be eating normally or may become dehydrated.

Always tell your healthcare team that you take metformin before a planned procedure.

Older Adults

Older adults can use Glumetza, but kidney function should be monitored carefully because kidney function may decline with age.

The main concern is not age alone, but whether the kidneys can remove metformin safely.

Use in Children

The safety and effectiveness of Glumetza have not been established in patients under 18 years of age.

A pediatric healthcare provider should determine the most appropriate diabetes treatment for children or adolescents.

Drug Interactions

Glumetza can interact with certain medications.

Some medicines may affect blood sugar levels, kidney function, or the amount of metformin in the body.

Tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and supplements you use.

Regular Monitoring

While taking Glumetza, your healthcare provider may monitor your blood sugar, A1C, kidney function, and vitamin B12 levels.

Regular follow-up helps make sure the medication remains safe and effective.

Can I take Glumetza without a meal?

Glumetza is best taken with food, usually with the evening meal. Taking it with food can help reduce stomach-related side effects such as nausea, diarrhea, gas, or abdominal discomfort.

How many times a day should I take Glumetza?

Glumetza is an extended-release form of metformin and is usually taken once daily with the evening meal. Other metformin formulations may be taken once or multiple times a day, so follow the instructions for the exact product prescribed to you.

Does Glumetza cause weight gain?

Glumetza is not usually associated with weight gain. Some people taking metformin may lose a small amount of weight, although the response varies from person to person.

Can people with heart problems take Glumetza?

Some people with heart conditions can take Glumetza, but your healthcare provider should review your condition first. Extra caution may be needed if you have unstable or severe heart failure, because conditions that reduce oxygen delivery to the body can increase the risk of lactic acidosis. Tell your healthcare provider about any history of heart failure, chest pain, shortness of breath, or other significant heart problems before starting Glumetza.

REVIEWS

Additional Information Book
Generic name:

Metformin Hydrochloride ER

Formulation:

ER Tablet

Strength(s):

500mg, 1000mg

Quantities Available:

90, 100

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Glumetza can I order at once from a Canadian pharmacy?

When ordering Glumetza (metformin hydrochloride ER) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Glumetza is commonly prescribed in dosages such as 500 mg or 1000 mg, taken once daily with the evening meal. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).

Do you sell metformin hydrochloride ER?

Yes, we sell metformin hydrochloride ER on our website. You can enjoy low prices when you order through us. To purchase metformin hydrochloride ER, you will need a valid prescription from your healthcare provider, as we require this to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it securely through your online account.

Do you offer shipping of Glumetza (metformin hydrochloride ER) to the United States?

Yes, we ship Glumetza (metformin hydrochloride ER) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Glumetza (Metformin Hydrochloride ER). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Glumetza (Metformin Hydrochloride ER).