Epiduo Gel (Adapalene Benzoyl Peroxide)

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Epiduo Gel Brand
Dosage Quantity & Price
Adapalene Benzoyl Peroxide (Generic alternate to Epiduo Gel) Generic

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Table of contents:

Epiduo Gel is a prescription medication used for the topical treatment of acne vulgaris. Epiduo Gel is a once-daily topical treatment for acne. It contains a combination of Adapalene and Benzoyl Peroxide. Adapalene and Benzoyl Peroxide work together to treat acne and help prevent new breakouts.

Benzoyl Peroxide has an antibacterial effect, and it also has a mild drying effect, which helps to control blackheads and whiteheads. Adapalene helps to regulate skin cell turnover and reduce inflammation, while Benzoyl Peroxide reduces the amount of acne-causing bacteria on the skin.

Uses and Dosage

Epiduo Gel is applied once a day, typically in the evening, to the affected areas of the skin. If excessive irritation or sensitivity occurs, a healthcare provider should be consulted to determine whether to discontinue use or adjust the frequency of application.

To use Epiduo Gel, follow these steps:

  1. Wash your hands thoroughly before applying the gel.
  2. Gently clean the affected area with a mild or soapless cleanser and pat dry.
  3. Apply a thin layer of Epiduo Gel to the affected area and rub it in gently.
  4. Avoid getting the gel in your eyes, mouth, or nose.
  5. Wash your hands again after applying the gel.
  6. Apply Epiduo Gel once a day, in the evening.
  7. Use Epiduo Gel regularly to see the best results.

The dosage of Epiduo Gel is to apply a thin film to the affected areas of the face and/or trunk once daily after washing, using a pea-sized amount for each area of the face. The Epiduo Gel prescribing information does not recommend using larger amounts or more frequently than recommended. Follow the instructions provided by your healthcare provider and read the medication label carefully for specific dosage and usage instructions.

Side effect

Common Side Effects of Epiduo Gel (Adapalene Benzoyl Peroxide):

  • Dryness
  • Itching
  • Mild burning
  • Peeling
  • Scaling
  • Skin redness
  • Stinging
  • Swelling
  • Worsening of acne during the first 4 weeks

Serious Side Effects of Epiduo Gel (Adapalene Benzoyl Peroxide):

  • Difficulty breathing
  • Hives
  • Itching
  • Lightheadedness
  • Other skin irritation
  • Sever redness or swelling of treated skin
  • Severe burning or stinging
  • Severe dryness
  • Swelling of your face, lips, tongue, or throat

Form and strength

Epiduo Gel (Adapalene Benzoyl Peroxide) is available in the following forms and strength:

Epiduo Gel: Gel

  • 0.1/2.5%


  • Epiduo Gel should be used with caution in patients with sensitive skin or a history of skin irritation.
  • It may cause dryness, redness, peeling, burning, stinging, scaling, swelling, itching, or other side effects, and patients should be advised to report any symptoms to their healthcare provider.
  • It should not be applied to broken or damaged skin or used alongside other topical acne medications unless directed to do so by a healthcare provider.
  • Patients should avoid exposure to sunlight and UV light, as this medication may increase the likelihood of sunburn.
  • It should be used with caution during pregnancy and nursing, as there is limited data on the safety of adapalene and benzoyl peroxide in these populations.
  • Patients with eczema or seborrheic dermatitis should use Epiduo Gel with caution, as it may exacerbate these conditions.
  • If excessive irritation or sensitivity occurs, a healthcare provider should be consulted to determine whether to discontinue use or adjust the frequency of application.
  • Patients should avoid using harsh or drying soaps, shampoos, or cosmetics while using Epiduo Gel.
  • Patients with a history of allergies or hypersensitivity to adapalene or benzoyl peroxide should not use this medication.

Frequently Asked Questions (FAQ)

How is Epiduo Gel used?

Epiduo Gel is applied topically once daily to the affected area(s) of the skin.

Is Epiduo Gel safe?

Like all medications, Epiduo Gel may cause side effects. Some of the most common side effects include dryness, redness, and peeling. Talk to your healthcare provider if you have concerns about the safety of Epiduo Gel.

Is Epiduo Gel available over the counter?

No, Epiduo Gel is a prescription medication and is only available with a doctor's prescription.


It's important to purchase Epiduo Gel from verified Canadian pharmacy.

Additional information

Generic name:

Adapalene Benzoyl Peroxide





Quantities Available:



Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Epiduo Gel (Adapalene Benzoyl Peroxide). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Epiduo Gel (Adapalene Benzoyl Peroxide).