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DDAVP Nasal Spray is a prescription medicine used to treat the symptoms of Diabetes Insipidus. Diabetes insipidus is a condition characterized by excessive thirst and excretion of large volumes of dilute urine. DDAVP Nasal Spray contains the active ingredient Desmopressin Acetate, which is a synthetic analogue of the natural hormone vasopressin. It works by replacing vasopressin, a hormone that is normally produced in the body to help balance the amount of water and salt.
Desmopressin Acetate Nasal Spray can be indicated as antidiuretic replacement therapy in the management of central cranial diabetes insipidus. It is also used to stop some types of bleeding in people with hemophilia (condition in which the blood does not clot normally) and von Willebrand's disease (a bleeding disorder) with certain blood levels.
Use and Dosage
DDAVP Nasal Spray (Desmopressin) is available as a liquid administered via a rhinal tube or nasal spray. It is typically used one to three times a day.
- If it is being used to treat hemophilia or von Willebrand's disease, one to two sprays are given each day.
- If it is being used prior to surgery, it is given two hours before the procedure.
- When it is used to treat frequent nighttime urination, one spray is usually given in either the left or right nostril 30 minutes before bedtime.
Use desmopressin nasal at the same time every day as directed by a doctor. Be sure to follow the prescription label instructions carefully and ask a healthcare provider to explain anything unclear. Do not use nasal desmopressin more or less frequently than prescribed by a doctor.
Common Side Effects of DDAVP Nasal Spray (Desmopressin):
- Back pain
- Discomfort in your nose
- Eye itching and
- Flushing (warmth redness or tingly feeling)
- Increased blood pressure
- Increased sensitivity to light
- Sinus pain
- Sleep problems (insomnia)
- Sore throat
- Stuffy nose
Serious Side Effects of DDAVP Nasal Spray (Desmopressin):
- Difficulty breathing
- Loss of appetite
- Muscle pain or weakness
- Rapid weight gain
- Runny or stuffy nose and
- Sinus congestion
- Swelling in your feet or ankles
- Swelling of your face lips tongue or throat
Forms and Strength
DDAVP Nasal Spray (Desmopressin) is available in the following forms and strength:
DDAVP Nasal Spray: Nasal Spray
Desmopressin: Nasal Spray
- Water intoxication: DDAVP Nasal Spray can lead to water retention and potentially result in water intoxication. This can cause symptoms such as headache, nausea, vomiting, seizures, and in severe cases, even coma.
- Hyponatremia: DDAVP Nasal Spray can also lower the level of sodium in the blood, which can cause symptoms such as headaches, confusion, seizures, and in severe cases, even coma.
- Fluid intake restriction: Use in infants and children may require careful fluid intake restriction to prevent hyponatremia and water intoxication.
- Cardiovascular disease: Use with caution in patients with a history of cardiovascular disease, as DDAVP Nasal Spray can cause increased blood pressure and fluid retention.
- Renal impairment: DDAVP Nasal Spray should be used with caution in patients with renal impairment, as it may increase the risk of water intoxication and hyponatremia.
- Allergic reactions: Use with caution in patients who have had allergic reactions to desmopressin or any of its components.
- Fluid and Electrolyte Imbalance: DDAVP Nasal Spray can cause imbalances in fluid and electrolytes, which can be especially harmful to patients with conditions such as heart failure or kidney disease.
- Pregnancy and breastfeeding: Use of DDAVP Nasal Spray in pregnancy and breastfeeding should be discussed with a doctor, as the potential risks and benefits should be carefully evaluated.
- Drug interactions: DDAVP Nasal Spray may interact with other medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), which can increase the risk of bleeding.
Frequently Asked Questions (FAQ)
How long does it take for DDAVP nasal spray to work?
DDAVP nasal spray typically starts working within 30 minutes to an hour after administration.
Can DDAVP nasal spray be used in children?
Yes, DDAVP nasal spray can be used in children, but the dose and frequency of administration may be different than in adults. It should be used with caution in children with a history of seizures or low blood sodium levels.
How should DDAVP nasal spray be stored?
DDAVP nasal spray should be stored at room temperature (between 68°F and 77°F) and away from light and moisture. It should also be kept out of reach of children.
Can DDAVP nasal spray be habit-forming?
No, DDAVP nasal spray is not known to be habit-forming.
It's important to purchase DDAVP Nasal Spray from verified Canadian pharmacy.