Indications
Coumadin (active ingredient: warfarin) is a prescription medication indicated for the following:
- Prevention of Thromboembolic Events: Coumadin is used to prevent and treat thromboembolic disorders such as deep vein thrombosis (DVT) and pulmonary embolism (PE).
- Atrial Fibrillation: It is indicated to reduce the risk of stroke and systemic embolism in patients with atrial fibrillation.
- Mechanical and Bioprosthetic Heart Valves: Coumadin is prescribed to prevent thromboembolism in patients with mechanical and bioprosthetic heart valves.
- Post-Myocardial Infarction: It is used as an adjunct in the treatment of patients after myocardial infarction to reduce the risk of recurrent myocardial infarction and thromboembolic events.
- Other Conditions: Coumadin may also be used in other conditions where there is a risk of thrombosis and embolism as deemed appropriate by a healthcare provider.
Coumadin belongs to a class of drugs known as anticoagulants (commonly referred to as blood thinners), which work by inhibiting the synthesis of vitamin K-dependent clotting factors, thereby preventing the formation of harmful clots in the blood vessels.
Uses and Dosage
Coumadin is an oral anticoagulant medication that comes in the form of a tablet. It is usually taken once a day, with or without food, as directed by your doctor or other healthcare professional. It is particularly important to take Coumadin exactly as directed, as taking more than the prescribed amount can lead to serious side effects. Do not increase the dose, take it more frequently, or stop using it unless instructed by your doctor.
The recommended dosage of Coumadin (warfarin) tablets for prevention or treatment of blood clots is 2 to 5 milligrams (mg) as a single dose once per day. Your doctor may adjust the dose if needed, but it is usually not more than 10 mg per day.
Side Effects
Common Side Effects of Coumadin:
- Bloating
- Gas
- Loss of appetite
- Nausea
- Stomach pain
Serious Side Effects of Warfarin:
- Chest pain
- Confusion
- Difficulty swallowing
- Fainting
- Painful, red/purplish patches on the skin
- Persistent vomiting
- Severe abdominal pain
- Severe headache
- Shortness of breath
- Vision changes
- Weakness on one side of the body
Form and Strength
Coumadin (Warfarin) is available in the following forms and strength:
Coumadin: Tablet
- 1 mg
- 2 mg
- 5 mg
Warfarin: Tablet
- 1 mg
- 2 mg
- 2.5 mg
- 3 mg
- 4 mg
- 5 mg
- 6 mg
- 7.5 mg
- 10 mg
Caution
- Let your doctor or pharmacist know if you are allergic to warfarin or any other medication, as this product may contain inactive ingredients that can cause allergic reactions or other issues. Be sure to speak to your pharmacist for more information.
- Before using Warfarin, tell your doctor or pharmacist your medical history, especially of blood disorders, bleeding problems, blood vessel disorders, major injury/surgery, kidney/liver disease, alcohol use, mental/mood disorders, falls/injuries.
- When taking Coumadin (warfarin), avoid getting injections into the muscles. If you must have an injection into a muscle, such as for a flu shot, it should be administered to the arm. This will make it easier to monitor for bleeding and/or apply pressure bandages if needed.
- Coumadin (Warfarin) may cause stomach bleeding, and daily alcohol use can increase the risk and affect how it works. Limit alcoholic beverages and ask your doctor or pharmacist about how much you may safely drink.
- If you have been having difficulty eating, have been ill or have had an infection that causes fever, vomiting, or diarrhea for more than 2 days, or have started taking any antibiotic medications, contact your doctor or pharmacist as soon as possible, as these conditions can affect the way warfarin works.
- To lower the chance of getting cut, bruised, or injured, use great caution with sharp objects like safety razors and nail cutters. Use electric razor when shaving, soft toothbrush when brushing teeth, avoid contact sports, and if injured, especially if head is hit, call doctor right away.
Frequently Asked Questions (FAQ)
How is Coumadin (warfarin) taken?
Coumadin (warfarin) is typically taken orally in the form of tablets or capsules. The recommended dose is 2 to 5 milligrams (mg) as a single dose once per day. Your doctor may adjust the dose if needed, but it is usually not more than 10 mg per day.
Does Coumadin (warfarin) interact with other medications?
Coumadin (warfarin) can interact with other medications, including other anticoagulants and certain antibiotics and anti-anxiety drugs. Tell your doctor about all the medications you are taking, including over-the-counter drugs, before starting to take Coumadin (warfarin).
What should I do if I miss a dose of warfarin?
If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and take the next dose as scheduled. Do not take a double dose!
Who should not take Coumadin?
Coumadin should not be taken by pregnant women, people with a history of bleeding disorders, people with uncontrolled high blood pressure, and people who have had recent major surgery.
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