Mood and Behavior Changes
Chantix can cause changes in mood, thinking, or behavior in some people.
These may include:
- Agitation
- Irritability
- Depression
- Unusual behavior
- Suicidal thoughts or actions
Tell your healthcare provider right away if you notice new or worsening mood or behavior changes.
Seek urgent medical help if you have thoughts of harming yourself.
Kidney Problems
Varenicline is removed from the body mainly through the kidneys.
If you have moderate or severe kidney impairment, your dose may need to be reduced.
Tell your healthcare provider if you have kidney disease before starting Chantix.
Heart Problems
Some people with cardiovascular disease may need closer monitoring while taking Chantix.
Tell your healthcare provider if you have a history of heart attack, stroke, chest pain, or other heart problems.
Seek medical attention if you develop new or worsening chest pain, severe shortness of breath, or other concerning heart symptoms.
Allergic Reactions
Serious allergic reactions can occur.
Seek medical attention right away if you develop:
- Hives
- Swelling of the face, lips, tongue, or throat
- Trouble breathing
- Severe rash
Nausea and Stomach Problems
Nausea is one of the most common side effects of Chantix.
Taking Chantix after food with a full glass of water may help.
Tell your healthcare provider if nausea, vomiting, or other stomach problems are severe or do not improve.
Seizures
Seizures have been reported in some people taking Chantix.
The risk may be higher if you have a history of seizures or other factors that make seizures more likely.
Tell your healthcare provider if you have ever had a seizure.
Vision Changes
Chantix may sometimes cause blurred vision or other changes in eyesight.
Use caution with driving or other activities that require clear vision until you know how the medication affects you.
Driving and Operating Machinery
Chantix may cause dizziness, sleepiness, trouble concentrating, or other effects that can affect alertness.
Avoid driving or operating machinery until you know how the medication affects you.
Pregnancy
Tell your healthcare provider if you are pregnant or planning to become pregnant.
Chantix should be used during pregnancy only when the expected benefit outweighs the possible risk.
Breastfeeding
Tell your healthcare provider if you are breastfeeding.
It is not known whether varenicline passes into human breast milk in meaningful amounts.
Your healthcare provider can help decide whether Chantix is appropriate for you.
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