Cafergot (Caffeine/Ergotamine)

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Cafergot Brand
Dosage Quantity & Price
Caffeine/Ergotamine (Generic alternate to Cafergot) Generic

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Table of contents:

Cafergot is used to treat or prevent certain types of headaches, including vascular headaches such as migraine and cluster headaches. It is a combination medication that contains ergotamine tartrate and caffeine. Caffeine is a stimulant that causes the narrowing of blood vessels (vasoconstriction). Ergotamine is an ergot alkaloid (ER-got AL-ka-loid) that works by narrowing blood vessels around the brain. Caffeine and ergotamine are a combination medicine used to treat or prevent a migraine-type headache.

Cafergot can only treat a headache that has already begun. It works by constricting blood vessels in the brain, which helps to reduce the severity of the headache.

Uses and Dosage

Cafergot is a medication that is available in tablet form to be taken orally with or without food, as indicated by your doctor. At the first sign of headache, typically two tablets are taken, followed by one tablet every thirty minutes until the headache is relieved. Cafergot should not be used for more than 10 days per month. Do not take more than a total of six tablets per headache attack or ten tablets within a seven-day period.

If your physician has prescribed Cafergot to help prevent certain types of headaches, such as cluster headaches, adhere to the doctor's instructions exactly, usually for short-term treatment of two to three weeks. If you are at risk for heart problems, your physician may perform a heart examination before you start taking Cafergot tablets.

Side effect

Common Side Effects of Cafergot (Caffeine/Ergotamine):

  • Dizziness
  • Mild itching
  • Nausea
  • Spinning sensation
  • Swelling
  • Vomiting
  • Weakness

Serious Side Effects of Cafergot (Caffeine/Ergotamine):

  • Anxiety
  • Blue colored fingers or toes
  • Blurred vision
  • Buzzing in your ears
  • Chest discomfort
  • Chest pain
  • Confusion
  • Difficulty breathing
  • Dry cough or hack
  • Fast or slow heart rate
  • Hives
  • Leg weakness
  • Little or no urinating
  • Muscle pain in your arms or legs
  • Numbness and tingling
  • Pain in your hands or feet
  • Problems with vision or balance
  • Seizures
  • Severe headache
  • Severe pain in your stomach or lower back
  • Shortness of breath
  • Slurred speech
  • Sudden severe headache
  • Swelling of your face, lips, tongue, or throat
  • Uneven heartbeats
  • Weak pulses in your arms and legs

Form and Strength

Cafergot (Caffeine/Ergotamine) is available in the following forms and strength:

Cafergot: Tablet

  • 100/1 mg


  • Cafergot can cause side effects, such as nausea, vomiting, dizziness, and increased blood pressure.
  • Cafergot may cause a decrease in blood flow to the hands and feet, which can lead to symptoms such as cold hands and feet, numbness, tingling, or pain.
  • Cafergot may impair your ability to operate machinery, drive a car, or perform other potentially dangerous activities.
  • Cafergot may increase the risk of heart attack, especially in people with heart disease or risk factors for heart disease.
  • Cafergot may increase the risk of serotonin syndrome when used with other drugs that increase serotonin levels in the brain.
  • Cafergot may interact with other drugs, tell your doctor about all the drugs you are taking.
  • Cafergot may not be safe or effective for children.
  • Cafergot may worsen certain medical conditions, such as liver and kidney disease, high blood pressure, and heart disease.
  • Cafergot should not be used during pregnancy unless the potential benefits justify the potential risks to the fetus. Cafergot has been shown to be harmful to the fetus in animal studies.
  • Cafergot should not be used in patients with uncontrolled hypertension, peripheral vascular disease, sepsis, hepatic, renal, or cardiac disease.
  • Pregnant women should also be cautious about taking Cafergot as it may harm the fetus.
  • Serious and/or life-threatening peripheral ischemia has been associated with the administration of Cafergot with potent CYP 3A4 inhibitors (a type of medication that affects the metabolism of other medications in the body).

Frequently Asked Questions (FAQ)

Can Cafergot be used in children?

Cafergot may not be safe or effective for children. The safety and effectiveness of Cafergot in children have not been established.

How quickly does Cafergot work?

Cafergot typically starts to work within about 30 minutes to an hour after it is taken, although the exact time may vary depending on individual factors.

How long does the effect of Cafergot last?

The effects of Cafergot may last for several hours, although the length of time can vary depending on individual factors and the severity of the migraine attack.

Can Cafergot be taken with food?

Yes, Cafergot can be taken with or without food. However, taking it with food may help to reduce the risk of nausea and vomiting.

What should I do if I miss a dose of Cafergot?

If you miss a dose of Cafergot, you can take it as soon as you remember. However, if it is almost time for your next dose, you should skip the missed dose and continue with your regular dosing schedule.

Can Cafergot be addictive?

Cafergot is not considered to be addictive. However, it may cause dependence if used for prolonged periods of time.


It's important to purchase Cafergot from verified Canadian pharmacy.

Additional information

Generic name:






Quantities Available:

30, 60, 90


Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Cafergot (Caffeine/Ergotamine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Cafergot (Caffeine/Ergotamine).