Cafergot contains two active ingredients, ergotamine and caffeine. It is a prescription medication used to treat certain types of migraine headaches and related vascular headaches.
Cafergot is generally used to stop a migraine attack after it begins. It is not considered a first-choice option for routine migraine prevention.
Indications
Migraine Headaches
Cafergot may be used to treat migraine attacks.
A migraine is more than a typical headache. It is a neurological condition that can cause moderate to severe head pain along with other symptoms.
Migraine symptoms may include:
- Throbbing or pulsating head pain
- Pain that affects one or both sides of the head
- Nausea
- Vomiting
- Sensitivity to light
- Sensitivity to sound
- Sensitivity to smells
- Dizziness
- Visual changes or aura in some people
Cafergot works best when taken early in a migraine attack, according to the instructions provided by your healthcare provider.
Migraine With or Without Aura
Some people experience migraine with aura, while others do not.
An aura can occur before or during a migraine and may cause temporary neurological symptoms such as flashing lights, blind spots, tingling, or changes in vision.
Cafergot may be prescribed for certain migraine attacks whether or not an aura is present, depending on your medical history and treatment plan.
Certain Migraine Variants
Cafergot may also be used for certain migraine variants or vascular headaches when a healthcare provider determines that ergotamine treatment is appropriate.
Because different types of severe headaches can have different causes, a healthcare provider should evaluate your symptoms before Cafergot is used.
How Cafergot Works
Cafergot combines ergotamine and caffeine. These ingredients work together to reduce the processes involved in a migraine attack.
How Ergotamine Works
Ergotamine belongs to a class of medicines called ergot alkaloids.
During a migraine attack, changes in nerve signaling and blood vessel activity occur around the brain. Ergotamine acts on several receptors, including serotonin receptors, and causes certain blood vessels to narrow.
This vasoconstricting effect can help reduce migraine-related pain and other symptoms.
How Caffeine Works
Caffeine is included in Cafergot because it can improve the absorption of ergotamine.
This helps more ergotamine enter the bloodstream and may improve its migraine-relieving effect.
Caffeine can also affect blood vessel tone and may contribute to headache relief.
Combined Effect
The combination of ergotamine and caffeine helps reduce migraine symptoms by influencing both blood vessel activity and neurological signalling involved in an attack.
Taking the medication early in the migraine may improve its effectiveness.
What to Expect During Treatment
Cafergot is usually taken when migraine symptoms begin rather than on a regular daily schedule.
The medication may help reduce:
- Headache intensity
- Throbbing pain
- Nausea associated with migraine
- Sensitivity to light or sound
How quickly symptoms improve can vary from person to person.
If your migraine does not improve after using Cafergot as directed, do not continue taking extra doses beyond the prescribed limit. Contact your healthcare provider for advice.
Not for Everyday Migraine Prevention
Cafergot is generally used to treat an active migraine attack rather than to prevent migraines from occurring every day.
Frequent or excessive use can increase the risk of medication-overuse headaches and serious ergotamine-related side effects.
If you need migraine medication often, talk to your healthcare provider. A preventive migraine treatment may be more appropriate.
Why Careful Dosing Is Important
Ergotamine can strongly narrow blood vessels throughout the body, not only those involved in migraine.
Taking too much Cafergot can reduce blood flow to the arms, legs, heart, or other organs.
For this reason, never exceed the dose or weekly maximum prescribed by your healthcare provider.
Seek medical attention if you develop symptoms such as severe chest pain, unusual weakness, numbness or tingling in the hands or feet, cold or pale fingers or toes, or severe muscle pain.
Important Treatment Considerations
Tell your healthcare provider about all medications you take before using Cafergot.
Certain medicines can raise ergotamine levels in the body and increase the risk of dangerous blood vessel narrowing.
Cafergot may not be suitable for people with certain cardiovascular, circulation, liver, kidney, or blood pressure problems.
Use Cafergot only for the migraine or headache condition for which it was prescribed, and follow your healthcare provider’s dosing instructions carefully.
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