Indications
Aricept ODT is a medication used to treat dementia associated with Alzheimer's disease. It comes in an orally disintegrating tablet form (ODT) and contains the active ingredient donepezil hydrochloride. Aricept ODT works by increasing the levels of a certain chemical in the brain that is involved in memory and other cognitive processes.
Aricept ODT is available in dosages of 10 mg and is taken by allowing it to dissolve on the tongue and then following it with water. Aricept ODT may improve memory, awareness, and the ability to perform daily functions in patients with Alzheimer's disease, but it does not cure the disease.
Use and Dosage
Aricept ODT is available in the form of orally disintegrating tablet for oral administration. The tablet should only be removed from its protective pouch when it is time to take it and hands should be dried before handling the medication. The tablet should not be pushed through the foil due to the risk of damage. To take the dose, the tablet should be placed on the tongue, where it will quickly dissolve. Once it is dissolved completely, it should be followed with a glass of water.
Dosage for Aricept ODT is based on the individual's medical condition and response to treatment. It is usually taken once per day before bedtime, and insomnia should be discussed with the prescribing physician to consider switching to a morning dose. To minimize the risk of side effects like diarrhea and nausea, a low dose is recommended at the beginning of treatment, with gradual increases over weeks to months. The dosage should never be increased, nor the drug be used more often than prescribed.
If the patient does not take Aricept ODT for more than 7 consecutive days, speak with a prescribing physician before resuming the medication, as a lower dose may be necessary. To get the most benefit from the tablet, it should be taken regularly at the same time each day. The medication should only be stopped on the direct instruction of the prescribing physician, and it may take several weeks to achieve maximum therapeutic effect.
Side Effects
Common Side Effects of Aricept ODT (Donepezil):
- Feeling tired
- Loss of appetite
- Muscle pain
- Nausea
- Vomiting
- Diarrhea
- Sleep problems (insomnia)
Serious Side Effects of Aricept ODT (Donepezil):
- Bloody or tarry stools
- Coughing up blood
- Heartburn
- Light-headed feeling, like you might pass out
- New or worsening breathing problems
- New or worsening stomach pain
- Painful or difficult urination
- Seizure
- Slow heartbeats
Forms and Strength
Aricept ODT (Donepezil) is available in the following forms and strength:
Aricept ODT: Orally Disintegrating Tablet
- 10 mg
Cautions
- Allergic reactions: Do not take Aricept ODT if you are allergic to donepezil or any of the ingredients in the medication.
- Cardiovascular problems: Use with caution in patients with a history of heart or vascular problems, as the medication may slow down heart rate.
- Liver problems: Aricept ODT is primarily metabolized by the liver and should be used with caution in patients with liver disease.
- Gastrointestinal problems: Aricept ODT may cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and loss of appetite.
- Seizures: Aricept ODT may lower the convulsive threshold and should be used with caution in patients with a history of seizures.
- Interactions: Aricept ODT may interact with other medications, such as other cholinesterase inhibitors or anticholinergic drugs, and caution should be taken when using them together.
- Respiratory problems: Aricept ODT may cause bronchoconstriction, particularly in patients with a history of asthma or obstructive pulmonary disease.
- Sensitive patients: Use with caution in patients with a history of sensitivity to cholinomimetic agents.
- Renal problems: Use with caution in patients with renal disease.
- Pregnancy and breastfeeding: The safety of Aricept ODT during pregnancy and breastfeeding is not established.
- Donepezil overdose: Seek emergency medical attention if an overdose of donepezil is suspected.
Frequently Asked Questions (FAQ)
How long does it take for Aricept ODT to work?
Aricept ODT may take up to 4 weeks to start working, and the full effects may not be seen until after 3 months of treatment.
Can I stop taking Aricept ODT if I feel better?
No, do not stop taking Aricept ODT unless instructed by a prescribing physician. Abruptly stopping the medication may cause a worsening of symptoms.
Can Aricept ODT be used to treat dementia in other conditions besides Alzheimer's disease?
Aricept ODT is only approved for the treatment of dementia associated with Alzheimer's disease.
Can Aricept ODT be used in children?
Aricept ODT is not approved for use in children.
Resources
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020690s035,021720s008,022568s005lbl.pdf
- https://www.drugs.com/mtm/aricept-odt.html
- https://www.webmd.com/drugs/2/drug-93147/aricept-odt-oral/details
- https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=98e451e1-e4d7-4439-a675-c5457ba20975
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/21720lbl.pdf
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