Indications
Ampyra, also known as dalfampridine, is a prescription drug used to help improve walking ability in adults with multiple sclerosis (MS). Dalfampridine is a potassium channel blocker. It works by blocking tiny pores, or potassium channels.
Dalfampridine is a medication specifically for improving walking ability in adults with MS. Its efficacy has been demonstrated in randomized controlled clinical trials and several studies have suggested that its use can lead to improved quality of life for those suffering from MS.
Uses and Dosage
Ampyra comes in tablet form to be taken by mouth with or without food twice a day, as directed by a doctor. Swallow the tablet whole and not crush, chew, or break it as this can cause the drug to be released all at once, increasing the risk of side effects. If you are unable to swallow the tablets whole, talk to your doctor.
The dosage of the medication will depend on your medical condition and response to treatment, and you should not take more medication or take it more frequently than prescribed to reduce the risk of side effects such as seizures. Take no more than 2 doses per day, 12 hours apart.
Side Effect
Common Side Effects of Ampyra (Dalfampridine):
- Back pain
- Constipation
- Difficulty falling asleep or staying asleep
- Difficulty with balance
- Dizziness
- Headache
- Heartburn
- Nausea
- Pain or irritation in the nose or throat
- Weakness
- Worsening of multiple sclerosis symptoms
Serious Side Effects of Ampyra (Dalfampridine):
- "Pins and needles", or tingling feelings
- Blurred vision
- Burning
- Crawling
- Difficulty controlling your bladder or bowels
- Feeling sad or depressed
- Fever or chills
- Forgetful
- Itching
- Muscle cramps
- Numbness
- Pain in the back, side, or stomach
- Painful, difficult, or frequent urination
- Prickling
- Problems with swallowing
- Seizures
- Slurred speech
- Unusual tiredness or weakness
Form and Strength
Ampyra (Dalfampridine) is available in the following forms and strength:
Ampyra: Extended-Release Tablet
- 10 mg
Dalfampridine: Extended-Release Tablet
- 10 mg
Caution
- Ampyra increases the risk of seizures, so patients with a history of seizures or with certain medical conditions that increase the risk of seizures should use caution and discuss the risks and benefits of taking Ampyra with their doctor.
- Patients should not take more medication or take it more frequently than prescribed, as this can increase the risk of side effects.
- Patients who have a history of kidney problems should use caution when taking Ampyra because it is primarily excreted through the kidneys.
- Dalfampridine (the active ingredient in Ampyra) should be used with caution in nursing mothers because it is not known if it is excreted in human milk.
- Patients should talk to their doctor if they have any concerns about taking Ampyra with other medications or supplements, as some drug interactions may occur.
Frequently Asked Questions (FAQ)
Can Ampyra be used to treat other conditions besides multiple sclerosis?
No, Ampyra is only approved for use in improving walking ability in patients with multiple sclerosis.
How long does it take for Ampyra to start working?
The medication can start working within a few weeks of starting treatment, but it may take up to 2-4 weeks for patients to notice an improvement in walking ability.
Can Ampyra be taken during pregnancy or while breastfeeding?
The safety of Ampyra during pregnancy and breastfeeding is not known and talk to a healthcare professional before taking this medication in those situations.
What should I do if I miss a dose of Ampyra?
If you miss a dose of Ampyra, take the missed dose as soon as you remember. However, if it is almost time for your next dose, you should skip the missed dose and take your next dose at the scheduled time.
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