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Esbriet (Pirfenidone) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Esbriet

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Prescription Prescription Required FormationFormulation: Tablet

Pirfenidone

(Generic Alternative)

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Esbriet (active ingredient: pirfenidone) is a prescription medication used to treat idiopathic pulmonary fibrosis (IPF) in adults.

Idiopathic pulmonary fibrosis is a chronic lung disease that causes scarring (fibrosis) of the lungs. As the scarring worsens over time, the lungs become stiffer and less able to transfer oxygen into the bloodstream. This can lead to symptoms such as shortness of breath, persistent dry cough, fatigue, and reduced ability to perform daily activities.

Esbriet belongs to a class of medications known as antifibrotic agents. It works by slowing the processes that contribute to lung scarring, helping to reduce the progression of the disease.

Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Esbriet is indicated for the treatment of idiopathic pulmonary fibrosis (IPF) in adults.

While Esbriet does not cure IPF, it can help slow the progression of lung scarring and preserve lung function for a longer period of time.

How Esbriet Helps

  • Slows the progression of lung fibrosis
  • Helps preserve lung function
  • May reduce the rate of decline in breathing capacity
  • Supports long-term management of IPF
  • May help maintain quality of life

How Esbriet Works

Esbriet contains pirfenidone, which helps reduce the activity of cells and substances involved in the formation of scar tissue within the lungs.

Pirfenidone works by:

  • Reducing fibroblast activity (cells that produce scar tissue)
  • Decreasing collagen production and deposition
  • Limiting the development of new lung scarring

By slowing these processes, Esbriet helps reduce the progression of fibrosis and may help preserve lung function over time.

Because idiopathic pulmonary fibrosis is a long-term condition, Esbriet is generally taken continuously as prescribed by your healthcare provider. Regular follow-up appointments and lung function testing are important to monitor your response to treatment and assess disease progression.

Esbriet is taken by mouth and is available as capsules and tablets. It should be taken with food, usually three times daily, exactly as prescribed by your healthcare provider.

Taking Esbriet with food can help reduce side effects such as nausea, dizziness, and stomach upset. For best results, take each dose at approximately the same times every day and continue taking the medication regularly, even if you feel well.

Before starting Esbriet, tell your healthcare provider and pharmacist about all prescription medications, over-the-counter products, vitamins, and herbal supplements you take. Some products may interact with pirfenidone and affect how it works.

Starting Treatment

When beginning treatment with Esbriet, the dose is gradually increased over the first two weeks to help reduce the risk of side effects.

Week 1

  • Take 267 mg (1 capsule) by mouth three times daily with food

Week 2

  • Take 534 mg (2 capsules) by mouth three times daily with food

Week 3 and Beyond (Maintenance Dose)

  • Take 801 mg (3 capsules) by mouth three times daily with food

Once you reach the maintenance dose, your healthcare provider may prescribe the 801 mg tablet, which can simplify dosing by reducing the number of pills you need to take with each dose.

Important Tips

  • Take Esbriet with food every time you take a dose.
  • Follow the dose-escalation schedule exactly as directed.
  • Do not change your dose unless instructed by your healthcare provider.
  • If you miss a dose, follow your healthcare provider’s instructions and do not take extra doses to make up for a missed one.
  • Attend regular follow-up appointments to monitor your response to treatment.

Because idiopathic pulmonary fibrosis is a chronic condition, Esbriet is usually taken as a long-term treatment to help slow the progression of lung scarring and preserve lung function.

Common Side Effects of Esbriet (Pirfenidone):

  • Common cold symptoms
  • Diarrhea
  • Dizziness
  • Headache
  • Indigestion
  • Nausea
  • Poor appetite
  • Rash
  • Stomach pain or discomfort
  • Tiredness
  • Vomiting

Serious Side Effects of Esbriet (Pirfenidone):

  • Change in taste
  • Difficulty sleeping
  • General weakness
  • Heartburn
  • Itchiness
  • Joint pain
  • Non-heart-related chest pain
  • Sinus inflammation
  • Skin reaction from light
  • Weight loss

Esbriet (Pirfenidone) is available in the following forms and strength:

Pirfenidone: Tablet

  • 200 mg
  • 267 mg
  • 801 mg

Before starting Esbriet (pirfenidone), tell your healthcare provider about your complete medical history, including any liver problems, medications you take, and whether you are pregnant or breastfeeding.

Liver Monitoring

Esbriet can affect liver function, so your healthcare provider will perform blood tests before you begin treatment to check that your liver is working properly.

After starting treatment:

  • Liver function tests are typically performed monthly during the first 6 months of treatment.
  • After the first 6 months, testing is usually performed every 3 months, or as recommended by your healthcare provider.

Contact your healthcare provider immediately if you develop symptoms of liver problems, such as:

  • Yellowing of the skin or eyes (jaundice)
  • Dark urine
  • Persistent nausea or vomiting
  • Pain in the upper abdomen
  • Unusual tiredness or weakness

Pregnancy and Breastfeeding

If you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed, discuss this with your healthcare provider before taking Esbriet.

The safety of Esbriet during pregnancy and breastfeeding has not been fully established. Your healthcare provider can help determine whether the potential benefits of treatment outweigh any potential risks.

Drug Interactions

Before taking Esbriet, tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, and herbal supplements you use.

Some medications may interact with pirfenidone and affect how well it works or increase the risk of side effects.

Serious Skin Reactions

Although uncommon, Esbriet may cause serious skin reactions.

Contact your healthcare provider immediately if you develop:

  • Severe rash
  • Skin blisters
  • Hives
  • Sores in the mouth
  • Peeling skin
  • Any other severe skin symptoms

Sensitivity to Sunlight

Esbriet can make your skin more sensitive to sunlight, increasing the risk of sunburn.

To help protect your skin:

  • Avoid prolonged exposure to direct sunlight.
  • Wear protective clothing, a hat, and sunglasses when outdoors.
  • Apply a broad-spectrum sunscreen regularly.
  • Avoid tanning beds and sunlamps.

Contact your healthcare provider if you develop a severe sunburn or significant skin reaction.

Stomach and Digestive Problems

Some people experience digestive side effects while taking Esbriet, especially during the first few months of treatment.

Common symptoms may include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Indigestion
  • Stomach discomfort

Taking Esbriet with food can help reduce these side effects. In many cases, digestive symptoms improve over time as your body adjusts to the medication.

Regular follow-up appointments and laboratory monitoring can help ensure that Esbriet remains safe and effective throughout your treatment.

How Long Does It Take for Esbriet to Work?

Esbriet works gradually and may take several weeks or even months before its effects become noticeable. Because idiopathic pulmonary fibrosis (IPF) progresses slowly, the benefits of treatment are often seen over time rather than immediately. It is important to continue taking Esbriet exactly as prescribed, even if you do not notice any immediate improvement in your symptoms.

Does Esbriet Help People Live Longer?

Studies have shown that people with idiopathic pulmonary fibrosis who take Esbriet may have better long-term outcomes compared with those who do not receive antifibrotic treatment. By slowing the progression of lung scarring, Esbriet may help preserve lung function and support long-term disease management. Your healthcare provider can discuss the expected benefits of treatment based on your individual condition.

How Quickly Does Pirfenidone (Esbriet) Work?

Pirfenidone does not work quickly and must be taken consistently over a long period of time to achieve its full benefits. Unlike some medications, Esbriet does not usually provide immediate symptom relief or make breathing noticeably easier. Instead, its primary purpose is to slow the progression of lung fibrosis and help preserve lung function over time.

Can Esbriet Be Taken with Other Medications?

Esbriet may interact with certain medications, vitamins, and herbal supplements. Before starting treatment, tell your healthcare provider about everything you take, including prescription medications, over-the-counter products, vitamins, and herbal supplements. Your healthcare provider can review your medications, identify potential interactions, and determine whether any adjustments are needed to help ensure Esbriet is safe and effective for you.

REVIEWS

Additional Information Book
Generic name:

Pirfenidone

Formulation:

Tablet

Strength(s):

200mg, 267mg, 801mg

Quantities Available:

30, 84, 90, 100, 180, 300

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Esbriet can I order at once from a Canadian pharmacy?

When ordering Esbriet (pirfenidone) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure continuous treatment without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Esbriet is typically prescribed in a dosage of 801 mg, taken three times daily with food. So for a 90-day supply, you would generally order 270 tablets (90 days x 3 tablets per day).

Do you sell pirfenidone?

Yes, we do sell pirfenidone on our website. You can enjoy low prices for this medication. However, please note that you will need a valid prescription from your healthcare provider in order to purchase pirfenidone from us. We require this prescription to dispense the medication safely and legally. You can conveniently provide your prescription by mailing, faxing, or uploading it through your online account on our website.

Do you offer shipping of Esbriet (pirfenidone) to the United States?

Yes, we ship Esbriet (pirfenidone) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Esbriet (Pirfenidone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Esbriet (Pirfenidone).