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Amitiza (lubiprostone) is a prescription medication used to treat certain types of constipation in adults. It works by increasing the amount of fluid in the intestines, which helps soften stool, promote regular bowel movements, and make stools easier to pass.
Amitiza is used to treat chronic idiopathic constipation (CIC) in adults. Chronic idiopathic constipation is a condition characterized by ongoing constipation that does not have a known underlying cause. People with CIC may experience:
By helping the intestines retain more fluid, Amitiza can improve stool consistency and increase the frequency of bowel movements.
Amitiza is also approved for the treatment of irritable bowel syndrome with constipation (IBS-C) in adult women. IBS-C is a digestive disorder that combines chronic constipation with symptoms such as:
For people with IBS-C, Amitiza may help relieve constipation and improve overall bowel function, which can contribute to greater comfort and quality of life.
Amitiza belongs to a group of medications called chloride channel activators. It works by activating specific chloride channels in the lining of the intestines.
When these channels are activated, more chloride-rich fluid is released into the intestines. This additional fluid helps soften stool, increases the movement of contents through the digestive tract, and makes bowel movements easier and more regular.
By improving the flow of fluid into the intestines, Amitiza can help reduce constipation symptoms and support healthier bowel function. While Amitiza does not cure the underlying condition, it can be an effective long-term treatment option for managing chronic constipation and improving digestive comfort when taken as prescribed by a healthcare provider.
Amitiza is available as an oral capsule and should be taken exactly as prescribed by your healthcare provider. To help reduce the risk of side effects such as nausea, Amitiza should be taken with food and water, usually twice daily.
Swallow the capsule whole with a full glass of water. Do not crush, chew, open, or break the capsule, as this may affect how the medication works and could increase the risk of side effects. Taking Amitiza at the same times each day can help you remember your doses and maintain consistent symptom relief.
It is important to follow your healthcare provider’s instructions carefully and not take more than the prescribed dose. Taking extra medication will not improve your symptoms faster and may increase the likelihood of side effects.
The recommended dose of Amitiza depends on the condition being treated.
Chronic Idiopathic Constipation (CIC)
For adults with chronic idiopathic constipation, the usual dose is:
This dose helps increase fluid in the intestines, making stools softer and easier to pass.
Opioid-Induced Constipation (OIC)
For adults experiencing constipation related to opioid pain medications, the usual dose is:
Your healthcare provider may adjust treatment based on your response and overall health.
Irritable Bowel Syndrome with Constipation (IBS-C)
For adult women with irritable bowel syndrome with constipation, the usual dose is:
This lower dose is specifically approved for women with IBS-C and may help relieve constipation, bloating, and abdominal discomfort associated with the condition.
If you miss a dose of Amitiza, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
Do not take two doses at the same time or take extra medication to make up for a missed dose.
When taken consistently as prescribed, Amitiza can help improve bowel function, reduce constipation symptoms, and support greater digestive comfort over time.
Amitiza and its generic alternative of Lubiprostone are available in the following forms and strengths.
Before taking Amitiza, tell your healthcare provider about all of your medical conditions, allergies, and medications. Certain health conditions may affect whether Amitiza is safe for you to use.
You should not take Amitiza if you have a known or suspected blockage in your digestive tract. Taking Amitiza when a bowel obstruction is present may worsen the condition and could lead to serious complications.
Amitiza should also not be used if you have severe diarrhea. The medication may worsen diarrhea and increase the risk of dehydration. Contact your healthcare provider if you develop severe or persistent diarrhea while taking Amitiza.
One of the most common side effects of Amitiza is nausea. Taking the medication with food and water can help reduce the likelihood of this side effect and make it easier to tolerate treatment.
If nausea becomes severe or does not improve, speak with your healthcare provider.
Do not take Amitiza if you have had a previous allergic reaction to lubiprostone or any of the ingredients in the medication.
Seek immediate medical attention if you experience symptoms of an allergic reaction, including:
Always inform your healthcare provider about any medication allergies before starting treatment.
If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of Amitiza with your healthcare provider before starting treatment.
Your healthcare provider can help determine whether Amitiza is appropriate for you based on your individual circumstances and treatment needs.
Amitiza capsules should be swallowed whole with food and water. Do not crush, chew, break, or open the capsules.
Altering the capsule may affect how the medication is absorbed and could reduce its effectiveness or increase the risk of side effects.
Older adults may be more sensitive to certain side effects of Amitiza and should use the medication with caution. Your healthcare provider may monitor your response to treatment more closely, particularly if you have other medical conditions or take multiple medications.
Using Amitiza as directed and following your healthcare provider’s recommendations can help improve constipation symptoms while reducing the risk of potential side effects and complications.
Amitiza may begin working relatively quickly for many people. Some patients experience relief from constipation and have a bowel movement within 24 hours of starting treatment. In clinical studies, many people experienced a spontaneous bowel movement during the first day of treatment. However, response times can vary from person to person. Some individuals may notice improvement sooner, while others may require several days of consistent use before experiencing the full benefits of the medication.
Amitiza is more likely to cause nausea when taken without food. Nausea is one of the most common side effects of the medication and can sometimes be severe enough to interfere with daily activities. Taking Amitiza with food and water can help reduce the likelihood and severity of nausea and may improve overall tolerance of the medication. For this reason, it is important to follow your healthcare provider’s instructions and take each dose with a meal and a full glass of water.
The amount of Amitiza you should take depends on the condition being treated and your healthcare provider’s recommendations. For chronic idiopathic constipation (CIC) and opioid-induced constipation (OIC), the usual dose is 24 mcg twice daily, while for irritable bowel syndrome with constipation (IBS-C) in adult women, the usual dose is 8 mcg twice daily. The maximum recommended dose of Amitiza is 48 mcg per day. Do not take more than the prescribed amount, and always follow the dosing instructions provided by your healthcare provider. If you have questions about your dose, speak with your healthcare provider or pharmacist before making any changes to your treatment plan.
| Generic name: | Lubiprostone |
|---|---|
| Formulation: | Capsule, Soft Gelatin Capsule |
| Strength(s): | 8mcg, 24mcg |
| Quantities Available: | 60, 180 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Amitiza (lubiprostone) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Amitiza is commonly prescribed in dosages of 8 mcg or 24 mcg, taken twice daily, depending on the condition being treated. For a 90-day supply, this means you would order 180 capsules (90 days x 2 capsules per day).
Yes, we sell lubiprostone. You can enjoy low prices on this medication through our website. Please note that you will need a valid prescription from your healthcare provider to purchase lubiprostone. We require this to dispense the medication. You can mail, fax, or upload your prescription through your online account.
Yes, we ship Amitiza (lubiprostone) to both the United States and Puerto Rico.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Amitiza (Lubiprostone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Amitiza (Lubiprostone).
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