Before taking Janumet, tell your healthcare provider about your complete medical history, including any allergies, medical conditions, and all medications you are taking. This helps ensure the medication is safe and appropriate for you.
Medical Procedures and Contrast Dye
Tell your healthcare provider or dentist that you are taking Janumet before:
- Any surgery.
- An X-ray or CT scan that uses iodinated contrast dye.
Your healthcare provider may recommend temporarily stopping Janumet before and after the procedure to reduce the risk of kidney problems and a rare but serious side effect called lactic acidosis. Follow your healthcare provider’s instructions carefully about when to stop and restart the medication.
Allergic Reactions
Do not take Janumet if you are allergic to sitagliptin, metformin, or any of the ingredients in the medication.
Some inactive ingredients may also cause allergic reactions in certain people. If you are unsure about the ingredients, ask your pharmacist for more information.
Seek emergency medical attention immediately if you develop signs of a serious allergic reaction, including:
- Rash or hives.
- Severe itching.
- Swelling of the face, lips, tongue, or throat.
- Difficulty breathing or swallowing.
Pregnancy
If you are pregnant, planning to become pregnant, or breastfeeding, tell your healthcare provider before taking Janumet.
Pregnancy can affect blood sugar levels and may require changes to your diabetes treatment plan. Your healthcare provider will determine the safest way to manage your blood sugar during pregnancy.
Kidney Problems
Janumet should not be used by people with severe kidney disease or diabetic ketoacidosis.
Your healthcare provider will perform blood tests before starting treatment and periodically during treatment to monitor your kidney function and determine whether Janumet remains safe for you.
Tell your healthcare provider if you notice symptoms that may suggest kidney problems, such as:
- Swelling of the feet or ankles.
- Changes in urination.
- Unusual fatigue.
- Shortness of breath.
Dizziness and Blurred Vision
Janumet may cause blurred vision, dizziness, or drowsiness, particularly if your blood sugar becomes too high or too low.
Until you know how Janumet affects you, do not drive, operate machinery, or perform activities that require alertness or clear vision.
Monitor your blood sugar regularly and follow your healthcare provider’s recommendations to help keep your blood sugar within your target range.
Regular Monitoring
While taking Janumet, your healthcare provider may regularly monitor your:
- Blood sugar levels.
- Kidney function.
- Vitamin B12 levels (during long-term treatment).
- Overall response to therapy.
Keeping your follow-up appointments and having regular blood tests can help ensure the medication remains safe and effective.
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