Mexiletine is available in capsule form and comes in strengths of 100 mg, 150 mg, and 200 mg and it is taken by mouth. Typically, it is taken three times a day, every 8 hours, but once arrhythmias have been controlled with Mexiletine, it can be taken twice daily, every 12 hours. Mexiletine should be taken with food or an antacid to prevent stomach upset, and at around the same time every day. Your doctor may start you on an average dose and then gradually increase or decrease your dose, not more than once every 2 to 3 days.
Take Mexiletine exactly as directed and not take more or less of it or take it more often than prescribed. Mexiletine controls arrhythmias but does not cure them. Even if you feel well, continue taking Mexiletine as prescribed. Do not stop taking Mexiletine suddenly, as doing so can cause your condition to become worse.
The typical dosing for Mexiletine is a starting dose of 200 mg or 300 mg by mouth every 8 hours in adults. For some patients, the dose may need to be increased up to 400 mg every 8 hours. If the medication is effective, the dosing schedule may be changed to every 12 hours while maintaining the same total daily dose.
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