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Glucophage

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Prescription Prescription Required FormationFormulation: Tablet

Metformin

(Generic Alternative)

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Glucophage (active ingredient: metformin) is a prescription medication used to help control blood sugar levels in people with type 2 diabetes mellitus.

It is approved for use in adults and children 10 years of age and older with type 2 diabetes. Glucophage is used along with a healthy diet and regular exercise to improve blood sugar control.

Type 2 Diabetes Mellitus

Type 2 diabetes is a long-term condition in which the body does not use insulin properly (known as insulin resistance) or does not produce enough insulin to keep blood sugar levels within a healthy range.

High blood sugar can lead to symptoms such as:

  • Increased thirst.
  • Frequent urination.
  • Increased hunger.
  • Blurred vision.
  • Fatigue.
  • Slow-healing cuts or sores.

If left untreated, consistently high blood sugar can increase the risk of serious complications, including heart disease, kidney disease, nerve damage, and vision problems.

When combined with healthy lifestyle changes, Glucophage helps lower blood sugar levels and reduce the risk of diabetes-related complications.

How Does Glucophage Work?

Glucophage belongs to a group of medications called biguanides.

It lowers blood sugar in several ways without stimulating the pancreas to produce more insulin. Specifically, Glucophage works by:

  • Reducing the amount of glucose produced by the liver.
  • Improving your body’s sensitivity to insulin, allowing insulin to work more effectively.
  • Helping muscle cells absorb and use glucose more efficiently.
  • Reducing the amount of glucose absorbed from food in the intestines.

Together, these effects help lower blood sugar levels throughout the day.

Unlike some other diabetes medications, Glucophage does not usually cause low blood sugar (hypoglycemia) when taken by itself. However, low blood sugar can occur if it is used with insulin or certain other diabetes medications.

When taken consistently and combined with a healthy diet, regular physical activity, and weight management when appropriate, Glucophage can help:

  • Improve blood sugar control.
  • Lower HbA1c (average blood sugar over time).
  • Reduce the risk of diabetes-related complications.
  • Support long-term diabetes management.

Continue taking Glucophage exactly as prescribed, even if you feel well, as high blood sugar often does not cause noticeable symptoms.

Glucophage is available as an oral tablet that should be taken exactly as prescribed by your healthcare provider.

It is usually taken 1 to 3 times a day with meals. Taking Glucophage with food helps reduce stomach-related side effects such as nausea, diarrhea, and stomach upset.

Swallow the tablet with a full glass of water. Unless your healthcare provider instructs you otherwise, drink plenty of fluids while taking this medication to help maintain normal kidney function.

Your healthcare provider will determine the right dose based on your blood sugar levels, kidney function, and how well you tolerate the medication. To reduce the risk of side effects, treatment is usually started with a low dose, which is gradually increased as needed.

If you are scheduled for an imaging test or medical procedure that requires an iodinated contrast dye (such as certain CT scans or angiograms), tell your healthcare provider that you are taking Glucophage. You may need to temporarily stop the medication before or after the procedure while your kidney function is checked.

Recommended Dosages

Adults

The usual starting dose of Glucophage is:

  • 500 mg by mouth twice daily with meals, or
  • 850 mg by mouth once daily with a meal.

If additional blood sugar control is needed, depending on your blood sugar levels and how well you tolerate the medication your healthcare provider may increase your dose by:

  • 500 mg each week, or
  • 850 mg every 2 weeks.

The maximum recommended daily dose is 2,550 mg.

For people taking more than 2,000 mg per day, dividing the daily dose into three doses taken with meals may improve tolerability and help reduce stomach-related side effects.

Important Tips

  • Take Glucophage with food to help reduce stomach upset.
  • Try to take your doses at the same times each day.
  • Continue following your recommended diet and exercise plan, as these are important parts of managing type 2 diabetes.
  • Do not stop taking Glucophage without first consulting your healthcare provider, even if your blood sugar levels improve.
  • Your healthcare provider may recommend regular blood tests to monitor your blood sugar, HbA1c, kidney function, and vitamin B12 levels during treatment.

Common Side Effects of Glucophage (Metformin):

  • Diarrhea
  • Headache
  • Metallic taste in the mouth
  • Nausea
  • Stomach pain
  • Vomiting
  • Weakness

Serious Side Effects of Glucophage (Metformin):

  • A feeling of cold in your hands or feet
  • Chest pain
  • Difficulty breathing or shortness of breath
  • Dizziness
  • Extreme weakness or fatigue
  • Lightheadedness
  • Nausea or vomiting
  • Rash or hives
  • Sleepiness or drowsiness
  • Stomach pains
  • Unusual muscle pain

Glucophage (Metformin) is available in the following forms and strength:

Glucophage: Tablet

  • 500 mg
  • 850 mg
  • 1000 mg

Metformin: Tablet

  • 500 mg
  • 850 mg
  • 1000 mg

Before taking Glucophage, tell your healthcare provider about your complete medical history, including any allergies, medical conditions, and all medications you are taking. This helps ensure the medication is safe for you and reduces the risk of serious side effects.

Tell Your Healthcare Provider About Your Medical History

Before starting Glucophage, let your healthcare provider know if you have or have ever had:

  • Kidney disease.
  • Liver disease.
  • Severe breathing or lung problems.
  • Blood disorders.
  • Heart failure or other heart conditions.
  • A history of lactic acidosis.
  • Heavy alcohol use.

Also, tell your healthcare provider about all prescription medications, over-the-counter medicines, vitamins, herbal products, and dietary supplements you are taking, as some may interact with Glucophage.

Allergic Reactions

Do not take Glucophage if you are allergic to metformin or any of the ingredients in the medication.

Seek emergency medical attention immediately if you develop signs of a serious allergic reaction, including:

  • Rash or hives.
  • Severe itching.
  • Swelling of the face, lips, tongue, or throat.
  • Severe dizziness.
  • Difficulty breathing or swallowing.

Alcohol

Limit or avoid drinking alcohol while taking Glucophage.

Alcohol can increase the risk of lactic acidosis, a rare but serious side effect of metformin. It may also increase your risk of developing low blood sugar (hypoglycemia), especially if you are taking other diabetes medications.

Talk to your healthcare provider about whether it is safe for you to consume alcohol while taking Glucophage.

Pregnancy and Birth Control

Metformin may restore normal ovulation in some people, which can increase the chance of becoming pregnant, even if you have had irregular menstrual cycles.

If pregnancy is not planned, discuss effective birth control options with your healthcare provider.

If you are pregnant, planning to become pregnant, or breastfeeding, tell your healthcare provider before taking Glucophage. During pregnancy, your healthcare provider will determine whether Glucophage is appropriate for you. In some cases, insulin may be recommended instead to help manage blood sugar levels.

Medical Procedures Using Contrast Dye

Tell your healthcare provider if you are scheduled for an X-ray, CT scan, angiogram, or other imaging test that uses an iodinated contrast dye injected into a vein.

You may need to temporarily stop taking Glucophage before or after the procedure because contrast dye can affect kidney function and increase the risk of lactic acidosis in certain people. Your healthcare provider will advise you when it is safe to restart the medication after your kidney function has been checked.

Lactic Acidosis

Although rare, Glucophage can cause lactic acidosis, a serious medical emergency that requires immediate treatment. The risk is higher in people with kidney disease, severe liver disease, dehydration, heavy alcohol use, or certain heart conditions.

Seek emergency medical attention immediately if you develop symptoms such as:

  • Extreme weakness or unusual tiredness.
  • Muscle pain.
  • Trouble breathing.
  • Severe stomach pain.
  • Nausea or vomiting that does not go away.
  • Feeling cold, especially in your arms and legs.
  • Dizziness or lightheadedness.
  • Slow or irregular heartbeat.

Regular monitoring of your kidney function is recommended while taking Glucophage to help reduce the risk of this rare but serious complication.

How should I take Glucophage?

Take Glucophage exactly as prescribed by your healthcare provider. It is usually taken with meals, 1 to 3 times a day, depending on your prescribed dose. Taking Glucophage with food helps reduce stomach-related side effects such as nausea and diarrhea. If you are taking an extended-release (ER) tablet, swallow it whole. Do not crush, chew, or split the tablet, as this can affect how the medication is released into your body.

Can Glucophage be taken with other medications?

Yes. Glucophage is commonly used together with other diabetes medications when additional blood sugar control is needed. These may include insulin, pioglitazone, sulfonylureas, and other diabetes treatments. Always tell your healthcare provider about all prescription medications, over-the-counter medicines, vitamins, and herbal supplements you are taking so they can check for potential drug interactions and ensure your treatment plan is appropriate.

What is the recommended starting dose of Glucophage?

For most adults with type 2 diabetes, the usual starting dose is 500 mg by mouth twice daily with meals or 850 mg by mouth once daily with a meal. Your healthcare provider may gradually increase your dose based on your blood sugar levels and how well you tolerate the medication. Starting with a lower dose helps reduce the risk of stomach-related side effects.

Can I crush or chew Glucophage tablets?

If you are taking immediate-release Glucophage tablets, swallow them whole with a glass of water. If you are prescribed extended-release Glucophage tablets, do not crush, chew, or split them, as this can cause the medication to be released too quickly and may increase the risk of side effects.

REVIEWS

Additional Information Book
Generic name:

Metformin, Metformin Hydrochloride

Formulation:

Tablet

Strength(s):

500mg, 850mg, 1000mg

Quantities Available:

84, 90, 100, 168

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Glucophage can I order at once from a Canadian pharmacy?

When ordering Glucophage (metformin) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Glucophage is commonly prescribed in dosages of 500 mg, 850 mg, or 1000 mg taken multiple times per day. For example, if you are prescribed 850 mg taken three times daily, for a 90-day supply, you would order 270 tablets (90 days x 3 tablets per day).

Do you sell metformin?

Yes, we sell metformin! You can enjoy low prices on your medication by ordering from our website. To place an order, you will need a valid prescription from your healthcare provider, which we require to dispense the medication safely and accurately. You can submit your prescription by mail, fax, or by uploading it through your online account.

Do you offer shipping of Glucophage (metformin) to the United States?

Yes, we ship Glucophage (metformin) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Glucophage (Metformin). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Glucophage (Metformin).