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Dostinex contains cabergoline, a prescription medicine used to treat high levels of prolactin in the blood, a condition known as hyperprolactinemia. In adults, it may be used when the cause is unknown or when the high prolactin level is related to a pituitary tumor.
Prolactin is a hormone made by the pituitary gland, a small gland located at the base of the brain. It plays an important role in breast development and milk production.
When prolactin levels become too high, they can affect reproductive hormones and cause different symptoms. These may include irregular or missed menstrual periods, unwanted breast milk production, fertility problems, reduced sex drive, or erectile dysfunction.
Dostinex is mainly prescribed to lower prolactin levels in adults with hyperprolactinemia.
High prolactin levels can occur for different reasons. In some people, no clear cause is found. This is sometimes called idiopathic hyperprolactinemia.
In other people, the condition may be caused by a pituitary adenoma, which is usually a noncancerous tumor of the pituitary gland that produces excess prolactin.
By lowering prolactin levels, Dostinex may help improve problems caused by excess prolactin.
Depending on the person, treatment may help:
The response to treatment depends on the cause and severity of the condition.
Dostinex belongs to a group of medicines called dopamine agonists.
Dopamine is a natural chemical messenger in the body. One of its functions is to tell the pituitary gland to reduce the release of prolactin.
Cabergoline acts mainly on dopamine D2 receptors in the pituitary gland. By copying the effects of dopamine, it reduces prolactin production and lowers the amount of prolactin circulating in the blood.
Dostinex can be prescribed when hyperprolactinemia is caused by a prolactin-producing pituitary adenoma, often called a prolactinoma.
The main purpose of the medication is to lower prolactin levels. Your healthcare provider may also monitor the pituitary gland and tumor size when appropriate.
Cabergoline has dopamine-related effects and has been used for Parkinson’s disease in some countries and clinical settings. However, Parkinson’s disease is not an FDA-approved indication for Dostinex in the current U.S. prescribing information. The current U.S. indication is hyperprolactinemic disorders in adults.
This distinction is important because doses and safety considerations can differ depending on why cabergoline is being used.
Your healthcare provider will usually monitor your blood prolactin level to see how well Dostinex is working. The dose may be adjusted gradually until prolactin reaches an appropriate level.
Current prescribing information also recommends checking for heart valve disease before starting cabergoline, including an echocardiogram.
Unlike many medicines that are taken every day, Dostinex is commonly taken twice a week for hyperprolactinemia because cabergoline has a long-lasting effect.
The recommended starting dose is generally 0.25 mg twice weekly. Your healthcare provider may gradually increase the dose depending on your prolactin levels and response to treatment.
Dostinex is mainly used to treat high prolactin levels in adults, including cases caused by prolactin-producing pituitary tumors. It works by acting like dopamine and reducing the amount of prolactin released by the pituitary gland.
Take Dostinex only as prescribed and attend any recommended blood tests or heart checks so your healthcare provider can monitor how well the treatment is working and whether it remains safe for you.
Dostinex contains cabergoline and is taken by mouth as a tablet. For high prolactin levels, it is usually taken twice a week, rather than every day. It can be taken with or without food.
Take Dostinex exactly as prescribed by your healthcare provider. Because it is not usually taken every day, choosing the same two days each week or marking them on a calendar may help you remember your doses.
For adults with high prolactin levels, the usual starting dose is 0.25 mg twice a week. This equals a total starting dose of 0.5 mg per week.
Your healthcare provider may adjust the dose depending on your prolactin blood test results and how well you tolerate the medication.
If your prolactin level remains high, your healthcare provider may gradually increase the dose.
The dose may be increased by 0.25 mg twice weekly, but increases should generally be made no more often than every 4 weeks. This gradual adjustment gives your healthcare provider time to see how your body responds.
The maximum recommended dose in the current U.S. prescribing information is 1 mg twice weekly, or 2 mg per week.
Starting with a smaller dose and increasing it gradually may make the medication easier to tolerate.
Dostinex can cause side effects such as nausea, dizziness, headache, or a drop in blood pressure, so your healthcare provider will usually avoid increasing the dose too quickly.
Dostinex may be taken with or without food.
If the medicine causes nausea or stomach discomfort, taking it with food may make it easier to tolerate. Follow any specific instructions provided by your healthcare provider or pharmacist.
Because Dostinex is commonly taken twice weekly, it can be easy to forget a dose.
Your healthcare provider may recommend choosing two regular days that are spaced apart, such as Monday and Thursday. A calendar, medication organizer, or phone reminder can help you stay on schedule.
Your healthcare provider will usually check your blood prolactin level during treatment. These results help show whether Dostinex is working and whether your dose needs to be increased, decreased, or continued.
You should not change the amount you take based only on how you feel. High prolactin levels can improve before all symptoms disappear, so blood tests are an important part of treatment.
The length of treatment varies depending on why your prolactin level is high and how you respond to Dostinex.
Some people may need treatment for a longer period, particularly when high prolactin is related to a pituitary adenoma. Your healthcare provider will monitor your prolactin levels and determine how long treatment should continue.
If you miss a scheduled dose, follow the instructions given by your healthcare provider or pharmacist.
Do not take extra Dostinex or double your next dose unless your healthcare provider specifically tells you to do so. Because Dostinex has a long-lasting effect, missed-dose instructions may depend on when you remember the dose.
Cabergoline is used in some countries to prevent or suppress breast milk production after childbirth, but recommendations differ by country.
For example, some non-U.S. product information includes cabergoline dosing for lactation suppression.
However, the current U.S. prescribing information specifically advises against using Dostinex to inhibit or suppress normal postpartum lactation because of the potential for serious adverse reactions.
For this reason, postpartum dosing should not be presented as a standard Dostinex dosage without considering the country, reason for treatment, and advice of a healthcare provider.
Do not take Dostinex more often or in larger amounts than prescribed.
Taking more medication does not necessarily lower prolactin faster and may increase the risk of side effects. Your healthcare provider will increase the dose gradually if your prolactin level remains above the desired range.
For adults with hyperprolactinemia, Dostinex is generally started at 0.25 mg twice weekly. If needed, the dose may be increased gradually at intervals of at least 4 weeks, up to a maximum recommended dose of 1 mg twice weekly in current U.S. prescribing information.
Take your doses on the scheduled days, attend recommended blood tests, and speak with your healthcare provider before changing your dose or stopping treatment.
Dostinex (Cabergoline) is available in the following forms and strength:
Dostinex may cause dizziness, lightheadedness, or fainting, especially when you stand up quickly from a sitting or lying position. Stand up slowly and hold onto something if you feel unsteady.
Until you know how Dostinex affects you, use caution when driving, operating machinery, or doing other activities that require alertness.
Alcohol may make side effects such as dizziness or drowsiness worse. Talk to your healthcare provider about whether it is safe for you to drink alcohol while taking Dostinex.
Tell your healthcare provider if you have uncontrolled high blood pressure or have ever had an allergic reaction to cabergoline or other ergot-derived medicines.
Dostinex may not be appropriate for people with certain medical conditions or allergies.
Dostinex has been linked to heart valve problems, especially with higher doses or longer-term use.
Tell your healthcare provider if you have a history of heart valve disease or fibrotic conditions affecting the heart, lungs, or abdomen. Your healthcare provider may recommend heart tests, such as an echocardiogram, before or during treatment.
Dostinex can interact with certain medicines. Some drugs may reduce how well Dostinex works, while others may increase the risk of side effects.
Before starting treatment, tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and supplements you take.
If you are pregnant, planning to become pregnant, or think you may be pregnant, tell your healthcare provider before taking Dostinex.
Your healthcare provider will determine whether treatment should be continued based on your condition and the possible benefits and risks.
Dostinex can sometimes cause unusual changes in mood, behavior, or impulse control.
Tell your healthcare provider if you or someone close to you notices unusual behavior, strong urges that are difficult to control, confusion, or other significant changes while you are taking the medication.
Take Dostinex exactly as prescribed and keep all recommended follow-up appointments. Contact your healthcare provider if you experience severe dizziness, fainting, breathing problems, chest discomfort, swelling, or other unusual symptoms.
If you are pregnant, planning to become pregnant, or think you may be pregnant, tell your healthcare provider before taking Dostinex. The current prescribing information does not state that Dostinex must never be used during pregnancy. Instead, your healthcare provider should consider the possible benefits and risks and decide whether treatment is appropriate for you. Pregnancy-related high blood pressure, such as preeclampsia, can increase safety concerns with cabergoline.
Dostinex begins lowering prolactin levels after treatment starts, but the amount of time needed to reach a normal prolactin level can vary. Your healthcare provider will usually monitor your prolactin with blood tests and adjust your dose gradually if needed. Dose increases are generally made no more often than every 4 weeks. Dostinex is currently approved in the U.S. for high prolactin levels in adults, not for Parkinson’s disease.
Yes. Dostinex can be taken with or without food. If the medicine causes nausea or stomach discomfort, ask your healthcare provider whether taking it with food may make it easier to tolerate.
Dostinex is not considered an addictive medication in the usual sense. However, cabergoline can sometimes cause changes in behavior or strong urges in some people. Take it only as prescribed and tell your healthcare provider about any unusual changes in behavior.
The safety and effectiveness of Dostinex have not been established in children. The current prescribing information states that cabergoline is used to treat hyperprolactinemia in adults. Therefore, the statement that it is simply “not approved under age 16” is too specific. A healthcare provider should determine whether cabergoline is appropriate if treatment is being considered for a child.
Store Dostinex at room temperature, according to the storage instructions on the prescription label. Keep the tablets in their original container and protect them from excessive moisture and heat. Keep Dostinex and all medicines out of the reach of children.
| Generic name: | Cabergoline |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 0.5mg, 1mg |
| Quantities Available: | 8, 16, 20, 24 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Dostinex (cabergoline) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Dostinex is commonly prescribed in dosage of 0.5 mg, taken twice weekly. For a 90-day supply, this means you would order 24 tablets (12 weeks x 2 tablets per week).
Yes, we sell cabergoline on our website! You can enjoy competitive prices on this medication by ordering from us. To place an order, you will need a valid prescription from your healthcare provider. We require this to ensure the safe and accurate dispensing of medications. You can conveniently submit your prescription by mail, fax, or by uploading it through your online account.
Yes, we ship Dostinex (cabergoline) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Dostinex (Cabergoline). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Dostinex (Cabergoline).
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