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Formulation: Vaginal Ring
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Prescription Required
Formulation: Vaginal Ring
Select the quantity to see the price.
* This price includes a dispensing fee, medical review fee, and packing fee.
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Estring contains estradiol hemihydrate, a form of estrogen. It is a prescription vaginal ring used to treat moderate to severe symptoms of atrophic vaginitis caused by menopause.
The ring is placed inside the vagina, where it slowly releases a small amount of estradiol over time. This allows estrogen to act directly on the vaginal tissues that have become dry, thin, or irritated.
After menopause, the body produces much less estrogen. Estrogen normally helps keep the vaginal tissues thick, moist, flexible, and healthy.
When estrogen levels fall, the vaginal lining may become thinner and drier. The tissues can also lose elasticity and become more sensitive to friction or irritation.
These changes are commonly referred to as vaginal atrophy or atrophic vaginitis.
Atrophic vaginitis can cause several uncomfortable symptoms, including vaginal dryness, itching, burning, irritation, soreness, and discomfort during sexual activity.
Some people may also notice that the vaginal tissues feel more delicate or sensitive than before menopause.
Estring helps improve these symptoms by restoring some of the estrogen activity that has been lost.
Estring belongs to a class of medications called estrogens.
Once the ring is placed inside the vagina, it releases estradiol gradually. The estradiol binds to estrogen receptors in the vaginal tissues and helps support normal tissue growth, moisture, and blood flow.
This can help the vaginal lining become healthier, thicker, and more flexible.
Low estrogen levels can reduce natural vaginal moisture and make the tissues feel dry or tight.
By replacing some of the missing estrogen locally, Estring can help improve vaginal moisture and lubrication. This may reduce dryness and make everyday activities and sexual activity more comfortable.
Thin, dry vaginal tissues can become easily irritated and may cause itching, burning, or soreness.
Estradiol helps strengthen and restore the vaginal lining, making it less fragile and less likely to become irritated.
As treatment continues, symptoms such as itching, burning, and discomfort may gradually improve.
Vaginal dryness and thinning can make sexual activity uncomfortable or painful.
By improving moisture, elasticity, and tissue thickness, Estring may help reduce pain or discomfort during intercourse related to menopausal vaginal changes.
Estring is designed to stay inside the vagina and release estradiol slowly over an extended period.
This means you do not need to apply medication every day. The ring provides a steady, local source of estrogen to the vaginal tissues.
Although Estring mainly works locally, some estrogen can still be absorbed into the bloodstream. For this reason, it should be used exactly as prescribed by your healthcare provider.
With regular use, Estring may help reduce:
The amount of improvement can vary from person to person.
Improvement may occur gradually rather than immediately. Some symptoms may start to improve within the first few weeks, while others may take longer.
Continue using Estring exactly as directed by your healthcare provider, even if you do not notice immediate improvement.
Estring helps control vaginal symptoms caused by low estrogen levels, but it does not reverse menopause.
Symptoms may return after treatment is stopped. Your healthcare provider will decide how long you should continue using Estring based on your symptoms, response to treatment, and overall health.
Estring is a soft, flexible vaginal ring that contains estradiol. It is placed inside the vagina, where it slowly releases a small amount of estrogen over time.
The ring is designed to remain in place continuously for 90 days. After that, it should be removed and replaced with a new ring if your healthcare provider wants you to continue treatment.
Before inserting or removing Estring, wash your hands thoroughly with soap and water and dry them well.
Clean hands help reduce the chance of introducing bacteria into the vaginal area.
Open the package and remove Estring from its protective pouch.
Hold the ring between your thumb and index finger. Gently press the sides together so the ring becomes narrower and easier to insert.
Choose a position that allows you to relax your pelvic muscles.
You may lie on your back with your knees bent, squat, or stand with one leg raised on a chair or stool. Use whichever position feels easiest and most comfortable.
Using your fingers, gently guide the compressed ring into the vagina.
Push it upward and backward as far as is comfortable. Estring does not need to be placed in one exact location. It simply needs to sit high enough inside the vagina that it stays in place comfortably.
Do not force the ring if you feel pain or strong resistance.
When Estring is positioned correctly, you usually should not feel it during normal daily activities.
If you can feel the ring near the vaginal opening or notice mild pressure or discomfort, it may not be inserted far enough. Wash your hands and use a clean finger to gently push the ring higher into the vagina.
If discomfort continues after repositioning the ring, contact your healthcare provider.
Estring should remain inside the vagina continuously for 90 days.
During this time, it gradually releases estradiol into the vaginal tissues. You do not need to remove and reinsert it every day.
At the end of 90 days, the old ring should be removed. If treatment is continuing, replace it with a new Estring as directed by your healthcare provider.
You can usually leave Estring in place while walking, exercising, bathing, showering, sleeping, and performing other normal activities.
Because it is designed for continuous use, there is generally no need to remove it during your daily routine.
Estring can usually remain in place during sexual intercourse.
Some people or their partners may occasionally notice the ring, but it should not normally interfere with sexual activity. If the ring causes discomfort, talk to your healthcare provider about the best way to manage it.
The ring may occasionally shift lower in the vagina, especially during straining or bowel movements.
If you can feel it near the vaginal opening, use a clean finger to gently push it back upward.
If the ring repeatedly moves out of position, contact your healthcare provider.
Estring may occasionally fall completely out of the vagina.
If this happens, rinse the ring with lukewarm water, then reinsert it using the same gentle technique. Avoid using hot or boiling water.
If the ring falls out frequently or you are unable to keep it in place, contact your healthcare provider.
After 90 days, wash and dry your hands before removing the ring.
Insert a finger into the vagina and hook it through the center of the ring or around its lower edge. Gently pull downward and outward until the ring comes out.
If removal is difficult or painful, do not force it. Contact your healthcare provider for assistance.
If your healthcare provider wants you to continue treatment, insert a new Estring after removing the old one.
Keeping track of the replacement date can help ensure the ring is not left in place longer than recommended.
Estring is designed to provide medication for about 90 days.
Leaving the same ring in longer than recommended may mean you are no longer receiving the intended amount of estradiol. Replace it on schedule unless your healthcare provider gives you different instructions.
Contact your healthcare provider if you experience persistent vaginal pain, unusual bleeding, severe irritation, repeated ring expulsion, difficulty inserting or removing the ring, or other symptoms that concern you.
Your healthcare provider can check whether Estring is positioned properly and determine whether the treatment remains appropriate for you.
Estring (Estradiol Hemihydrate) is available in the following forms and strength:
Tell your healthcare provider if you have a history of high blood pressure, heart disease, blood clots, stroke, or heart attack before using Estring.
Estrogen therapy may increase the risk of blood clots and certain cardiovascular problems in some people, especially if other risk factors are present.
Estring should not be used during pregnancy.
If you are breastfeeding, talk to your healthcare provider before using Estring. Estradiol can pass into breast milk and may also affect milk production.
Do not use Estring if you are allergic to estradiol or any other ingredient in the vaginal ring.
Seek medical attention if you develop signs of a serious allergic reaction, such as swelling, hives, or difficulty breathing.
Estrogen can stimulate the lining of the uterus. In women who still have a uterus, long-term estrogen use may increase the risk of endometrial hyperplasia, which is abnormal thickening of the uterine lining, and may also increase the risk of endometrial cancer.
Your healthcare provider will consider your individual risk factors and may recommend additional treatment or monitoring when needed.
Use Estring with caution if you have a history of gallbladder disease, liver problems, or jaundice.
Estrogen may worsen certain liver or gallbladder conditions, so tell your healthcare provider about any past or current problems before starting treatment.
Some forms of estrogen therapy have been associated with an increased risk of probable dementia in women 65 years of age and older.
The risks can vary depending on the type of estrogen treatment, dose, duration, and individual health factors. Your healthcare provider will determine whether Estring is appropriate for you.
Tell your healthcare provider if you experience unexpected vaginal bleeding or spotting while using Estring.
Unexplained bleeding should be evaluated because it may be related to changes in the uterine lining or another medical condition.
Store Estring at room temperature, away from excessive heat and moisture.
Keep it in a safe place and out of reach of children and pets until you are ready to use it.
Your healthcare provider will consider your symptoms, medical history, current medications, and overall health before deciding whether Estring is appropriate for you. They may also review factors such as your history of blood clots, certain cancers, liver problems, unexplained vaginal bleeding, and other conditions that can affect the safety of estrogen treatment.
Yes. Estring may be used by women who have had a hysterectomy if they have menopausal vaginal symptoms that may benefit from local estrogen treatment. Because the uterus has been removed, concerns related to stimulation of the uterine lining are generally different from those in women who still have a uterus. Your healthcare provider will still consider your overall health and estrogen-related risk factors.
You should have regular medical follow-up while using Estring. Your healthcare provider may recommend pelvic exams, breast exams, mammograms, or other monitoring based on your age, health history, symptoms, and how long you have been using estrogen therapy. Report any new symptoms, especially unusual vaginal bleeding, breast changes, pelvic pain, or persistent vaginal irritation.
Estring begins releasing estradiol after it is inserted, but improvement in symptoms may develop gradually. Some people may notice less dryness, irritation, or discomfort within the first few weeks, while others may need more time to experience the full benefit. Continue using Estring as directed even if improvement is not immediate.
Estring should not be used during pregnancy. If you are breastfeeding, talk to your healthcare provider before using Estring. Estradiol can pass into breast milk and may also affect milk production.
Store Estring at room temperature, away from excessive heat and moisture. Keep the ring in its original pouch until you are ready to use it, and store it out of reach of children and pets.
| Generic name: | Estradiol Hemihydrate |
|---|---|
| Formulation: | Vaginal Ring |
| Strength(s): | 2mg |
| Quantities Available: | 1 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Estring (estradiol hemihydrate) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time. This allows for continuous use without the need for frequent refills, ensuring consistent management of your prescription medication.
Here’s what you need to know:
Dosage and Quantity: Estring is typically prescribed as one ring containing 2 mg of estradiol, which is replaced every three months. For a 90-day supply, you would order 1 ring.
No, we do not sell estradiol hemihydrate separately on our website. However, you can still enjoy low prices on Estring, which contains estradiol hemihydrate as an active ingredient. Please note that you will need a valid prescription from your healthcare provider to purchase Estring. We require this prescription to dispense the medication, and you have the option to mail, fax, or upload your prescription through your online account for processing.
Yes, we ship Estring (estradiol hemihydrate) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Estring (Estradiol Hemihydrate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Estring (Estradiol Hemihydrate).
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