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Formulation: Capsule
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Prescription Required
Formulation: Capsule
(Generic Alternative)
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Deplin (active ingredient: L-methylfolate) is a prescription medical food used under the supervision of a healthcare provider. It is commonly prescribed as an adjunctive (add-on) treatment for adults with major depressive disorder (MDD) who have not experienced an adequate response to antidepressant medication alone.
Unlike standard folic acid supplements, Deplin contains L-methylfolate, the biologically active form of folate that the body can use immediately.
Deplin is used as an add-on treatment for adults with major depressive disorder (MDD) who continue to have symptoms despite taking an antidepressant.
Some people may have difficulty converting folic acid into its active form. Deplin provides the active form directly, helping ensure the body has enough L-methylfolate to support normal brain function.
It is not intended to replace antidepressant medication but may help improve treatment response when used alongside other prescribed therapies.
Deplin belongs to a category of products known as medical foods. It provides L-methylfolate, the active form of folate that plays an important role in the production of neurotransmitters involved in mood regulation.
L-methylfolate helps support the production of important brain chemicals, including:
These neurotransmitters help regulate mood, emotions, and cognitive function. By supplying the active form of folate, Deplin may help optimize neurotransmitter production and enhance the effectiveness of antidepressant therapy in some individuals.
When used as prescribed, Deplin may help:
Deplin should only be used under the supervision of a healthcare provider. Continue taking all medications exactly as prescribed, and do not stop or change your antidepressant treatment unless directed by your healthcare provider.
Deplin is available as an oral capsule and should be taken exactly as prescribed by your healthcare provider. It is a prescription medical food intended to be used under medical supervision as part of the dietary management of depression and schizophrenia.
Take one capsule each day, or as directed by your healthcare provider. To help you remember your dose, try taking it at the same time every day. Do not change your dose or stop taking Deplin unless instructed by your healthcare provider.
The dosage of Deplin depends on:
For adults and children 12 years of age and older, the recommended dosage is:
Deplin is available in two strengths:
Your healthcare provider will determine which strength is most appropriate for your individual needs.
Because nutritional needs vary from person to person, your healthcare provider will determine the most appropriate dose and treatment plan for your individual condition.
Deplin (L-Methylfolate) is available in the following forms and strength:
Before taking Deplin, tell your healthcare provider about your medical history, allergies, and all medications you are taking. Although Deplin is generally well tolerated, it should only be used under the supervision of a healthcare provider as part of your treatment plan.
Deplin is a prescription medical food, not a dietary supplement or traditional medication. It is intended to meet the distinctive nutritional requirements associated with neurotransmitter imbalances in the dietary management of depression and schizophrenia and should only be used under medical supervision.
Do not take Deplin if you are allergic to L-methylfolate or any of its ingredients.
Seek immediate medical attention if you develop symptoms of an allergic reaction, such as:
Although allergic reactions are uncommon, they have been reported with oral L-methylfolate products.
If you have bipolar disorder or a history of manic episodes, tell your healthcare provider before starting Deplin.
People with depression should be evaluated for bipolar disorder before beginning treatment, as improving neurotransmitter activity may contribute to mood elevation or trigger a manic episode in susceptible individuals.
Tell your healthcare provider if you have a history of vitamin B12 deficiency or pernicious anemia.
Folate therapy alone is not an appropriate treatment for vitamin B12 deficiency. Your healthcare provider may recommend testing or monitoring your vitamin B12 levels before and during treatment.
Before taking Deplin, provide your healthcare provider with a complete list of all the medications and supplements you use.
Certain medications may affect folate levels or interact with L-methylfolate, including:
Your healthcare provider can determine whether any additional monitoring or treatment adjustments are needed.
If you are pregnant, planning to become pregnant, or breastfeeding, tell your healthcare provider before taking Deplin.
Your healthcare provider will determine whether Deplin is appropriate for you based on your individual nutritional needs and overall treatment plan.
Contact your healthcare provider if you experience:
Regular follow-up appointments allow your healthcare provider to monitor your progress and determine whether Deplin continues to meet your nutritional and treatment needs.
Deplin contains L-methylfolate, the active form of folate that your body can use immediately. L-methylfolate helps support the production of important neurotransmitters, including serotonin, dopamine, and norepinephrine, which play key roles in regulating mood. Deplin is prescribed as a medical food to help manage the nutritional needs associated with depression and is typically used alongside antidepressant medication rather than as a replacement.
The time it takes for Deplin to work varies from person to person. Some people may notice improvements within several weeks, while others may take longer to experience the full benefits. Continue taking Deplin exactly as prescribed and do not stop treatment without consulting your healthcare provider.
Yes. Deplin is commonly prescribed along with antidepressant medications for adults with major depressive disorder who have not had an adequate response to antidepressants alone. It is intended to complement—not replace—your prescribed antidepressant therapy.
Deplin is neither a standard vitamin supplement nor a traditional prescription medication. It is a prescription medical food that contains L-methylfolate, the biologically active form of folate. It is specially formulated to meet the distinctive nutritional requirements associated with certain medical conditions and should be used only under the supervision of a healthcare provider.
If you miss a dose of Deplin, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time or take extra capsules to make up for a missed dose. If you are unsure what to do after missing a dose, contact your healthcare provider or pharmacist for advice.
Do not stop taking Deplin without first speaking with your healthcare provider. Your provider will determine how long you should continue treatment based on your symptoms, overall treatment plan, and response to therapy.
Yes. Deplin is available by prescription only. Although it contains L-methylfolate, it is classified as a prescription medical food and should only be used under the supervision of a healthcare provider.
In many cases, Deplin can be taken with other vitamins or supplements. However, you should always tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, herbal supplements, and natural health products you take to help avoid potential interactions or unnecessary duplication of folate intake.
| Generic name: | L-Methylfolate |
|---|---|
| Formulation: | Capsule, Tablet |
| Strength(s): | 7.5mg, 15mg |
| Quantities Available: | 90 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Deplin (L-methylfolate) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Deplin is commonly prescribed in dosages of 7.5 mg or 15 mg, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).
Yes, we do sell L-methylfolate. You can enjoy low prices on this medication. To purchase L-methylfolate, you will need a valid prescription from your healthcare provider. We require this to dispense the medication. You can submit your prescription by mailing, faxing, or uploading it through your online account.
Yes, we ship Deplin (L-methylfolate) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Deplin (L-Methylfolate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Deplin (L-Methylfolate).
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