Prescription Required
Formulation: Eye Drops
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Prescription Required
Formulation: Eye Drops
(Generic Alternative)
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Combigan is a prescription eye drop that contains two active ingredients:
It is used to help lower intraocular pressure (IOP), which is the pressure inside the eye. Elevated eye pressure can damage the optic nerve and increase the risk of vision loss if left untreated.
Combigan combines two medications that work together to provide greater pressure reduction than either medication alone.
Open-Angle Glaucoma
Combigan is commonly prescribed for people with open-angle glaucoma, the most common form of glaucoma.
Open-angle glaucoma develops when fluid inside the eye does not drain properly, causing pressure to build up over time. Increased eye pressure can gradually damage the optic nerve and lead to permanent vision loss if not adequately controlled.
Ocular Hypertension
Combigan is also used to treat ocular hypertension, a condition in which pressure inside the eye is higher than normal but optic nerve damage has not yet occurred.
Lowering eye pressure may help reduce the risk of developing glaucoma and protect long-term vision.
When Other Treatments Are Not Enough
Combigan is typically prescribed when treatment with a single medication (monotherapy) does not adequately control eye pressure. By combining two different medications in one eye drop, Combigan may provide more effective pressure reduction.
Combigan contains two medications that lower eye pressure through complementary mechanisms.
Brimonidine Tartrate (Alpha Agonist)
Brimonidine belongs to a class of medications called alpha-adrenergic agonists.
It helps lower eye pressure by:
This helps decrease pressure within the eye and reduces stress on the optic nerve.
Timolol Maleate (Beta Blocker)
Timolol belongs to a class of medications known as beta blockers.
It works by:
With less fluid being produced, pressure inside the eye is reduced.
Dual Action for Better Pressure Control
By combining brimonidine and timolol, Combigan helps lower intraocular pressure through two different mechanisms:
This dual-action approach can provide more effective control of eye pressure than either medication alone.
When used as prescribed, Combigan may help:
Combigan helps control eye pressure but does not cure glaucoma or ocular hypertension. Regular use and routine eye examinations are important to help protect your vision and monitor your response to treatment.
Combigan is an ophthalmic (eye drop) solution that contains brimonidine tartrate 0.2% and timolol maleate 0.5%. It is applied directly into the eye to help lower intraocular pressure in patients with glaucoma or ocular hypertension.
Combigan is available in several bottle sizes, including 5 mL, 10 mL, and 15 mL. Always use the medication exactly as prescribed by your healthcare provider.
The usual dosage of Combigan is:
Using the medication at the same times each day can help maintain consistent control of eye pressure.
To use Combigan properly:
To help prevent contamination, do not allow the tip of the dropper bottle to touch your eye, fingers, or any other surface.
If you wear contact lenses:
This helps prevent the medication or preservatives in the solution from being absorbed by the lenses.
If you use additional eye drops or ophthalmic medications:
This helps ensure that each medication is properly absorbed and reduces the chance of one medication washing out the other.
Regular eye examinations and consistent use of your medication are important to help protect your vision and control eye pressure effectively.
Combigan (Brimonidine Tartrate/Timolol Maleate) is available in the following forms and strengths:
Before using Combigan, discuss your medical history and all medications you are taking with your healthcare provider. Following proper administration instructions can help maximize the effectiveness of the medication and reduce the risk of side effects.
Use Combigan exactly as prescribed by your healthcare provider. Do not change your dosage, stop treatment, or use the medication more often than directed without first consulting your healthcare provider, even if you believe a different dose may be more appropriate.
Store Combigan at room temperature and protect it from excessive heat, moisture, and direct light.
To help maintain the quality of the medication:
To reduce the risk of eye infections or contamination:
Always replace the cap securely after each use.
If you use other ophthalmic medications, wait at least 10 minutes between applications.
This helps ensure each medication is absorbed properly and prevents one eye drop from washing out another.
If you wear soft contact lenses:
This helps prevent the medication or preservatives from being absorbed into the lenses.
Use caution when taking Combigan with certain medications, including:
These combinations may increase the risk of side effects or affect how the medications work. Be sure to provide your healthcare provider with a complete list of all prescription medications, over-the-counter products, vitamins, and supplements you use.
Because Combigan contains timolol, a beta blocker, it may occasionally cause serious respiratory or cardiovascular side effects in susceptible individuals.
Tell your healthcare provider if you have a history of:
Seek medical attention if you experience:
Combigan should be used with caution in people with a history of depression or certain mood disorders. Inform your healthcare provider if you have experienced depression or other mental health conditions in the past.
Combigan must not be used in infants younger than 2 years of age.
In general, Combigan is not routinely recommended for children and adolescents between 2 and 17 years of age, unless specifically prescribed and closely monitored by a healthcare provider.
Contact your healthcare provider if you experience:
Any unusual or severe side effects
Regular eye examinations and follow-up appointments are important to ensure Combigan is working safely and effectively to control your eye pressure.
You should follow your healthcare provider’s instructions regarding how long to use Combigan. Once a bottle has been opened, any remaining solution should generally be discarded 4 weeks after opening. Combigan contains a preservative that helps prevent bacterial contamination after the bottle is opened, but over time the preservative may become less effective, increasing the risk of contamination and potential eye infections. To help ensure safe use, write the date you opened the bottle on the carton or label, discard any unused solution after 4 weeks, and never use expired eye drops. Proper storage and timely disposal can help maintain the safety and effectiveness of the medication.
Combigan may not be appropriate for everyone. You should not use Combigan if you have asthma, chronic obstructive pulmonary disease (COPD), certain serious heart conditions, severe heart failure, specific heart rhythm disorders such as AV block, or a history of slow heartbeats that have caused fainting. Because Combigan contains timolol, a beta blocker, it may worsen certain breathing and heart conditions. In addition, Combigan should not be used in children younger than 2 years of age. Before starting treatment, be sure to inform your healthcare provider about your complete medical history, including any heart, lung, or other medical conditions, so they can determine whether Combigan is safe and appropriate for you.
The usual recommended dosage of Combigan is one drop in the affected eye(s) twice daily, administered approximately 12 hours apart. Many people use Combigan once in the morning and once in the evening to help maintain consistent control of intraocular pressure throughout the day. Always use the medication exactly as prescribed by your healthcare provider and do not change your dosing schedule without their guidance.
If you miss a dose of Combigan, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not use extra drops, apply two doses at the same time, or double your dose to make up for a missed one. If you are unsure what to do after missing a dose, contact your healthcare provider or pharmacist for guidance.
| Generic name: | Brimonidine Tartrate/Timolol Maleate |
|---|---|
| Formulation: | Eye Drops |
| Strength(s): | 0.2/0.5% |
| Quantities Available: | 5mL, 10mL, 15mL, 20mL |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Combigan (brimonidine tartrate/timolol maleate) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard for many prescription medications to ensure continuous treatment without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Combigan comes in a strength of 0.2/0.5% and is typically prescribed with one drop applied to the affected eye(s) twice daily. For a 90-day supply, it would require 180 drops (90 days x 2 drops per day).
Yes, we do sell brimonidine tartrate/timolol maleate on our website. You can enjoy low prices when purchasing this medication. However, please note that you will need a valid prescription from your healthcare provider in order to make a purchase. We require this prescription to dispense the medication safely and legally. You can conveniently provide your prescription by mailing, faxing, or uploading it through your online account on our website.
Yes, we ship (brimonidine tartrate/timolol maleate) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Combigan (Brimonidine Tartrate/Timolol Maleate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Combigan (Brimonidine Tartrate/Timolol Maleate).
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