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Agrylin contains the active ingredient anagrelide. It is a prescription medication used to lower high platelet levels in people with certain blood disorders.
Agrylin is used to treat essential thrombocythemia, a condition in which the bone marrow makes too many platelets.
Having too many platelets can increase the risk of:
Agrylin helps lower the platelet count and may reduce the risk of complications linked to very high platelet levels.
Agrylin belongs to a group of medications called platelet-reducing agents.
It works mainly by slowing the development of megakaryocytes, the bone marrow cells that produce platelets.
This helps reduce the number of platelets in the blood.
Agrylin helps control high platelet levels, but it does not cure the underlying blood disorder.
Your healthcare provider will usually monitor your platelet count and other blood tests during treatment to make sure the medication is working safely.
Agrylin is taken by mouth as a capsule.
It may be taken with or without food. Swallow the capsule whole with water.
Take Agrylin exactly as prescribed and try to take your doses at the same times each day.
The usual adult starting dose is either:
Your healthcare provider will choose the schedule that is most appropriate for you.
Your dose is adjusted according to your platelet count and how well you tolerate the medication.
Dose increases are usually made slowly, generally no more than 0.5 mg per day during any one-week period.
Your healthcare provider will order regular blood tests to help determine the best dose for you.
The maximum recommended dose is generally 10 mg per day.
A single dose should not usually be more than 2.5 mg.
Do not increase your dose on your own.
Tell your healthcare provider if you have liver disease.
People with liver impairment may need a lower starting dose and closer monitoring because anagrelide is processed by the liver.
Agrylin may be used in some children with high platelet counts, but treatment should be closely supervised by a specialist.
The dose is individualized according to the child’s condition and response to treatment.
If you miss a dose of Agrylin, take it as soon as you remember.
If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule.
Do not take two doses at the same time or take extra capsules to make up for a missed dose.
Continue taking Agrylin even if you feel well.
The medication helps control your platelet count, and stopping treatment may cause your platelet level to rise again.
Do not stop taking Agrylin or change your dose without speaking with your healthcare provider.
Your healthcare provider will check your platelet count regularly, especially when treatment begins or your dose changes.
These tests help make sure your platelet count is decreasing safely and that your dose remains appropriate.
Agrylin (Anagrelide) is available in the following forms and strength:
Agrylin can affect the heart and may increase heart rate or change the heart’s electrical rhythm.
Serious heart problems such as QT prolongation, ventricular tachycardia, palpitations, and heart failure have been reported.
Before starting treatment, your healthcare provider may check your heart with an ECG.
Tell your healthcare provider right away if you develop:
People with existing heart disease may need closer monitoring.
Rarely, Agrylin may cause pulmonary hypertension, which is high blood pressure in the blood vessels of the lungs.
Contact your healthcare provider if you develop:
Your healthcare provider may assess your heart and lung health before and during treatment.
Agrylin lowers platelet levels, so it can increase the risk of bleeding.
The risk may be higher if you also take medications that affect blood clotting, such as:
Contact your healthcare provider if you notice unusual bruising, nosebleeds, blood in your urine, black stools, or vomiting blood.
Tell your healthcare provider if you have liver disease.
Liver impairment can increase the amount of anagrelide in your body and may raise the risk of heart-related side effects.
People with moderate liver impairment usually need a lower starting dose. Agrylin should generally be avoided in severe liver impairment.
Tell your healthcare provider if you have kidney disease.
Kidney problems do not automatically prevent you from using Agrylin, but your healthcare provider may monitor your overall health and laboratory results more closely.
Agrylin may cause dizziness or lightheadedness.
Avoid driving, operating machinery, or doing activities that require alertness until you know how the medication affects you.
Agrylin may cause swelling, especially in the legs or ankles.
Tell your healthcare provider if you develop new or worsening swelling, rapid weight gain, or shortness of breath because these symptoms may also be signs of a heart problem.
Tell your healthcare provider if you are pregnant or planning to become pregnant.
Your healthcare provider will consider the expected benefits and possible risks before recommending Agrylin during pregnancy.
Tell your healthcare provider if you are breastfeeding.
Your healthcare provider will help decide whether Agrylin or breastfeeding should be continued based on your treatment needs.
Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, and supplements you take.
Agrylin may interact with medications that:
Some combinations may increase the risk of serious side effects.
Your healthcare provider will check your platelet count regularly during treatment.
Your dose may need to be adjusted if your platelet count becomes too low or does not decrease enough.
Contact your healthcare provider right away if you develop chest pain, an irregular heartbeat, fainting, severe shortness of breath, unusual bleeding, or significant swelling while taking Agrylin.
If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time or take extra capsules to make up for a missed dose.
Agrylin may begin lowering your platelet count within the first several days of treatment, but it can take a few weeks to reach the target platelet level. Your healthcare provider will check your platelet count regularly and may adjust your dose based on your response.
No. Agrylin does not cure essential thrombocythemia. It helps lower and control the number of platelets in your blood, which may reduce the risk of complications linked to very high platelet levels. Continue taking it as prescribed, even if your platelet count improves.
Alcohol may increase side effects such as dizziness or lightheadedness. It is best to limit or avoid alcohol until you know how Agrylin affects you. Ask your healthcare provider whether alcohol is safe for you based on your other medications and health conditions.
| Generic name: | Anagrelide |
|---|---|
| Formulation: | Capsule |
| Strength(s): | 0.5mg |
| Quantities Available: | 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Agrylin (anagrelide) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Agrylin is commonly prescribed in dosages of 0.5 mg, taken multiple times daily. For example, if your prescribed dosage is 0.5 mg twice daily, then for a 90-day supply, you would order 180 capsules (90 days x 2 capsules per day).
Yes, we do sell anagrelide on our website. You can enjoy low prices on this medication. To purchase anagrelide, you will need a valid prescription from your healthcare provider. We require this to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account.
Yes, we ship Agrylin (anagrelide) to both the United States and Puerto Rico.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Agrylin (Anagrelide). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Agrylin (Anagrelide).
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