Zylet (Tobramycin/ Loteprednol etabonate)

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Zylet Brand
Dosage Quantity & Price
Tobramycin/ Loteprednol etabonate (Generic alternate to Zylet) Generic

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Table of contents:

Zylet is a prescription medication prescribed to treat certain inflammatory eye conditions that have either a confirmed or suspected bacterial infection. It contains the active ingredients loteprednol and tobramycin in ophthalmic suspension form.

The loteprednol in Zylet is a corticosteroid and works by inhibiting processes in the body that cause inflammation, while tobramycin is an antibiotic that works by stopping the growth of bacteria. Zylet is available under prescription only and should not be used without consulting a doctor.

Uses and Dosage

The dosage and frequency of use for Zylet suspension drops can be tailored to your specific condition and your doctor's evaluation. The recommended daily dosage is one or two drops of the ophthalmic solution, to be administered four to six hours apart. During the first day or two of treatment, your healthcare provider may advise a more frequent dosage, with drops administered every one to two hours.

Do not exceed or change the recommended dosage without consulting your doctor, as this can reduce the effectiveness of the medication and increase the risk of side effects.

To use Zylet suspension drops, follow these steps:

  1. Wash your hands thoroughly before handling the medication.
  2. Shake the bottle well before using it.
  3. Tilt your head back and pull down your lower eyelid to create a small pocket.
  4. Hold the bottle upside down and use your other hand to gently pull down your lower eyelid further, forming a bigger pocket.
  5. Without touching your eye or eyelid with the tip of the dropper, instill the prescribed number of drops into the pocket.
  6. Release your lower eyelid and close your eyes gently for a few seconds.
  7. If you are using the medication in both eyes, repeat steps 3-6 for the other eye.
  8. After using the medication, replace the cap firmly on the bottle.

Use Zylet exactly as prescribed by your healthcare provider. If you have any questions or concerns about how to use this medication, be sure to speak with your doctor or pharmacist.

Side effect

Common Side Effects of Zylet (Tobramycin/ Loteprednol etabonate):

  • Headache
  • Light sensitivity
  • Minor burning, stinging, or irritation after administering drops
  • Puffiness
  • Watery eyes

Serious Side Effects of Zylet (Tobramycin/ Loteprednol etabonate):

  • Blurry vision
  • Cloudy vision
  • Crusting around the eyes
  • Eye pain
  • Eye swelling
  • Seeing halos around lights
  • Severe discomfort
  • Severe pain or irritation

Form and Strength

Zylet (Tobramycin/ Loteprednol etabonate) is available in the following forms and strength:

Zylet: Eye drops suspension

  • 0.3%/0.5%


  • Prolonged use of corticosteroids like loteprednol in Zylet may cause increased intraocular pressure, which can lead to glaucoma and optic nerve damage.
  • Concurrent use with other eye medications should be used with caution and under the direction of a doctor.
  • Use of Zylet should be avoided during viral infections of the eye, such as herpes simplex, and in fungal or mycobacterial infections.
  • Zylet should be used with care in individuals with a history of severe allergic reactions or hypersensitivity reactions to antibiotics or corticosteroids.
  • The use of Zylet may temporarily affect visual acuity and patients should wait until their vision clears before driving or operating machinery.
  • Zylet should not be used during pregnancy or breastfeeding without first consulting with a doctor.
  • Zylet may cause adverse reactions such as burning, itching, redness, or swelling of the eye. If these reactions persist or worsen, a doctor should be consulted.
  • Long-term use of Zylet may increase the risk of other eye infections or fungal infections.
  • Zylet should be used with caution in patients with a history of any eye discomfort, blurred vision, or other visual problems.
  • Patients should not use contact lenses while using Zylet unless otherwise directed by a doctor.

Frequently Asked Questions (FAQ)

How many days should you use Zylet?

Do not use this medication more often than prescribed or for longer than 2 weeks unless directed by your doctor. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

How long does it take for Zylet to work?

It may take several days, up to a week or more for Zylet to work. However, the exact amount of time it takes may vary depending on the individual and the severity of the condition being treated.

How should Zylet be stored?

Zylet should be stored in a cool, dry place and away from sunlight. It should also be kept out of the reach of children and pets.

Can I wear contact lenses while using Zylet?

Patients should not use contact lenses while using Zylet unless otherwise directed by a doctor.

What should I do if I miss a dose of Zylet?

If you miss a dose of Zylet, you should apply it as soon as you remember. However, if it is close to the time for the next dose, you should skip the missed dose and resume your normal dosing schedule.


It's important to purchase Zylet from verified Canadian pharmacy.

Additional information

Generic name:

Tobramycin/ Loteprednol etabonate


Eye drops suspension



Quantities Available:

5mL, 10mL


Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Zylet (Tobramycin/ Loteprednol etabonate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Zylet (Tobramycin/ Loteprednol etabonate).