Indications
Tivicay (active ingredient: dolutegravir) is a prescription medication indicated for:
- HIV-1 Infection: Tivicay is used in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and pediatric patients weighing at least 30 kg (66 lbs).
Tivicay belongs to a class of drugs known as integrase strand transfer inhibitors (INSTIs), which work by blocking the action of the integrase enzyme, thereby preventing the integration of the HIV-1 viral genome into the host cell DNA and inhibiting viral replication.
Uses and Dosage
The proper use of Tivicay tablet should be determined by a healthcare provider, but generally it is taken orally once daily with or without food, preferably at the same time each day. The tablet should be swallowed whole, and not crushed or chewed. The dosage may vary depending on individual factors such as age, weight, and medical history, and should be determined by a healthcare provider. Continue regular follow-up appointments to monitor the safety and effectiveness of the medication, and to report any side effects or concerns to a healthcare provider promptly.
The dosage of Tivicay can vary depending on individual factors such as age, weight, and medical history, and should be determined by a healthcare provider. However, the recommended dosage for adults is typically 50 mg once/twice daily, with or without food.
Side effect
Common Side Effects of Tivicay (Dolutegravir Sodium):
- Decreased frequency or amount of urine
- Discharge or excessive tearing
- Headache
- Hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
- Increased thirst.
- Large
- Muscle or joint aches
- Nausea or vomiting
- Tiredness
- Trouble sleeping
Serious Side Effects of Tivicay (Dolutegravir Sodium):
- Blisters or peeling of the skin
- Blisters or sores in mouth
- Dark or “tea-colored” urine
- Fever
- Generally ill feeling
- Light-colored stools (bowel movements)
- Loss of appetite
- Pain, aching, or tenderness on the right side of your stomach area
- Problems breathing
- Redness or swelling of the eyes
- Swelling of the mouth, face, lips, or tongue
- Your skin or the white part of your eyes turns yellow (jaundice)
Form and strength
Tivicay (Dolutegravir Sodium) is available in the following forms and strength:
Tivicay: Tablet
- 50 mg
Dolutegravir Sodium: Tablet
- 50 mg
Caution
- Tivicay should be used with caution in patients with a history of liver problems, and liver function should be monitored periodically during treatment.
- Tivicay may cause changes in mood or behavior, and patients should report any new or unusual symptoms to their healthcare provider.
- Tivicay may interact with certain medications, supplements, and over-the-counter drugs, inform a healthcare provider about all medications being taken.
- Tivicay may not be effective against all HIV-1 strains, and resistance to the medication may develop if it is not used properly or with adequate support from other medications.
- Before taking dolutegravir, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. It may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
- The caution provided by the medication label is that before using dolutegravir, women of childbearing age should talk with their doctor(s) about the risks and benefits.
Frequently Asked Questions (FAQ)
Can I take Tivicay with food?
Yes, Tivicay can be taken with or without food.
Can pregnant or breastfeeding women take Tivicay?
The safety and effectiveness of Tivicay for pregnant or breastfeeding women have not been established and consult with a healthcare provider before taking the medication.
Is Tivicay a cure for HIV?
Tivicay is not a cure for HIV, but it can help to reduce the amount of virus in the body and slow down the progression of the disease.
How should Tivicay be stored?
Tivicay should be stored at room temperature between 20°C to 25°C (68°F to 77°F) and should be kept in its original container with the lid tightly closed. It should be kept out of the reach of children and pets.
How long does Tivicay take to work?
The effectiveness of Tivicay may vary from person to person, but it usually takes several weeks to months to see a reduction in the amount of the virus in the body.
Resources
- https://www.drugs.com/tivicay.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204790lbl.pdf
- https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=63df5af3-b8ac-4e76-9830-2dbb340af922
- https://www.rxlist.com/tivicay-drug.htm#indications
- https://www.webmd.com/drugs/2/drug-164894-1561/dolutegravir-oral/dolutegravir-oral/details
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