Indications
Salazopyrin is a prescription medication used to treat and manage inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. It can be used to treat inflammatory bowel disease and rheumatoid arthritis. It also helps to keep the immune system from attacking healthy tissue, thereby reducing the symptoms of autoimmune diseases.
Salazopyrin contains sulfasalazine, which exerts immunomodulatory, antibacterial, and anti-inflammatory effects. It works by reducing the body's production of prostaglandins, which are responsible for inflammation and pain. Sulfasalazine is excreted unchanged in the bile and urine.
Use and Dosage
Salazopyrin comes in the form of tablets to take by mouth usually taken at evenly spaced intervals over a 24-hour period. The usual dose is 2 tablets, two to three times a day. The tablet should be swallowed whole after meals with a full glass of water. Do not crush, break, or chew the tablets. Your doctor will determine the proper dose, considering the age and weight of the child.
Take Salazopyrin exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Side Effects
Common Side Effects of Salazopyrin (Sulfasalazine):
- Diarrhea
- Dizziness
- Headache
- Increased sensitivity of skin to sunlight
- Itchiness
- Loss of appetite
- Low sperm count (men)
- Nausea
- Upset stomach
- Vomiting
Serious Side Effects of Salazopyrin (Sulfasalazine):
- Aching joints and muscles
- Difficulty swallowing
- Headache (continuing)
- Signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
- Signs of kidney problems (e.g., increased urination at night, decreased urine production, blood in the urine)
- Signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
- Skin rash, hives, fever
- Symptoms of anemia (such as weakness, paleness, and fatigue)
- Symptoms of arthritis (such as joint pain, stiffness)
- Symptoms of infection (such as fever, chills, or a general feeling of being ill)
- Yellow stain on contact lenses
- Orange-yellow urine
Forms and Strength
Salazopyrin (Sulfasalazine) is available in the following forms and strength:
Salazopyrin: Tablet
- 500 mg
Sulfasalazine: Regular Release Tablet
- 500 mg
Cautions
- Kidney problems: Salazopyrin can affect the kidneys, so drink plenty of fluids while taking Salazopyrin tablet.
- Liver problems: Salazopyrin can cause liver problems in some people, so liver function tests may be required before and during treatment.
- Blood disorders: Salazopyrin can affect blood cell counts, so regular blood tests may be required to monitor for any changes in blood counts.
- Allergic reactions: Some people may be allergic to Salazopyrin, inform your doctor if you have any allergies.
- Pregnancy and breastfeeding: Salazopyrin can be harmful to a developing fetus and can pass into breast milk, so it should be avoided during pregnancy and breastfeeding unless specifically prescribed by a doctor.
- Other medication interactions: Salazopyrin may interact with other medications, including blood thinners and diabetes medications, inform your doctor of all medications you are taking before starting treatment with Salazopyrin.
- Gastrointestinal problems: Salazopyrin can cause gastrointestinal side effects such as nausea, vomiting, and diarrhea.
- Skin reactions: Some people may experience skin reactions such as rashes, itching, and hives while taking Salazopyrin.
- Eye problems: Salazopyrin can cause eye problems such as blurred vision and difficulty focusing.
- Increased risk of infections: Salazopyrin can reduce the body's ability to fight infections, avoid exposure to people who are sick and inform your doctor if you develop any signs of infection.
- Increased risk of cancer: Long-term use of Salazopyrin may increase the risk of certain types of cancer, although this risk is generally low.
Frequently Asked Questions (FAQ)
Can Salazopyrin cause hair loss?
Hair loss is a rare side effect of Salazopyrin, but it can occur in some people.
How long does it take for Salazopyrin to start working?
Salazopyrin can take several weeks to start working and continue taking the medication as prescribed by a doctor.
Can Salazopyrin be stopped suddenly?
Salazopyrin should not be stopped suddenly, as this can cause a flare-up of symptoms. Discuss any changes to your medication regimen with a doctor.
What should I do if I miss a dose of Salazopyrin?
If you miss a dose of Salazopyrin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Is it safe to drink alcohol while taking Salazopyrin?
Alcohol should be avoided while taking Salazopyrin, as it can increase the risk of liver problems and gastrointestinal side effects.
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