Linessa (Desogestrel/Ethinyl Estradiol)

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Linessa Brand
Dosage Quantity & Price
21 day
28 day
Desogestrel/Ethinyl Estradiol (Generic alternate to Linessa) Generic

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Table of contents:

Linessa is a prescription medication used for the prevention of pregnancy. It contains two female sex hormones, an estrogen (ethinyl estradiol) and a progestin (desogestrel) and works by preventing ovulation (the release of an egg from an ovary) and by changing the cervical mucus and the lining of the uterus to prevent the fertilization of an egg or implantation of a fertilized egg.

Note that Linessa does not protect against sexually transmitted infections and should be used in combination with condoms or other forms of protection.

Use and Dosage

Linessa comes in the form of 21- and 28-days tablet to take orally once a day at the same time each day. In case of 21-day pack: Take one tablet daily for 21 days, then do not take any tablets for 7 days, and then begin the next pack. For 28-day pack: Take one tablet daily for 21 days, then take one "reminder" tablet daily for 7 days, and then begin the next pack.

Talk with your doctor about the best time to start your tablets. The first day of your menstrual period (bleeding) is known as "Day 1." Your doctor may have you start your tablets on the first Sunday after your period starts or on Day 1 of your period. The tablets should be taken approximately the same time every day.

The Linessa tablet should be taken in the order specified on the package and should not be skipped or missed. If you miss a dose, you should take the missed dose as soon as possible, and continue with your regular schedule. Talk to your doctor about any other medications you are taking, as they may interact with Linessa.

Side Effects

Common Side Effects of Linessa (Desogestrel/Ethinyl Estradiol):

  • Abdominal cramping or bloating
  • Acne (usually less common after 3 months of treatment, and may improve if acne already exists)
  • Back pain
  • Breast pain, tenderness, or swelling
  • Diarrhea
  • Dizziness
  • General feeling of being unwell
  • Headaches
  • Heartburn
  • Nausea
  • Painful menstrual cramps
  • Unusual tiredness or weakness
  • Vomiting
  • Weight gain or loss

Serious Side Effects of Linessa (Desogestrel/Ethinyl Estradiol):

  • Breakthrough bleeding or spotting between periods
  • Breast lumps
  • Changes in sleep
  • Changes in the uterine bleeding pattern during or between menstrual periods, such as:
  • Changes in weight
  • Complete stop of menstrual bleeding for several months in a row, or stop of menstrual bleeding that only occurs sometimes
  • Dark urine
  • Decreased bleeding during periods
  • Decreased interest in activities
  • Depression
  • Diarrhea
  • Excessive eating
  • Frequent urination
  • Fruity breath odor
  • Increased blood pressure
  • Increased thirst
  • Infections
  • Loss of appetite
  • Low back or flank pain
  • Nausea
  • Pain
  • Pain when urinating
  • Pale stools
  • Poor concentration
  • Poor wound healing
  • Prolonged bleeding during periods
  • Swelling
  • Tenderness in upper abdominal area
  • Thoughts of suicide
  • Unexplained weight loss
  • Unusual swelling of the extremities
  • Vaginal infection with vaginal itching or irritation, or thick, white, or curd-like discharge
  • Vomiting
  • Weight loss
  • Yellowing of the skin or whites of the eyes

Forms and Strength

Linessa (Desogestrel/Ethinyl Estradiol) is available in the following forms and strength:

Linessa: Tablet

  • 21 days
  • 28 days


  • Smoking: Smoking while taking Linessa increases the risk of serious cardiovascular side effects such as blood clots, heart attacks, and strokes.
  • Medical history: Women with a history of blood clots, liver disease, certain cancers, or high blood pressure should use caution when taking Linessa.
  • Allergies: Women who are allergic to any of the active or inactive ingredients in Linessa should not take this medication.
  • Age: Linessa should not be used by women who have not yet started menstruating or who have reached menopause.
  • Interactions: Linessa may interact with other medications, such as antibiotics or anticonvulsants, and may reduce their effectiveness or increase the risk of side effects.
  • Weight: Women who are overweight or obese may be at a higher risk of developing serious cardiovascular side effects while taking Linessa.
  • Other conditions: Linessa may not be suitable for women with certain medical conditions such as diabetes, migraines, or depression.
  • Blood sugar levels: Linessa can affect blood sugar levels, so women with diabetes should monitor their blood sugar more closely when taking this medication.
  • Breastfeeding: Linessa should not be taken while breastfeeding, as small amounts of the hormones in the medication can be passed through breast milk and affect the baby.

Frequently Asked Questions (FAQ)

Will Linessa protect me from sexually transmitted infections (STIs)?

No, Linessa does not protect against STIs. Use additional barrier methods, such as condoms, to prevent the spread of STIs.

How long does it take for Linessa to be effective?

Linessa should be taken for at least 7 consecutive days before relying on it for contraception.

Can Linessa be used to treat menstrual problems or symptoms such as cramps or heavy bleeding?

Yes, Linessa may be prescribed for the treatment of menstrual problems or symptoms but be sure to discuss any concerns with your healthcare provider.

Can I take Linessa if I have irregular periods?

Yes, Linessa is sometimes prescribed to women with irregular periods to regulate their menstrual cycle and reduce symptoms.

Is it safe to take Linessa if I have a history of depression or mood disorders?

Discuss any history of depression or mood disorders with your healthcare provider before taking Linessa, as it may worsen these conditions in some patients.


It's important to purchase Linessa from verified Canadian pharmacy.

Additional information

Generic name:

Desogestrel/Ethinyl Estradiol




21 day, 28 day

Quantities Available:

63, 84


Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Linessa (Desogestrel/Ethinyl Estradiol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Linessa (Desogestrel/Ethinyl Estradiol).