Indications
Edronax (generically known as Roboxetine) is a selective norepinephrine reuptake inhibitor that has been used in the treatment of depression. It is indicated for the acute treatment of depressive illness/major depression and for maintaining the clinical improvement in patients initially responded to reboxetine.
Edronax (Reboxetine mesilate) works by increasing the levels of noradrenaline in the brain, which is thought to play a role in regulating mood. Specifically, Edronax blocks the reuptake of noradrenaline by nerve cells in the brain, which leads to an increase in the amount of noradrenaline available in the brain. This increase in noradrenaline may help to improve symptoms of depression in some patients.
Use and Dosage
Edronax is prescribed as a 4mg tablet to be taken orally before or after food. It may take a week or two after starting the tablets before you start feeling the effects. Swallow the tablets whole with a glass of water. Edronax tablets can be broken in half along the break line if your doctor has prescribed a half tablet.
The recommended therapeutic dose of Edronax is 4 mg to be taken twice daily (i.e., a total of 8 mg per day) administered orally. However, the dosages may vary based on individual factors such as age, tolerability, and medical history, follow the dosage instructions provided by your healthcare provider and on the medication packaging.
Take Edronax tablet at about the same time each day, once in the morning and once at night. Taking the tablet at the same time each day will have the best effect. It will also help you remember when to take it.
If a dose of Edronax is missed, patients should take it as soon as possible. If it is close to the time for the next dose, patients should skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for a missed dose.
Side Effects
Common Side Effects of Edronax (Roboxetine):
- Insomnia
- Dizziness
- Dry mouth
- Constipation
- Nausea
- Sweating
- Headache
- Lack or loss of appetite
- Agitation, anxiety
- Paraesthesia (pins and needles), inability to sit or stand still, altered taste sensation
- Lack of visual focus
- Increased heart rate, palpitations (heart pounding)
- Widened blood vessels, fall in blood pressure when standing up, increased blood pressure
- Vomiting
- Rash
- Sensation of incomplete emptying or slowed emptying of the bladder, urinary infection, painful urination, inability to completely empty the bladder
- Erectile dysfunction (impotence), ejaculatory pain, or ejaculatory delay
- Chills
Serious Side Effects of Edronax (Roboxetine):
- Hyponatremia (extremely low levels of sodium in the blood)
- Aggressive behavior
- Hallucinations
- Suicidal ideation
- Cold extremities
- Allergic skin inflammation
- Testicular pain
- Irritability
- Increased pressure in the eye
Forms and Strength
Edronax (Roboxetine) is available in the following forms and strength:
Edronax: Tablet
- 4mg
Cautions
- Edronax should be used with caution in patients with decreased kidney or liver function.
- Edronax should be used with caution in patients with a history of seizures or epilepsy.
- Edronax should be used with caution in patients with a history of heart disease or high blood pressure.
- Edronax should not be used in combination with other medications that affect serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs) or monoamine oxidase inhibitors (MAOIs).
- Edronax should be used with caution in patients with a history of urinary retention or prostate problems.
- Edronax should not be used in patients with a history of mania or hypomania.
- Edronax should be used with caution in patients with a history of bleeding disorders or taking medications that can cause bleeding.
- Edronax should not be used in patients who are allergic to reboxetine or have had an allergic reaction to it.
Frequently Asked Questions (FAQ)
Is Edronax addictive?
Edronax is not considered addictive and does not have the same potential for abuse as some other antidepressant medications.
Can Edronax cause weight gain?
Weight gain is not a common side effect of Edronax, but individual responses to medications can vary. Patients should speak with their doctor if they experience any unexpected changes in weight.
Can Edronax cause suicidal thoughts?
Like with other antidepressant medications, there is a small risk of increased suicidal thoughts or behavior when starting treatment with Edronax.
Can Edronax be used long-term?
There has been limited research on the long-term safety and efficacy of Edronax. Patients should discuss with their doctor about the appropriate duration of treatment for their individual needs.
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