Depo Medrol Injection (Methylprednisolone acetate)

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Depo Medrol Injection Brand
Dosage Quantity & Price
Methylprednisolone acetate (Generic alternate to Depo Medrol Injection) Generic

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Table of contents:

Depo-Medrol is a medication that contains methylprednisolone acetate, which is a corticosteroid that can be used to treat many different inflammatory conditions such as arthritis, lupus, psoriasis, and ulcerative colitis, among others.

Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. It can be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions.

Uses and Dosage

Depo-Medrol Vial should be used as directed by your doctor or healthcare provider. It is usually injected into a joint or muscle. To prepare the medication at home, learn all the preparation and usage instructions from your healthcare professional. Shake the Depo-Medrol Vial well before using it. Make sure the medication appears milky white before using it. Before using the medication, check it visually for any particles or discoloration. If you see any unusual appearances, do not use the medication and consult with your healthcare provider.

The dosage of Depo-Medrol Vial is based on your medical condition and response to treatment. Do not increase your dose or use this medication more often than prescribed without consulting your doctor. Your condition will not improve any faster, and the risk of side effects will increase.

Do not stop using Depo-Medrol Vial without consulting your doctor, as some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

Side effect

Common Side Effects of Depo Medrol Injection (Methylprednisolone Acetate):

  • Acne
  • Appetite changes
  • Dizziness
  • Headache
  • Heartburn
  • Increased sweating
  • Injection site reactions (pain, redness, swelling)
  • Nausea
  • Trouble sleeping
  • Vomiting

Serious Side Effects of Depo Medrol Injection (Methylprednisolone Acetate):

  • Allergic reactions, including anaphylaxis, which can be life-threatening
  • Increased risk of infections, including serious fungal infections and sepsis
  • Pancreatitis or other gastrointestinal disorders
  • Fluid retention, which can lead to congestive heart failure
  • Vision problems, including glaucoma or cataracts
  • Mood changes or psychiatric disorders, including depression or anxiety
  • Endocrine disorders, including Cushing's syndrome or adrenal suppression
  • Other serious adverse events may occur, such as osteonecrosis, myopathy, or hypersensitivity reactions

Form and Strength

Depo Medrol Injection (Methylprednisolone Acetate) is available in the following forms and strength:

Depo Medrol Injection: Vial

  • 20mg/mL
  • 40mg/mL
  • 80mg/mL


  • It should not be used in patients who have experienced previous hypersensitivity to Methylprednisolone Acetate or other corticosteroids.
  • Long-term use or high doses may increase the risk of developing osteoporosis or other bone-related complications.
  • Patients with a history of diabetes or a family history of diabetes should be monitored closely as Depo-Medrol may increase blood sugar levels.
  • Depo-Medrol injection may increase the risk of infection and should be used with caution in patients with a history of recent or chronic infections, or those undergoing treatment for an active infection.
  • Depo-Medrol may cause mood changes, such as depression or anxiety, and should be used with caution in patients with a history of psychiatric disorders.
  • Depo-Medrol injection may mask or exacerbate symptoms of infections, such as fever or inflammation. Patients should therefore be monitored closely for signs of infection during and after treatment with Depo-Medrol injection.
  • Depo-Medrol injection may interact with other medications, including certain vaccines, and should be used with caution in patients taking other medications or with a history of vaccine allergies.
  • Patients with a history of gastrointestinal disorders or ulcers may be at an increased risk of developing gastrointestinal bleeding or perforation with use of Depo-Medrol injection.
  • Depo-Medrol injection may cause eye problems such as glaucoma or cataracts, especially with prolonged use or high doses.
  • Depo-Medrol injection may suppress the immune system and increase the risk of infections or malignancies, especially with long-term use or high doses.

Frequently Asked Questions (FAQ)

What is Depo-Medrol?

Depo-Medrol is a medication that contains methylprednisolone acetate, a corticosteroid that can be used to treat various inflammatory conditions.

How is Depo-Medrol administered?

Depo-Medrol can be injected via several routes including intramuscular, intra-articular, periarticular, intrabursal, and intralesional, depending on the specific condition being treated and the severity of symptoms.

When is Depo-Medrol injection given?

Depo-Medrol injection is usually given when other anti-inflammatory medications have not been effective or when a more rapid response is needed.

Is it safe to use Depo-Medrol during pregnancy?

The safety of Depo-Medrol during pregnancy has not been established, and it should only be used during pregnancy if the benefits outweigh the risks.


It's important to purchase Depo Medrol Injection from verified Canadian pharmacy.

Additional information

Generic name:

Methylprednisolone acetate




20mg/mL, 40mg/mL, 80mg/mL

Quantities Available:

2mL, 5mL


Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Depo Medrol Injection (Methylprednisolone acetate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Depo Medrol Injection (Methylprednisolone acetate).