Indications
Coly-Mycin M is an antibiotic medication used to treat infections caused by certain gram-negative bacteria. It contains the active ingredient colistimethate sodium. Colistimethate works by binding to bacterial cell walls and disrupting their function. This ultimately leads to cell death, effectively treating bacterial infections caused by specific bacteria.
Colistimethate is intended for parenteral use, meaning it is administered through injection or infusion into a vein or muscle. It is used to reduce the development of drug-resistant bacteria and maintain the effectiveness of antibacterial drugs. Note that Coly-Mycin M should only be used for bacterial infections that it has been specifically prescribed for.
Use and Dosage
Colistimethate injection is available as a powder that needs to be mixed with a liquid and injected into a vein over 3 to 5 minutes, or into the muscles of the bottom or thigh. The usual dosage is every 6 to 12 hours. Alternatively, a continuous intravenous infusion over 22 to 23 hours may also be given, depending on the type of infection and the patient’s health.
The duration of the treatment varies from person to person and depends on their general health and how well they respond to the medication. If you are administering the medication at home, make sure you understand the instructions your healthcare provider explains to you. You can expect to feel better within the first few days of treatment but keep taking the medication until the prescribed dosage is complete. Even if you feel better, stopping early or missing doses can lead to incomplete treatment and antibiotic resistance in bacteria.
Side Effects
Common Side Effects of Coly-Mycin M (Colistimethate):
- Dizziness
- Spinning sensation
- Itching or mild rash
- Mild skin rash
- Numbness or tingling in your hands, feet, mouth, or tongue
- Slurred speech
- Spinning feeling
- Upset stomach
Serious Side Effects of Coly-Mycin M (Colistimethate):
- Diarrhea that is watery or bloody
- Feeling tired or short of breath
- Fever
- Little or no urination
- Painful or difficult urination
- Seizure (convulsions)
- Severe stomach pain
- Slow breathing
- Swelling in your feet or ankles
- Unusual muscle weakness
Forms and Strength
Coly-Mycin M (Colistimethate) is available in the following forms and strength:
Coly-Mycin M: injections
- 150 mg
Colistimethate: injections
- 150 mg
Cautions
- Impaired renal function: Coly-Mycin M should be used with caution in individuals with impaired renal function.
- Drug interactions: Coly-Mycin M may interact with other drugs, inform healthcare professionals of all medications being taken before starting treatment with Coly-Mycin M.
- Side effects: Coly-Mycin M may cause side effects, including but not limited to kidney toxicity, hearing loss, and breathing difficulties. Follow the dosage and administration instructions provided by a healthcare professional and report any side effects or concerns promptly.
- Sensitivity to colistin: Individuals who are sensitive to colistin or other polymyxin antibiotics should use Coly-Mycin M with caution.
- Prolonged use: Prolonged or frequent use of Coly-Mycin M may increase the risk for developing drug-resistant bacteria.
- Use during pregnancy and lactation: Coly-Mycin M should be used with caution in pregnant or breastfeeding women, as there is limited information on the safety of the medication in these populations.
Frequently Asked Questions (FAQ)
What should I do if I miss a dose of Coly-Mycin M?
If you miss a dose of Coly-Mycin M, you should contact your healthcare provider for further instructions. Do not try to make up for a missed dose by taking extra medication.
How long does it take for Coly-Mycin M to start working?
The time it takes for Coly-Mycin M to start working can vary depending on the severity of the infection and the individual patient.
Can Coly-Mycin M be used to treat all types of bacterial infections?
No, Coly-Mycin M is only effective against certain types of bacteria and should only be used for bacterial infections that it has been specifically prescribed for.
How should Coly-Mycin M be stored?
Coly-Mycin M should be stored at room temperature away from light and moisture. It should not be frozen or refrigerated.
Can Coly-Mycin M be used in children?
Yes, Coly-Mycin M can be used in pediatric patients, but the dose may need to be adjusted based on weight and other factors.
Resources
- https://medlineplus.gov/druginfo/meds/a682860.html
- https://www.webmd.com/drugs/2/drug-9089/coly-mycin-m-injection/details
- https://www.drugs.com/mtm/coly-mycin-m.html
- https://www.goodrx.com/colistimethate/what-is
- https://www.rxlist.com/coly-mycin-drug.htm
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050108s026lbl.pdf
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