Indications
Atopica is a medication commonly used to treat atopic dermatitis, also known as skin allergies, in both dogs and cats. It contains cyclosporine, a non-steroidal immune modulating agent that helps to control the immune response that leads to skin inflammation and itching.
Atopica is available in capsule form for both dogs and cats and it is designed to immediately form a microemulsion in an aqueous environment upon ingestion. It should only be used under the supervision of a veterinarian. In addition to atopic dermatitis, Atopica has also been used to treat other dermatological conditions, such as inflammatory bowel disease, which cause itching and skin lesions.
Uses and Dosage
Cyclosporine (Atopica) capsules should be given according to your veterinarian’s instructions. Do not change the way you give Cyclosporine without speaking with your veterinarian first. The capsules should be given on an empty stomach, so please wait at least one hour before or two hours after a meal before giving Cyclosporine.
The recommended dosages of Atopica (cyclosporine) may vary depending on the animal's weight and condition being treated. Here are some examples of recommended dosages from the search results:
- For cats with atopic dermatitis, the initial dose is 3.2 mg/lb./day (7 mg/kg/day) as a single daily dose for a minimum of 4 to 6 weeks or until resolution of clinical signs.
- For dogs with atopic dermatitis, the initial target daily dose of Atopica is 5 mg/kg/day (range of 3.3 - 6.7 mg/kg/day) given as a single daily dose for 30 days.
- There are also specific dosage instructions provided for dogs based on their weight: for dogs 64.1-79 lbs., give a combination of one 100 mg capsule and one 50 mg capsule as a single dose. For dogs 79.1-121 lbs. give two 100 mg capsules as a single dose.
Side Effect
Common Side Effects of Atopica (Cyclosporine):
- Decreased appetite
- Diarrhea
- Vomiting
Serious Side Effects of Atopica (Cyclosporine):
- Persistent Otitis Externa (swimmer’s ear)
- Urinary Tract Infection
- Anorexia
- Lethargy
- Gingival Hyperplasia (overgrowth of gums)
- Lymphadenopathy (swelling of lymph nodes)
Form and Strength
Atopica (Cyclosporine) is available in the following forms and strength:
Atopica: Capsule
- 25 mg
Caution
- Atopica should be used with caution with drugs that affect the P-450 enzyme system.
- Cyclosporine lowers the ability to fight infections, increasing the risk of serious infections.
- Caution should be exercised when using cyclosporine in dogs with a history of neoplasia (tumor formation).
- Atopica is not recommended for animals with a history of hypersensitivity to cyclosporine.
- Atopica should be used with caution in dogs with impaired renal function.
- Extreme caution is recommended when using a combination of cyclosporine and ketoconazole.
Frequently Asked Questions (FAQ)
Can Atopica be given with food?
No, Atopica should be given on an empty stomach, either one hour before or two hours after a meal.
Can Atopica be used in pregnant or nursing animals?
The safety of Atopica use in pregnant or nursing animals has not been established. Consult with a veterinarian before using Atopica in pregnant or nursing animals.
Is Atopica safe for all animals?
Atopica may not be safe for animals with certain medical conditions or on certain medications, and it is not recommended for use in pregnant or nursing animals. Consult with a veterinarian before using Atopica in your pet.
Can Atopica be used long-term?
Atopica may be used long-term to manage chronic skin allergies in animals, but it should be used under the supervision of a veterinarian and dosage adjustments may be necessary.
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