Apoquel (Oclacitinib)

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Apoquel Brand
Dosage Quantity & Price
Oclacitinib (Generic alternate to Apoquel) Generic

We don't sell this generic-version medication.

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Table of contents:

Apoquel (Oclacitinib) is an oral medication used to effectively manage itching associated with allergic dermatitis in dogs aged 12 months or older. Apoquel is used to control the itching and inflammation caused by allergic skin diseases such as allergic dermatitis and atopic dermatitis. It works by targeting the Janus kinase (JAK) pathway, which is responsible for the itching and inflammation in allergic skin diseases.

Apoquel is a potent anti-allergic medication typically prescribed by veterinarians to provide relief from acute and chronic canine pruritus. It can be used to treat other skin conditions in dogs, such as seborrhea, contact dermatitis, and other forms of allergic dermatitis. It is used occasionally in cats to treat certain skin conditions, such as allergic dermatitis and eosinophilic granuloma complex.

Oclacitinib is a fast-acting and safe treatment that can provide relief from itching within 4 hours and has been shown to effectively control the symptoms of pruritus within 24 hours. Apoquel is an excellent option for those seeking a rapid and safe way to alleviate their pet's discomfort.

Uses and Dosage

Oclacitinib is available in the form of a tablet and is given by mouth. This medication can be taken with or without food. If your pet experiences stomach upset when taken on an empty stomach, it is recommended to give future doses with food. You should ensure that you wash your hands immediately after administering the medication.

The dose of Apoquel is 0.4-0.6 mg/kg every 12 hours for up to 14 days, then 0.4-0.6 mg/kg once daily thereafter. Stay within the recommended dose range, as going above the recommended dose could lead to immune suppression, and going below the range may not be effective in controlling the condition.

Side Effects

Common Side Effects of Apoquel Include:

  • Anorexia
  • Decreased energy (lethargy)
  • Diarrhea
  • Increased thirst
  • Vomiting

Serious Side Effects Oclacitinib Include:

  • Aggression
  • Cancer (new tumors or worsening of existing ones)
  • Demodicosis (a skin disease caused by Demodex mites)
  • Low white blood cell count
  • Serious infections (including pneumonia, urinary tract infections, and skin infections)
  • Skin masses, including cysts between the toes and skin cancer

Form and Strength

Apoquel is available in the following forms and strengths:

Apoquel: Tablet

  • 3.6 mg
  • 5.4 mg
  • 16 mg


  • Note that Apoquel should only be used under the guidance of a veterinarian and should not be used in pregnant or nursing animals.
  • If your dog is showing signs of infection or pneumonia, such as trouble breathing, lethargy, or a fever, stop giving Apoquel and seek veterinary care immediately.
  • Apoquel should not be given to puppies under one year of age, as it has not been studied in this age group.
  • If you see abnormal skin changes or growths, severe side effects, or suspect an overdose of Apoquel, ask veterinary care immediately. Apoquel is not intended to treat infection or skin changes and could make the condition worse.

Frequently Asked Questions (FAQ)

What if I miss giving my pet the medication?

If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give it at the next scheduled time and return to the regular dosing schedule. Never give your pet two doses at once or give extra doses.

How long can a dog take Apoquel?

Some dogs have been treated with Apoquel for more than five years without any problem, and we do not expect there will be long-term problems.

Do allergies shorten a dog's life?

While not usually life threatening, allergies in dogs do cause discomfort. Most symptoms are associated with dermatologic problems, but some can also lead to chronic respiratory issues in some dogs if untreated for long periods of time.

How long can a dog take Apoquel?

Apoquel can be given short-term or long-term. Your veterinarian will recommend an appropriate treatment length for your dog.


It's important to purchase Apoquel from verified Canadian pharmacy.

Additional information

Generic name:





3.6mg, 5.4mg, 16mg

Quantities Available:

60, 100