Exjade (Deferasirox)

Prescription Required

Formulation: Dispersible Tablet

Exjade

(Brand Option)

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Prescription Required

Formulation: Dispersible Tablet

Deferasirox

(Generic Alternative)

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Exjade (active ingredient: deferasirox) is a prescription medication indicated for the following:

Chronic Iron Overload: Exjade is used for the treatment of chronic iron overload due to blood transfusions in patients 2 years of age and older.
Non-Transfusion-Dependent Thalassemia: It is also indicated for the treatment of chronic iron overload in patients 10 years of age and older with non-transfusion-dependent thalassemia syndromes.

Exjade belongs to a class of drugs known as iron chelators, which work by binding to excess iron in the body and facilitating its excretion, thereby reducing iron levels in the blood and tissues.

Exjade is available in tablet and suspension form and should be taken once daily on an empty stomach, preferably 30 minutes before food. The tablet should not be chewed, or it must be swallowed whole. The tablets should be used in water, orange juice, or apple juice until the tablets have completely broken apart and are well mixed into the liquid. Patients should drink all the mixture right away, using about 1/2 cup (3.5 ounces/100 milliliters) of liquid for doses of less than 1 gram and about 1 cup (7 ounces/200 milliliters) for doses more than 1 gram.

Patients should take Exjade by mouth on an empty stomach at least 30 minutes before food, as directed by their healthcare provider, usually once daily. Patients should avoid taking this medication with antacids that contain aluminum, as this may affect how deferasirox works. Patients should always follow their healthcare provider’s instructions when taking this medication.

Common Side Effects of Exjade (Deferasirox):

Abdominal discomfort
Diarrhea
Dizziness
Fatigue
Headache
Insomnia
Loss of appetite
Nausea
Vomiting

Serious Side Effects of Exjade (Deferasirox):

Bleeding
Easy bruising
Fever, chills, or persistent sore throat (signs of infection)
Hearing loss
Symptoms of kidney problems (change in urine output, frothy urine)
Symptoms of liver damage (abdominal pain, persistent vomiting, yellowish skin, dark urine)
Vision changes

Exjade (Deferasirox) available in the following forms and strength:

Exjade: Dispersible Tablet

125 mg
250 mg
500 mg

Deferasirox: Dispersible Tablet

125 mg
500 mg

Exjade can cause renal failure, particularly in patients with pre-existing renal impairment or those who are taking nephrotoxic drugs. Close monitoring of renal function is necessary.
Exjade can cause nausea, vomiting, and diarrhea. In some cases, these side effects can be severe and require dose reduction or discontinuation of therapy.
Exjade can cause abnormal liver function tests, hepatitis, and jaundice. These effects are generally reversible upon discontinuation of therapy.
Exjade can cause skin rashes, which may require treatment with antihistamines or corticosteroids.
Exjade can cause auditory and ocular disturbances, including high-frequency hearing loss, decreased visual acuity, and cataracts. Regular monitoring of these functions is necessary.
Exjade can lower the body’s immune response and increase the risk of infections. Patients taking the drug should avoid close contact with people with communicable infections.
Exjade may interact with other drugs, including antacids, antifungals, and antibiotics, leading to adverse effects.
Exjade can cause bleeding, such as bruising and petechiae. Patients who develop these side effects should be monitored closely and assessed for potential bleeding disorders.
Exjade can cause allergic reactions, including rash, pruritus, urticaria, and anaphylaxis. These effects require immediate medical attention.
Exjade is not recommended for use during pregnancy or breastfeeding due to the potential risk to the fetus or infant.

Can Exjade cause kidney damage?

Yes, Exjade can cause kidney damage, particularly in patients with pre-existing renal impairment or those taking nephrotoxic drugs. Close monitoring of renal function is necessary.

What should I do if I overdose on Exjade?

If you overdose on Exjade, seek immediate medical attention. Symptoms of overdose may include gastrointestinal side effects, renal failure, and liver function abnormalities.

How long does it take for Exjade to work?

The effectiveness of Exjade varies depending on factors such as the patient’s iron overload level, age, and disease type. It may take several months to see significant reductions in iron levels.

Can Exjade be taken with food?

Yes, Exjade can be taken with or without food. However, it should be taken at the same time each day to maintain consistent blood levels.

Can Exjade be used in children?

Yes, Exjade is approved for use in children aged 2 years and above who have received frequent blood transfusions due to conditions such as thalassemia and sickle cell disease.

REVIEWS

Additional Information Book

Generic name:	Deferasirox
Formulation:	Dispersible Tablet
Strength(s):	125mg, 250mg, 500mg
Quantities Available:	28, 84

How to Order

How much Exjade can I order at once from a Canadian pharmacy?

When ordering Exjade (deferasirox) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time. This quantity is standard for prescription medications to ensure continuous treatment without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Exjade is available in 500 mg strength. The dosage and quantity you can order will depend on your specific prescription, which is based on your body weight and the healthcare provider’s instructions.

For example, if you are prescribed Exjade 500 mg daily and take it once daily, for a 90-day supply, you would order approximately 90 tablets (90 days x 1 tablet per day).

Do you sell deferasirox?

Yes, we sell deferasirox on our website. You can enjoy low prices on this medication. To purchase deferasirox, you will need a valid prescription from your healthcare provider. We require this to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account.

Do you offer shipping of Exjade (deferasirox) to the United States?

Yes, we ship Exjade (deferasirox) to both the United States and Puerto Rico.

Exjade (Deferasirox)

Exjade

Deferasirox

Common Side Effects of Exjade (Deferasirox):