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Galliprant (Grapiprant) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Galliprant

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Prescription Prescription Required FormationFormulation: Tablet

Grapiprant

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Galliprant (active ingredient: grapiprant) is a prescription medication used in dogs to help control the pain and inflammation caused by osteoarthritis.

Osteoarthritis is a common, long-term joint disease that causes the cartilage within the joints to wear down over time. This can lead to pain, stiffness, inflammation, and reduced mobility, making it difficult for dogs to perform everyday activities.

Dogs with osteoarthritis may show signs such as:

  • Limping or lameness.
  • Stiffness, especially after resting.
  • Difficulty standing up, climbing stairs, or jumping.
  • Reluctance to exercise or play.
  • Decreased activity levels.
  • Signs of pain when walking or moving.

Galliprant helps relieve these symptoms, allowing many dogs to move more comfortably and enjoy a better quality of life.

How Does Galliprant Work?

Galliprant belongs to a group of medications called piprant antagonists.

Unlike many traditional nonsteroidal anti-inflammatory drugs (NSAIDs), Galliprant works by specifically blocking the prostaglandin E2 (PGE2) EP4 receptor, which is primarily responsible for the pain and inflammation associated with osteoarthritis.

By targeting this specific receptor, Galliprant helps:

  • Reduce joint pain.
  • Decrease inflammation.
  • Improve mobility and comfort.
  • Help dogs remain more active.

Because Galliprant selectively blocks the EP4 receptor rather than broadly blocking prostaglandins throughout the body, it is designed to provide pain relief while minimizing effects on other prostaglandins that help protect the stomach, kidneys, and other organs.

Galliprant does not cure osteoarthritis or reverse joint damage. However, when used as directed by a veterinarian, it can help manage pain and improve your dog’s comfort and quality of life.

Galliprant is a prescription medication used in dogs to help control the pain and inflammation associated with osteoarthritis (OA). It is approved for use in dogs 9 months of age and older that weigh at least 8 pounds (3.6 kg).

Osteoarthritis is a chronic joint disease that causes the cartilage within the joints to break down over time. This can lead to pain, stiffness, inflammation, and reduced mobility.

Dogs with osteoarthritis may show signs such as:

  • Limping or lameness.
  • Stiffness after resting.
  • Difficulty standing, climbing stairs, or jumping.
  • Decreased activity or reluctance to exercise.
  • Signs of pain during movement.

Galliprant helps relieve these symptoms, allowing many dogs to move more comfortably and maintain a better quality of life.

How to Give Galliprant

Galliprant tablets should be given by mouth once daily, exactly as prescribed by your veterinarian. The tablets may be given with or without food, although some dogs tolerate the medication better when it is given with a small amount of food if stomach upset occurs.

Your veterinarian will determine the appropriate dose based on your dog’s body weight. Do not adjust the dose or stop treatment without consulting your veterinarian.

Recommended Dosage

The recommended dose of Galliprant is:

  • 2 mg/kg (0.9 mg/lb) by mouth once daily.

Galliprant is available as 20 mg, 60 mg, and 100 mg tablets.

Typical dosing based on body weight is:

 

Dog’s Weight Recommended Dose
8–15 lb (3.6–6.8 kg) ½ of a 20 mg tablet once daily
15.1–30 lb (6.9–13.6 kg) 1 × 20 mg tablet once daily
30.1–45 lb (13.7–20.4 kg) ½ of a 60 mg tablet once daily
45.1–75 lb (20.5–34 kg) 1 × 60 mg tablet once daily
75.1–150 lb (34.1–68 kg) 1 × 100 mg tablet once daily
Over 150 lb (68 kg) Your veterinarian may prescribe a combination of tablets to achieve the correct dose.

 

Important Tips

  • Give Galliprant once daily at about the same time each day.
  • Dogs weighing less than 8 pounds (3.6 kg) cannot be accurately dosed with the available tablet strengths.
  • If you miss a dose, give it when you remember unless it is almost time for the next dose. Do not give two doses at the same time.
  • Use the lowest effective dose for the shortest duration needed to control your dog’s pain, as recommended by your veterinarian.

Common Side Effects of Galliprant (grapiprant):

  • Vomiting.
  • Soft stools or diarrhea.
  • Decreased appetite.
  • Tiredness or decreased activity (lethargy).
  • Increased thirst.
  • Increased urination.
  • Weight loss.
  • Constipation.
  • Excessive gas (flatulence).
  • Changes in behavior or activity level.

Serious Side Effects of Galliprant (grapiprant):

  • Blood in the vomit or stool, or black, tarry stools.
  • Severe or persistent vomiting or diarrhea.
  • Significant loss of appetite lasting more than a day.
  • Extreme weakness or collapse.
  • Yellowing of the eyes or gums (jaundice), which may indicate liver problems.
  • Increased drinking or urination accompanied by lethargy, which may suggest kidney problems.
  • Pale gums or unusual bruising or bleeding.

Galliprant (grapiprant) is available in the following forms and strength:

Galliprant: Tablet

  • 60 mg

Before giving Galliprant to your dog, tell your veterinarian about your dog’s complete medical history, including any existing health conditions and all medications or supplements they are taking. This helps ensure the medication is safe and appropriate for your pet.

Use Only as Directed

Galliprant should be used only in dogs. It is approved for dogs 9 months of age and older that weigh at least 8 pounds (3.6 kg).

Do not give Galliprant to cats or other animals unless specifically directed by a veterinarian.

Tell Your Veterinarian About Your Dog’s Medical History

Before starting Galliprant, tell your veterinarian if your dog:

  • Has kidney disease.
  • Has liver disease.
  • Has stomach or intestinal ulcers.
  • Has a history of vomiting or diarrhea.
  • Has bleeding disorders.
  • Is dehydrated.
  • Has heart disease.
  • Is pregnant, intended for breeding, or nursing puppies.

Dogs with these conditions may require closer monitoring or a different treatment.

Gastrointestinal Effects

Galliprant may cause stomach or intestinal irritation. Watch your dog for signs such as:

  • Vomiting.
  • Diarrhea.
  • Loss of appetite.
  • Black, tarry stools.
  • Blood in the vomit or stool.

Stop the medication and contact your veterinarian immediately if any of these symptoms occur.

Kidney and Liver Function

Although Galliprant is designed to be more selective than traditional NSAIDs, it may still affect kidney or liver function, particularly in dogs with existing disease or those that are dehydrated.

Your veterinarian may recommend periodic blood tests to monitor your dog’s kidney and liver health during long-term treatment.

Drug Interactions

Tell your veterinarian about all medications, vitamins, supplements, and herbal products your dog is receiving.

Galliprant should be used with caution when given with:

  • Other nonsteroidal anti-inflammatory drugs (NSAIDs).
  • Corticosteroids, such as prednisone or dexamethasone.
  • Medications that may affect the kidneys or increase the risk of stomach ulcers.

Using these medications together may increase the risk of serious side effects.

Pregnancy and Breeding

The safety of Galliprant has not been established in dogs that are:

  • Pregnant.
  • Nursing puppies.
  • Intended for breeding.

Your veterinarian will determine whether Galliprant is appropriate if your dog falls into one of these groups.

Allergic Reactions

Do not give Galliprant to your dog if they have a known allergy to grapiprant or any of the ingredients in the medication.

Seek emergency veterinary care immediately if your dog develops signs of an allergic reaction, including:

  • Swelling of the face or muzzle.
  • Hives or severe itching.
  • Difficulty breathing.
  • Collapse.

Monitoring During Treatment

While your dog is taking Galliprant, monitor them for any changes in appetite, energy level, bowel movements, or behavior. Contact your veterinarian if your dog develops:

  • Persistent vomiting or diarrhea.
  • Loss of appetite.
  • Unusual tiredness or weakness.
  • Increased thirst or urination.
  • Yellowing of the eyes or gums.
  • Black stools or vomiting blood.

Regular veterinary checkups may be recommended, especially if your dog will be taking Galliprant for an extended period, to help ensure the medication remains safe and effective.

How long does Galliprant take to work?

Many dogs begin to experience pain relief within a few hours after taking Galliprant. However, it may take several days to a few weeks of daily treatment to achieve the full benefits, especially in dogs with chronic osteoarthritis. Continue giving the medication exactly as prescribed by your veterinarian.

How often should Galliprant be given?

Galliprant is typically given once daily by mouth. Your veterinarian will determine the correct dose based on your dog’s body weight. Give the medication at approximately the same time each day and follow your veterinarian’s instructions carefully.

Can Galliprant be given with food?

Yes. Galliprant may be given with or without food. If your dog develops mild stomach upset, giving the medication with a small meal or treat may help reduce nausea.

What should I do if I miss a dose?

If you miss a dose, give it as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and continue with your dog’s regular dosing schedule. Do not give two doses at the same time to make up for a missed dose.

Is Galliprant safe for long-term use?

Yes. Galliprant is commonly prescribed for the long-term management of osteoarthritis pain in dogs. Your veterinarian may recommend periodic checkups and blood tests to monitor your dog’s overall health, especially if the medication is used for an extended period.

Can Galliprant be used with other medications?

Galliprant can interact with certain medications. Tell your veterinarian about all prescription medications, over-the-counter products, supplements, and herbal products your dog is receiving before starting treatment. Galliprant should generally not be used at the same time as other NSAIDs (such as carprofen, meloxicam, or deracoxib) or corticosteroids (such as prednisone), unless specifically directed by your veterinarian.

What are the most common side effects of Galliprant?

The most common side effects include vomiting, diarrhea, soft stools, decreased appetite, and tiredness (lethargy). Contact your veterinarian if these side effects are severe, persistent, or if your dog develops signs of a more serious reaction, such as blood in the stool, persistent vomiting, or unusual weakness.

Can Galliprant cure osteoarthritis?

No. Galliprant does not cure osteoarthritis or repair damaged joints. It helps control pain and inflammation, allowing your dog to move more comfortably and maintain a better quality of life. Your veterinarian may also recommend weight management, regular exercise, joint supplements, or physical therapy as part of your dog’s overall treatment plan.

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Additional Information Book
Generic name:

Grapiprant

Formulation:

Tablet

Strength(s):

60mg

Quantities Available:

30

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Galliprant can I order at once from a Canadian pharmacy?

When ordering Galliprant (grapiprant) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard for many prescription medications to ensure continuous treatment without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Galliprant is available in a 60 mg dosage, taken once daily. For a 90-day supply, you would order 90 tablets (90 days x 1 tablet per day).

Do you sell grapiprant?

No, we don’t sell grapiprant. However, you can still enjoy low prices on Galliprant, which contains grapiprant as an active ingredient. To purchase Galliprant, you will need a valid prescription from your healthcare provider, as we require this to dispense the medication. You can conveniently provide your prescription by mailing, faxing, or uploading it through your online account during the ordering process.

Do you offer shipping of Galliprant (grapiprant) to the United States?

Yes, we ship Galliprant (grapiprant) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Galliprant (Grapiprant). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Galliprant (Grapiprant).