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Vetoryl (Trilostane) Shopper Approved

Prescription Prescription Required FormationFormulation: Capsule

Vetoryl

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Prescription Prescription Required FormationFormulation: Capsule

Trilostane

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Vetoryl contains the active ingredient trilostane. It is a prescription veterinary medication used to treat Cushing’s disease in dogs.

Cushing’s Disease in Dogs

Cushing’s disease happens when a dog’s body produces too much cortisol, a hormone made by the adrenal glands.

Vetoryl is used to treat dogs with:

  • Pituitary-dependent Cushing’s disease
  • Certain cases of adrenal-dependent Cushing’s disease

Common signs of Cushing’s disease may include increased thirst, frequent urination, increased appetite, panting, hair loss, a pot-bellied appearance, and reduced energy.

How Vetoryl Works

Vetoryl belongs to a group of medications called adrenal steroid synthesis inhibitors.

It works by blocking an enzyme called 3β-hydroxysteroid dehydrogenase.

This reduces the amount of cortisol produced by the adrenal glands and helps bring cortisol levels closer to a healthier range.

Important Note

Vetoryl helps control Cushing’s disease, but it does not cure the underlying condition.

Dogs taking Vetoryl need regular veterinary monitoring, including blood tests, to make sure cortisol levels do not become too low and that the dose remains appropriate.

Vetoryl comes as a capsule that is given by mouth.

Give Vetoryl with food, exactly as prescribed by your veterinarian.

Recommended Dose

The dose of Vetoryl depends on your dog’s:

  • Body weight
  • Symptoms
  • Cortisol levels
  • Response to treatment
  • Overall health

Your veterinarian will choose the appropriate starting dose and may adjust it over time based on blood test results and your dog’s symptoms.

Do not change the dose on your own.

Give Vetoryl at the Same Time Each Day

Try to give Vetoryl at about the same time every day.

If your dog is prescribed Vetoryl once daily, your veterinarian may recommend giving it in the morning with food so that follow-up hormone testing can be timed appropriately.

Monitor Your Dog Closely

Watch your dog carefully while they are taking Vetoryl.

Contact your veterinarian promptly if you notice:

  • Loss of appetite
  • Vomiting
  • Diarrhea
  • Unusual tiredness or weakness
  • Shaking
  • Collapse
  • Significant changes in drinking or urination

Loss of appetite, vomiting, low energy, diarrhea, and weakness are among the reported adverse effects of Vetoryl.

Regular Veterinary Monitoring Is Important

Dogs taking Vetoryl need regular veterinary checkups and blood tests.

Your veterinarian may monitor:

  • Cortisol response
  • Electrolytes
  • Kidney function
  • Liver function
  • Your dog’s symptoms and overall condition

Frequent monitoring is especially important during the first few months of treatment. Follow-up testing is then usually continued periodically based on your dog’s response.

Continue Vetoryl as Prescribed

Vetoryl helps control Cushing’s disease but does not cure it.

Continue giving it for as long as your veterinarian recommends.

Do not stop treatment or change the dose unless your veterinarian tells you to.

Common Side Effects of Vetoryl (Trilostane):

  • Diarrhea
  • Lethargy/dullness
  • Poor/reduced appetite
  • Vomiting
  • Weakness

Serious Side Effects of Vetoryl (Trilostane):

  • Collapse
  • Hemorrhagic diarrhea
  • Hypoadrenocortical crisis or adrenal necrosis/rupture (may result in death)
  • Severe depression

Vetoryl (Trilostane) is available in the following forms and strength:

Vetoryl: Capsule

  • 30 mg

Watch for Side Effects

Vetoryl can cause side effects in some dogs.

Contact your veterinarian if your dog develops:

  • Unusual tiredness or weakness
  • Loss of appetite
  • Vomiting
  • Diarrhea
  • Shaking
  • Collapse

These symptoms may mean that cortisol levels have become too low or that your dog is having another serious reaction.

The Dose May Need to Be Adjusted

The correct Vetoryl dose is different for each dog.

Your veterinarian may change the dose based on your dog’s symptoms, blood test results, and response to treatment.

Do not increase, decrease, or skip doses unless your veterinarian tells you to.

Kidney or Liver Problems

Tell your veterinarian if your dog has kidney or liver disease.

Vetoryl may not be appropriate for some dogs with these conditions, and closer monitoring may be needed.

Pregnancy and Nursing

Vetoryl should not be used in pregnant dogs.

Tell your veterinarian if your dog is pregnant, may become pregnant, or is nursing puppies before starting treatment.

Regular Blood Tests Are Important

Dogs taking Vetoryl need regular veterinary monitoring.

Your veterinarian may check:

  • Cortisol response
  • Electrolyte levels
  • Kidney function
  • Liver function
  • Your dog’s symptoms and overall health

These tests help make sure the medication is working safely and that the dose remains appropriate.

Risk of Cortisol Becoming Too Low

Vetoryl lowers cortisol production.

If cortisol levels become too low, your dog may develop hypoadrenocorticism, also called Addison’s disease.

Signs may include severe weakness, loss of appetite, vomiting, diarrhea, dehydration, shaking, or collapse.

Seek veterinary care promptly if these symptoms occur.

Drug Interactions

Tell your veterinarian about all medications, supplements, and other products your dog receives.

Extra caution may be needed with medications such as:

  • Potassium-sparing diuretics
  • ACE inhibitors
  • Certain anti-inflammatory medications

Some combinations may increase the risk of high potassium levels or other side effects.

Give the Correct Dose

Giving too much Vetoryl can reduce cortisol to dangerously low levels.

Giving too little may not adequately control Cushing’s disease.

Give each dose exactly as prescribed and do not change the amount on your own.

Long-Term Treatment

Many dogs with Cushing’s disease require long-term treatment.

Because your dog’s response can change over time, regular monitoring remains important throughout treatment.

Your veterinarian may adjust the dose as your dog’s condition changes.

Follow Your Veterinarian’s Instructions

Give Vetoryl exactly as directed and with food.

Do not stop treatment, restart it after a break, or change the dose without speaking with your veterinarian.

Contact your veterinarian if your dog’s symptoms worsen or new symptoms develop.

When is the best time to give my dog Vetoryl?

Vetoryl is usually given with food. If your dog takes Vetoryl once daily, your veterinarian may recommend giving it in the morning with a meal. This can make it easier to schedule follow-up blood tests a few hours after the dose. Give Vetoryl at about the same time each day unless your veterinarian tells you otherwise.

How long does Vetoryl stay in a dog’s system?

Trilostane is absorbed fairly quickly after a dose. Blood levels usually reach their highest point within about 1 to 2 hours and then fall over the following several hours. In healthy dogs, blood levels are generally close to baseline within about 12 hours, although this can vary from dog to dog. The effects of Vetoryl on cortisol production may not match exactly how long the medication remains measurable in the blood.

Is Vetoryl suitable for all dogs?

No. Vetoryl may not be appropriate for every dog. Extra caution or a different treatment may be needed if your dog is pregnant, is nursing puppies, has kidney disease, has liver disease, has certain electrolyte problems, or takes medications that may interact with Vetoryl. Your veterinarian will review your dog’s health history before deciding whether Vetoryl is appropriate.

How often will my dog need veterinary checkups while taking Vetoryl?

Dogs taking Vetoryl need regular veterinary monitoring. Your veterinarian may recommend blood tests and checkups shortly after treatment begins, after dose changes, and periodically during long-term treatment. These visits may include checks of cortisol response, electrolyte levels, kidney function, liver function, and your dog’s symptoms and overall health. Regular monitoring helps make sure the dose is controlling Cushing’s disease without lowering cortisol too much.

REVIEWS

Additional Information Book
Generic name:

Trilostane

Formulation:

Capsule

Strength(s):

30mg

Quantities Available:

30

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Vetoryl can I order at once from a Canadian pharmacy?

When ordering Vetoryl (trilostane) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Vetoryl is available in 30 mg capsules. The dosage can vary based on your pet’s needs, but for example, if your veterinarian prescribes 30 mg once daily, for a 90-day supply, this means you would order 90 capsules (90 days x 1 capsule per day).

Do you sell trilostane?

No, we do not sell trilostane directly, but you can still enjoy low prices on Vetoryl, which contains trilostane as an active ingredient. You will need a valid prescription from a veterinarian to purchase Vetoryl. We require this to dispense the medication safely and appropriately. You can mail, fax, or upload the prescription through your online account.

Do you offer shipping of Vetoryl (trilostane) to the United States?

Yes, we ship Vetoryl (trilostane) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Vetoryl (Trilostane). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Vetoryl (Trilostane).