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Vetoryl contains the active ingredient trilostane. It is a prescription veterinary medication used to treat Cushing’s disease in dogs.
Cushing’s disease happens when a dog’s body produces too much cortisol, a hormone made by the adrenal glands.
Vetoryl is used to treat dogs with:
Common signs of Cushing’s disease may include increased thirst, frequent urination, increased appetite, panting, hair loss, a pot-bellied appearance, and reduced energy.
Vetoryl belongs to a group of medications called adrenal steroid synthesis inhibitors.
It works by blocking an enzyme called 3β-hydroxysteroid dehydrogenase.
This reduces the amount of cortisol produced by the adrenal glands and helps bring cortisol levels closer to a healthier range.
Vetoryl helps control Cushing’s disease, but it does not cure the underlying condition.
Dogs taking Vetoryl need regular veterinary monitoring, including blood tests, to make sure cortisol levels do not become too low and that the dose remains appropriate.
Vetoryl comes as a capsule that is given by mouth.
Give Vetoryl with food, exactly as prescribed by your veterinarian.
The dose of Vetoryl depends on your dog’s:
Your veterinarian will choose the appropriate starting dose and may adjust it over time based on blood test results and your dog’s symptoms.
Do not change the dose on your own.
Try to give Vetoryl at about the same time every day.
If your dog is prescribed Vetoryl once daily, your veterinarian may recommend giving it in the morning with food so that follow-up hormone testing can be timed appropriately.
Watch your dog carefully while they are taking Vetoryl.
Contact your veterinarian promptly if you notice:
Loss of appetite, vomiting, low energy, diarrhea, and weakness are among the reported adverse effects of Vetoryl.
Dogs taking Vetoryl need regular veterinary checkups and blood tests.
Your veterinarian may monitor:
Frequent monitoring is especially important during the first few months of treatment. Follow-up testing is then usually continued periodically based on your dog’s response.
Vetoryl helps control Cushing’s disease but does not cure it.
Continue giving it for as long as your veterinarian recommends.
Do not stop treatment or change the dose unless your veterinarian tells you to.
Vetoryl (Trilostane) is available in the following forms and strength:
Vetoryl can cause side effects in some dogs.
Contact your veterinarian if your dog develops:
These symptoms may mean that cortisol levels have become too low or that your dog is having another serious reaction.
The correct Vetoryl dose is different for each dog.
Your veterinarian may change the dose based on your dog’s symptoms, blood test results, and response to treatment.
Do not increase, decrease, or skip doses unless your veterinarian tells you to.
Tell your veterinarian if your dog has kidney or liver disease.
Vetoryl may not be appropriate for some dogs with these conditions, and closer monitoring may be needed.
Vetoryl should not be used in pregnant dogs.
Tell your veterinarian if your dog is pregnant, may become pregnant, or is nursing puppies before starting treatment.
Dogs taking Vetoryl need regular veterinary monitoring.
Your veterinarian may check:
These tests help make sure the medication is working safely and that the dose remains appropriate.
Vetoryl lowers cortisol production.
If cortisol levels become too low, your dog may develop hypoadrenocorticism, also called Addison’s disease.
Signs may include severe weakness, loss of appetite, vomiting, diarrhea, dehydration, shaking, or collapse.
Seek veterinary care promptly if these symptoms occur.
Tell your veterinarian about all medications, supplements, and other products your dog receives.
Extra caution may be needed with medications such as:
Some combinations may increase the risk of high potassium levels or other side effects.
Giving too much Vetoryl can reduce cortisol to dangerously low levels.
Giving too little may not adequately control Cushing’s disease.
Give each dose exactly as prescribed and do not change the amount on your own.
Many dogs with Cushing’s disease require long-term treatment.
Because your dog’s response can change over time, regular monitoring remains important throughout treatment.
Your veterinarian may adjust the dose as your dog’s condition changes.
Give Vetoryl exactly as directed and with food.
Do not stop treatment, restart it after a break, or change the dose without speaking with your veterinarian.
Contact your veterinarian if your dog’s symptoms worsen or new symptoms develop.
Vetoryl is usually given with food. If your dog takes Vetoryl once daily, your veterinarian may recommend giving it in the morning with a meal. This can make it easier to schedule follow-up blood tests a few hours after the dose. Give Vetoryl at about the same time each day unless your veterinarian tells you otherwise.
Trilostane is absorbed fairly quickly after a dose. Blood levels usually reach their highest point within about 1 to 2 hours and then fall over the following several hours. In healthy dogs, blood levels are generally close to baseline within about 12 hours, although this can vary from dog to dog. The effects of Vetoryl on cortisol production may not match exactly how long the medication remains measurable in the blood.
No. Vetoryl may not be appropriate for every dog. Extra caution or a different treatment may be needed if your dog is pregnant, is nursing puppies, has kidney disease, has liver disease, has certain electrolyte problems, or takes medications that may interact with Vetoryl. Your veterinarian will review your dog’s health history before deciding whether Vetoryl is appropriate.
Dogs taking Vetoryl need regular veterinary monitoring. Your veterinarian may recommend blood tests and checkups shortly after treatment begins, after dose changes, and periodically during long-term treatment. These visits may include checks of cortisol response, electrolyte levels, kidney function, liver function, and your dog’s symptoms and overall health. Regular monitoring helps make sure the dose is controlling Cushing’s disease without lowering cortisol too much.
| Generic name: | Trilostane |
|---|---|
| Formulation: | Capsule |
| Strength(s): | 30mg |
| Quantities Available: | 30 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Vetoryl (trilostane) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Vetoryl is available in 30 mg capsules. The dosage can vary based on your pet’s needs, but for example, if your veterinarian prescribes 30 mg once daily, for a 90-day supply, this means you would order 90 capsules (90 days x 1 capsule per day).
No, we do not sell trilostane directly, but you can still enjoy low prices on Vetoryl, which contains trilostane as an active ingredient. You will need a valid prescription from a veterinarian to purchase Vetoryl. We require this to dispense the medication safely and appropriately. You can mail, fax, or upload the prescription through your online account.
Yes, we ship Vetoryl (trilostane) to both the United States and Puerto Rico.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Vetoryl (Trilostane). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Vetoryl (Trilostane).
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