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Polytrim is a prescription medication that contains a combination of two antibiotics, polymyxin B and trimethoprim. It is used to treat bacterial infections of the eye such as conjunctivitis and blepharitis. Polytrim works by combining two antibiotics, polymyxin B and trimethoprim, to kill bacteria.
Polymyxin B works by interfering with the bacterial cell membrane, causing it to break down, while trimethoprim blocks the bacterial enzyme dihydrofolate reductase, which is necessary for the bacteria to produce folate. By interrupting these processes, the antibiotics can kill or prevent the growth of the bacteria causing the infection. When used correctly, Polytrim can be an effective treatment for bacterial infections of the eye.
To ensure proper application of Polytrim eye drops, follow the instructions carefully. Before applying the drops, wash your hands thoroughly to avoid contamination. Do not wear contact lenses while using this medication. Tilt your head back, look upward, and pull down your lower eyelid to create a pouch. Place the dropper directly over your eye and squeeze one drop into the pouch according to your doctor’s directions. Do not touch the dropper tip or let it touch your eye or any other surface. After applying the drop, close your eyes gently and place a finger on the corner of your eye near the nose, applying gentle pressure for 1 to 2 minutes to prevent the medication from draining out.
Avoid blinking or rubbing your eye. Repeat the process with the other eye, if directed. Wait a few minutes for your vision to clear before driving or operating machinery. Do not rinse the dropper and replace the dropper cap after each use. Follow your doctor’s instructions regarding the dosage, frequency, and duration of the treatment. Do not swallow or inject the medication.
Plendil is available in the following forms and strength:
Polytrim (polymyxin B / trimethoprim) starts working right away since it is placed right where the infection is. Your symptoms should start to improve in a couple of days, so let your provider know if things are not looking better after that.
It is usually instilled once in the affected eye(s) every three hours (maximum of 6 doses in 24 hours) for 7 to 10 days. Use ophthalmic polymyxin B and trimethoprim at around the same time every day.
Polymyxin B1 and B2 were stable for 24 hours in saline (0.9%) and glucose solution (5%), however a significant degradation of polymyxin B1 and B2 was observed after 48 hours and 72 hours of assay.
| Generic name: | Polymixin/trimethoprim |
|---|---|
| Formulation: | Eye drops |
| Strength(s): | noDose |
| Quantities Available: | 10mL |
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Polytrim (Polymixin/trimethoprim). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Polytrim (Polymixin/trimethoprim).
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