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Nexlizet (bempedoic acid/ezetimibe) is a prescription medication used to help lower low-density lipoprotein (LDL) cholesterol, often referred to as “bad” cholesterol. High LDL cholesterol can contribute to the buildup of plaque in the arteries, increasing the risk of serious cardiovascular problems such as heart attack, stroke, and other forms of heart disease.
Nexlizet is typically prescribed along with a heart-healthy diet and maximally tolerated statin therapy for adults who need additional cholesterol lowering despite current treatment.
Nexlizet is used for adults with:
It is prescribed for people who require additional LDL cholesterol reduction beyond what can be achieved with diet, lifestyle changes, and statin therapy alone.
By lowering LDL cholesterol levels, Nexlizet may help reduce the progression of plaque buildup in the arteries and support long-term cardiovascular health.
Nexlizet contains two active ingredients that lower cholesterol through different mechanisms:
Bempedoic Acid
Bempedoic acid belongs to a group of medications called ATP-citrate lyase inhibitors. It works in the liver by blocking an enzyme involved in cholesterol production. This reduces the amount of cholesterol the liver makes and helps lower LDL cholesterol levels in the bloodstream.
Ezetimibe
Ezetimibe belongs to a group of medications called cholesterol absorption inhibitors. It works by reducing the amount of cholesterol absorbed from food in the small intestine, which decreases the amount of cholesterol entering the bloodstream.
Dual Cholesterol-Lowering Action
By combining these two medications into a single tablet, Nexlizet helps lower cholesterol in two ways:
This combined approach can provide greater LDL cholesterol reduction than either medication alone.
Lowering LDL cholesterol may help:
Nexlizet is most effective when used as part of a comprehensive cholesterol management plan that includes:
Continue taking Nexlizet exactly as directed, even if you feel well, since high cholesterol often causes no noticeable symptoms. Regular cholesterol testing and follow-up appointments can help your healthcare provider monitor your progress and ensure the medication is working effectively.
Nexletol is available as an oral tablet and is typically taken once daily, with or without food, as directed by your healthcare provider. To help ensure the best results, take the medication at approximately the same time each day.
High cholesterol usually does not cause noticeable symptoms, so you may not feel any different while taking Nexletol. However, it is important to continue taking the medication exactly as prescribed, even if you feel well. Stopping treatment without consulting your healthcare provider may cause your cholesterol levels to rise again.
For maximum benefit, Nexletol should be used as part of a comprehensive cholesterol management plan that includes:
Follow your healthcare provider’s recommendations regarding diet, exercise, and lifestyle changes, as these measures can help improve the effectiveness of treatment.
For most adults, the usual dose is:
Take Nexletol exactly as prescribed and do not take more or less than the recommended amount unless instructed by your healthcare provider.
Nexletol begins lowering LDL (“bad”) cholesterol after treatment starts, but it may take time before the full effects are seen. While some reduction in cholesterol levels may occur earlier, it can take up to 12 weeks to experience the full cholesterol-lowering benefit of the medication.
Your healthcare provider may schedule blood tests during treatment to monitor your cholesterol levels and assess how well the medication is working.
Regular follow-up appointments and cholesterol testing are important while taking Nexletol. These visits allow your healthcare provider to monitor your progress, evaluate your response to treatment, and make any necessary adjustments to help you achieve your cholesterol goals and support long-term cardiovascular health.
Nexletol (Bempedoic Acid) is available in the following forms and strength:Â
Before taking Nexletol, tell your healthcare provider about all of your medical conditions and all medications, vitamins, herbal products, and supplements you take. This information can help reduce the risk of side effects and potential drug interactions.
Do not take Nexletol if you are allergic to bempedoic acid or any of the ingredients in the medication.
Seek immediate medical attention if you develop signs of an allergic reaction, such as:
Nexletol may increase the risk of tendon injury, including tendon rupture. This risk may be higher in:
Contact your healthcare provider immediately if you experience:
People with liver or kidney problems may require closer monitoring while taking Nexletol. Your healthcare provider may perform blood tests during treatment to help ensure the medication remains safe and effective.
Be sure to tell your healthcare provider if you have a history of:
Nexletol may increase uric acid levels in the blood, which can trigger gout attacks in susceptible individuals.
If you have a history of gout, tell your healthcare provider before starting treatment.
Symptoms of a gout flare may include:
The safety of Nexletol during pregnancy and breastfeeding has not been fully established.
If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your healthcare provider before taking this medication.
Nexletol may interact with certain medications, supplements, and herbal products. These interactions can affect how the medication works or increase the risk of side effects.
Always provide your healthcare provider with a complete list of everything you take before starting treatment.
Some people taking Nexletol may experience muscle pain, tenderness, or weakness. In rare cases, muscle symptoms can be associated with a serious condition called rhabdomyolysis, which involves muscle breakdown and can lead to kidney damage.
Contact your healthcare provider promptly if you experience:
Nexletol is used to help lower LDL (“bad”) cholesterol levels. However, it should not replace other medications or treatments prescribed to reduce the risk of cardiovascular events such as heart attack or stroke.
Continue taking all medications prescribed by your healthcare provider and follow your recommended treatment plan.
Nexletol may cause dizziness or blurred vision in some individuals.
Until you know how the medication affects you, use caution when:
If you are planning to undergo surgery or a medical procedure, inform your healthcare provider and surgical team that you are taking Nexletol. This helps ensure that any potential medication interactions can be properly managed.
Regular monitoring and communication with your healthcare provider can help ensure that Nexletol is working effectively while minimizing the risk of potential side effects and complications.
Yes, Nexletol is often used together with other cholesterol-lowering medications, including statins and other lipid-lowering therapies. However, Nexletol may interact with certain prescription medications, over-the-counter products, vitamins, herbal supplements, and natural health products. Before starting Nexletol, provide your healthcare provider with a complete list of everything you take. This helps reduce the risk of drug interactions and ensures that your treatment plan is safe and effective.
The safety of Nexletol during pregnancy and breastfeeding has not been fully established. Because the potential effects on an unborn baby or nursing infant are not known, Nexletol should only be used during pregnancy or while breastfeeding if the potential benefits outweigh the possible risks. If you are pregnant, planning to become pregnant, or breastfeeding, discuss your treatment options with your healthcare provider before taking Nexletol.
Nexletol begins lowering LDL (“bad”) cholesterol after treatment starts, but improvements are usually gradual. Some people may begin to see changes in their cholesterol levels within a few weeks, while the full cholesterol-lowering effects may take up to 12 weeks to become apparent. Your healthcare provider may perform periodic blood tests to monitor your cholesterol levels and evaluate how well the medication is working.
People with liver or kidney problems may be able to take Nexletol, but they may require closer monitoring during treatment. Your healthcare provider may recommend periodic blood tests to assess liver and kidney function and ensure the medication remains safe for you. Be sure to inform your healthcare provider if you have a history of liver disease, kidney disease, or abnormal liver function tests before starting treatment.
The length of treatment with Nexletol varies from person to person and depends on factors such as your cholesterol levels, overall cardiovascular risk, and response to therapy. Because high cholesterol is often a long-term condition, many people take cholesterol-lowering medications for an extended period. Your healthcare provider will determine how long you should continue treatment and will regularly assess whether Nexletol remains an appropriate part of your cholesterol management plan. Even if you feel well, continue taking Nexletol as prescribed unless your healthcare provider advises otherwise. High cholesterol usually does not cause symptoms, but ongoing treatment can help reduce cholesterol levels and support long-term heart health.
| Generic name: | Bempedoic Acid/Ezetimibe, Bempedoic acid/Ezetimibe |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 180mg/10mg |
| Quantities Available: | 30, 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Nexlizet (bempedoic acid/ezetimibe) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Nexlizet is commonly prescribed as a single tablet containing bempedoic acid 180 mg and ezetimibe 10 mg, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).
Yes, we sell bempedoic acid/ezetimibe. You can enjoy low prices on this medication through our website. Please note that you will need a valid prescription from your healthcare provider to purchase bempedoic acid/ezetimibe. We require this to dispense the medication. You can mail, fax, or upload your prescription through your online account.
Yes, we ship Nexlizet (bempedoic acid/ezetimibe) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Nexlizet (Bempedoic acid/Ezetimibe). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Nexlizet (Bempedoic acid/Ezetimibe).
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