Indications
Lozol generically known as indapamide is used to treat high blood pressure and fluid retention (edema) in people with congestive heart failure. Indapamide belongs to a class of drugs known as diuretics/"water pills." It works by causing you to make more urine.
Indapamide helps prevent the body from absorbing too much salt, which can cause fluid retention. It is usually taken once a day in tablet form. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This helps your body get rid of extra salt and water. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.
Uses and Dosage
Lozol is a tablet medication that is typically taken by mouth with or without food. It is usually taken once a day in the morning and should be taken at least 4 hours before bedtime to reduce the risk of needing to urinate during the night.
If the patient also takes cholesterol-lowering drugs such as cholestyramine or colestipol, take indapamide at least 4 hours before or after taking these medications, to avoid potential interactions. Additionally, there are some precautions associated with Lozol that patients should be aware of, including the potential for allergic reactions, electrolyte imbalances, and interactions with other medications, among others.
The dosage of Lozol is based on the individual's medical condition and response to treatment.
- High blood pressure (hypertension): Start with 1.25 mg once a day in the morning. Your provider will adjust your dose based on your needs, but the most you should take is 5 mg per day.
- Swelling (edema) due to heart failure: Start with 2.5 mg once a day in the morning. Your provider will adjust your dose based on your needs, but the most you should take is 5 mg per day.
Take the medication regularly to receive the full benefits, and to take it at the same time each day to help remember when to take it. Even if the patient feels well, continue taking the medication, as high blood pressure often does not cause noticeable symptoms.
Side Effect
Common Side Effects of Lozol (Indapamide):
- Dizziness
- Fatigue, weakness, low energy
- Feeling nervous, anxious, or irritable
- Headache
- Muscle cramps or numbess in the arms or legs
- Skin rash
Serious Side Effects of Lozol (Indapamide):
- Abnormal bloodwork
- Abnormal heart rhythms
- Blurry vision
- Constipation or diarrhea
- Depression
- Difficulty sleeping
- Dry mouth
- Feeling flushed
- Feeling lightheaded or drowsy
- Having to urinate more
- Low appetitie
- Low blood pressure upon standing up
- Nausea or vomiting
- Problems with sex
- Runny nose
- Spinning sensation
- Stomach pain
- Tingling in the arms or legs
- Weight loss
Form and Strength
Lozol (Indapamide) is available in the following forms and strengths:
Indapamide: Tablet
- 1.25 mg
- 2.5 mg
Caution
- Allergic reaction: Patients with a known allergy to indapamide or sulfonamide drugs should not take Lozol.
- Electrolyte imbalance: Indapamide can cause imbalances in electrolytes such as potassium, magnesium, and sodium, especially in patients with kidney disease or other conditions that affect fluid and electrolyte balance. Blood tests may be needed to monitor electrolyte levels.
- Pre-existing medical conditions: Patients with a history of liver or kidney disease, gout, diabetes, systemic lupus erythematosus (SLE), or other medical conditions should consult with their doctor before taking Lozol.
- Pregnancy and breastfeeding: It is not recommended to take indapamide while pregnant or breastfeeding. It can cross the placenta and be present in breast milk.
- Dizziness and lightheadedness: Lozol may cause dizziness or lightheadedness, especially when first starting the medication or when getting up quickly from a sitting or lying position.
- Interactions with other medications: Patients should inform their healthcare provider of all medications, vitamins, and supplements they are taking to check for potential interactions.
- Avoid alcohol: Drinking alcohol while taking Lozol can increase the risk of dizziness and lightheadedness.
Frequently Asked Questions (FAQ)
Can Indapamide make you lose weight?
Indapamide works to get rid of extra fluid in your body. By getting rid of this fluid, it can cause weight loss. Keep in mind that this is water weight, not fat loss.
How long does it take for Indapamide to work?
Indapamide starts to work about 2 hours after you take it, but the full effect can take much longer. If you are taking it for blood pressure, your provider might adjust your dose after 4 weeks. If you are taking it for swelling or edema, your provider might adjust it after 1 week.
Can Lozol be taken while breastfeeding?
Do not take Lozol while breastfeeding, as it may pass into breast milk and harm the nursing baby. Consult with your healthcare provider to find a safe alternative.
What should I do if I miss a dose of Lozol?
If you miss a dose of Lozol, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and take the next dose at the regular scheduled time.
Can Lozol be taken with other medications?
Lozol may interact with other medications, tell your healthcare provider about all medications and supplements you are taking. This includes over-the-counter medications, herbal remedies, and vitamin supplements.
Resources
- https://www.drugs.com/cons/lozol.html
- https://www.rxlist.com/lozol-drug.htm
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/018538s028lbl.pdf
- https://www.webmd.com/drugs/2/drug-6884/lozol-oral/details
- https://www.goodrx.com/indapamide/what-is
- https://www.everydayhealth.com/drugs/indapamide
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