Before using Flovent HFA, tell your healthcare provider about all of your medical conditions, allergies, and medications. Although Flovent HFA is effective for long-term asthma control, certain health conditions may require additional monitoring during treatment.
Infections and Immune System Effects
Because Flovent HFA is a corticosteroid medication, it can affect how your immune system responds to infections. Use Flovent HFA with caution if you have:
- Active or inactive tuberculosis (TB)
- Untreated fungal infections
- Bacterial infections
- Viral infections
- Eye infections caused by herpes simplex virus
In some cases, corticosteroids may worsen existing infections or make it harder for your body to fight them. Contact your healthcare provider if you develop signs of infection such as fever, chills, persistent sore throat, or worsening respiratory symptoms.
Adrenal Gland Suppression
Flovent HFA may reduce the normal function of the adrenal glands, particularly when used at high doses or for long periods of time. The adrenal glands produce important hormones that help regulate stress responses and other body functions.
Symptoms of adrenal suppression may include:
- Extreme fatigue
- Weakness
- Dizziness
- Nausea
- Low blood pressure
Your healthcare provider may monitor you for signs of adrenal gland problems if long-term treatment is required.
Allergic Reactions
Do not use Flovent HFA if you are allergic to fluticasone propionate or any of the ingredients in the inhaler.
Although uncommon, serious allergic reactions can occur, including anaphylaxis.
Seek immediate medical attention if you experience:
- Rash or hives
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe dizziness
Bone Health
Long-term use of inhaled corticosteroids, especially at higher doses, may reduce bone mineral density and increase the risk of osteopenia or osteoporosis.
People who may be at greater risk include:
- Older adults
- Postmenopausal women
- Individuals with a family history of osteoporosis
- People with low calcium or vitamin D intake
If you have concerns about bone health, discuss them with your healthcare provider. They may recommend monitoring, lifestyle changes, or dietary supplements to help support bone strength.
Systemic Corticosteroid Effects
Although Flovent HFA acts primarily in the lungs, some of the medication may be absorbed into the bloodstream. In rare cases, especially with high doses or prolonged use, systemic corticosteroid effects can occur.
Your healthcare provider may monitor for signs of:
- Hypercorticism (excess corticosteroid exposure)
- Adrenal suppression
- Changes in growth in children and adolescents
Regular follow-up appointments can help identify and manage these effects early.
Liver Impairment and Drug Interactions
Fluticasone propionate is primarily broken down by an enzyme in the liver called CYP3A4. People with liver impairment or those taking strong CYP3A4 inhibitors may have higher levels of the medication in their body.
Examples of medications that may interact with Flovent HFA include certain:
- Antifungal medications
- HIV medications
- Antibiotics
Be sure to provide your healthcare provider with a complete list of all prescription medications, over-the-counter products, vitamins, and supplements you take.
Changes in Bone Mineral Density
Flovent HFA may contribute to changes in bone mineral density over time, particularly in individuals who are already at risk for osteoporosis or fractures. Your healthcare provider may recommend periodic monitoring if long-term treatment is necessary.
Important Safety Information
- Tell your healthcare provider if you have tuberculosis or any current or past infections.
- Inform your healthcare provider about any liver problems or medication allergies.
- Discuss any concerns about osteoporosis or bone health before starting treatment.
- Attend regular follow-up appointments and monitoring as recommended.
- Tell your healthcare provider about all medications and supplements you take.
Using Flovent HFA exactly as prescribed and maintaining regular communication with your healthcare provider can help maximize asthma control while minimizing the risk of potential side effects and complications.
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