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Cuprimine for Pet

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Cuprimine for Pet (generically known aspenicillamine) is commonly used in dogs and cats for the treatment of liver disease and Wilson's disease (a rare disorder inherited through two copies of a defective gene, one from each parent). Cuprimine is also used in aquarium treatments as a copper chelator.

Penicillamine works by binding with certain metals, such as copper, and removing them from the body. In pets, it is commonly used to treat conditions like Wilson's disease, characterized by abnormally elevated levels of copper in the body.

Use and Dosage

To use Cuprimine (penicillamine) tablets for pets, follow the dosage and administration instructions provided by your veterinarian. Cuprimine tablets are typically given orally and can be given with or without food.

The dosage of Cuprimine will vary depending on the condition of being treated and the individual pet. Your veterinarian will determine the appropriate dosage based on your pet's weight and medical history. Follow your veterinarian's instructions carefully and do not adjust the dosage without consulting them first.

For the best results, give Cuprimine at the same time(s) every day to maintain a consistent level of medication in your pet's system. If you miss a dose, give it as soon as you remember. However, if it is close to the time for your pet's next dose, skip the missed dose and continue with the regular dosing schedule. Do not give your pet a double dose of Cuprimine to make up for a missed dose.

Make sure to monitor your pet for any side effects or changes in behavior and report them to your veterinarian if they occur. Inform your veterinarian of any other medications or supplements your pet is taking as they can interact with Cuprimine.

Side Effects

Common Side Effects of Cuprimine for Pet (Penicillamine):

  • Nausea
  • Vomiting
  • Loss of appetite
  • Diarrhea
  • Rash
  • Ringing in the ears

Serious Side Effects of Cuprimine for Pet (Penicillamine):

  • Bone marrow suppression
  • Kidney damage
  • Liver damage
  • Skin reactions (such as rashes, itching, and scaling)

Forms and Strength

Cuprimine for Pet (Penicillamine) is available in the following forms and strength:

Cuprimine for Pet: Tablet

  • 250mg


  • Cuprimine can interact with other drugs and supplements your pet may be taking, inform your veterinarian of all medications and supplements your pet is taking.
  • Cuprimine has a narrow therapeutic index, which means that the safe and effective dosage range is relatively small compared to the toxic dosage range. Therefore, carefully follow the dosing instructions provided by your veterinarian.
  • Cuprimine can cause side effects such as vomiting, diarrhea, and loss of appetite, particularly when first starting treatment. If your pet experiences any adverse effects, consult your veterinarian.
  • Cuprimine can cause serious and potentially fatal side effects, such as bone marrow suppression, tissue damage, and kidney damage.
  • Cuprimine is not recommended for use in pregnant or nursing animals, as its effects on fetal and newborn animals are not well understood.
  • Cuprimine should not be used in animals with a known hypersensitivity or allergy to penicillamine or any other ingredient in the medication.
  • Cuprimine can decrease copper levels in the body, which can lead to anemia or other adverse effects. Your veterinarian will monitor your pet's copper levels during treatment and adjust the dosage as needed.
  • Cuprimine should be given with caution in animals with a history of seizures or neurological disorders, as it can worsen these conditions.
  • Cuprimine can cause immune suppression, which can increase the likelihood of infection or make infections harder to treat. Your veterinarian will monitor your pet's immune system during treatment.
  • Cuprimine should not be used in animals with certain conditions, such as systemic lupus erythematosus (SLE), rheumatoid arthritis, or myasthenia gravis, as it can exacerbate these conditions.

Frequently Asked Questions (FAQ)

How long does it take for penicillamine to start working in pets?

The onset of action of penicillamine can vary depending on the condition being treated and the individual pet. Your veterinarian can provide more specific information on what to expect.

How long does my pet need to take penicillamine?

The length of treatment with penicillamine will depend on the condition being treated. Your veterinarian will provide specific recommendations for your pet based on their individual health status and response to treatment.

Can penicillamine cure my pet's condition?

Penicillamine cannot cure certain conditions, but it can help manage symptoms and improve quality of life for some pets.

Can I give my pet penicillamine without a prescription?

No, penicillamine is a prescription medication that should only be given under the guidance and supervision of a veterinarian.


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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Cuprimine for Pet (Penicillamine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Cuprimine for Pet (Penicillamine).