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Ofev (Nintedanib) Shopper Approved

Prescription Prescription Required FormationFormulation: Soft-Gel Capsule

Ofev

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Prescription Prescription Required FormationFormulation: Soft-Gel Capsule

Nintedanib

(Generic Alternative)

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Ofev (active ingredient: nintedanib) is a prescription medication used to treat certain progressive lung diseases that can cause scarring of the lungs. It is designed to help slow the worsening of lung damage and preserve lung function over time.

Ofev belongs to a group of medications called tyrosine kinase inhibitors. It works by blocking specific proteins involved in the formation of scar tissue in the lungs. By reducing the activity of these proteins, Ofev can help slow the progression of lung fibrosis and support long-term lung health.

Idiopathic Pulmonary Fibrosis (IPF)

Ofev is used to treat idiopathic pulmonary fibrosis (IPF), a chronic lung disease that causes progressive scarring of the lung tissue. As scar tissue builds up, the lungs become stiffer and less able to transfer oxygen into the bloodstream.

People with IPF may experience symptoms such as:

  • Shortness of breath
  • Persistent dry cough
  • Fatigue
  • Reduced ability to exercise or perform daily activities

How Ofev Helps in IPF

  • Helps slow the progression of lung scarring.
  • Helps preserve lung function.
  • Supports long-term management of the disease.

Chronic Fibrosing Interstitial Lung Diseases (ILDs) with a Progressive Phenotype

Ofev is also used to treat certain chronic fibrosing interstitial lung diseases (ILDs) that continue to worsen over time despite treatment.

Interstitial lung diseases are a group of conditions that cause inflammation and scarring within the lungs. As the disease progresses, breathing may become increasingly difficult.

How Ofev Helps in Progressive ILDs

  • Slows the progression of lung fibrosis.
  • Helps preserve breathing capacity.
  • Supports long-term lung function.

Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)

Ofev is used in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD), a lung condition linked to systemic sclerosis (scleroderma).

In this condition, excessive scar tissue can develop in the lungs, leading to reduced lung function and worsening breathing symptoms.

How Ofev Helps in SSc-ILD

  • Helps slow the decline in lung function.
  • Reduces the rate of disease progression.
  • Supports long-term respiratory health.

How Ofev Works

Ofev works by blocking several proteins called growth factor receptors, which play an important role in the development of scar tissue in the lungs.

By reducing the activity of these proteins, Ofev helps slow the fibrotic process, which may help preserve lung function and delay further damage caused by progressive lung diseases.

Ofev (nintedanib) is available as an oral capsule and is typically taken twice daily, approximately 12 hours apart. To help maintain consistent levels of the medication in your body, try to take each dose at about the same times every day.

Take Ofev exactly as prescribed by your healthcare provider. Swallow the capsules whole with water. Do not crush, chew, open, or break the capsules, as this may affect how the medication works and could increase the risk of side effects.

Recommended Dosage

Adults

  • Typical recommended dose: 150 mg taken by mouth twice daily
  • Take doses approximately 12 hours apart
  • Follow the dosing schedule provided by your healthcare provider

Dose Adjustments

Some patients may require a lower dose due to side effects, changes in liver function tests, or other medical considerations. If this occurs, your healthcare provider may temporarily interrupt treatment, reduce your dose, or adjust your treatment plan.

Do not change your dose, skip doses, or stop taking Ofev without first speaking with your healthcare provider.

Taking Ofev Correctly

  • Take Ofev exactly as prescribed.
  • Swallow capsules whole with water.
  • Do not crush, chew, open, or break the capsules.
  • Take doses at about the same times each day.
  • Continue treatment unless your healthcare provider instructs you to stop.

Regular follow-up appointments and laboratory testing may be recommended while taking Ofev to help monitor your response to treatment and identify any side effects that may require dose adjustments.

Common Side Effects of Ofev (Nintedanib):

  • Abdominal pain
  • Decreased weight
  • Diarrhea
  • Fatigue
  • Liver enzyme elevation
  • Nausea
  • Skin ulcer
  • Vomiting

Serious Side Effects of Ofev (Nintedanib):

Ofev (Nintedanib) is available in the following forms and strength:

Nintedanib: Capsule

  • 100 mg
  • 150 mg

Ofev may affect liver function during treatment. In some patients, increases in liver enzymes and bilirubin levels have been reported. To help monitor your liver health, your healthcare provider will usually perform blood tests before you start treatment and periodically throughout treatment.

If significant changes in liver test results occur, your healthcare provider may temporarily reduce your dose, interrupt treatment, or discontinue Ofev if necessary. Contact your healthcare provider if you develop symptoms of liver problems, such as yellowing of the skin or eyes, dark urine, unusual tiredness, or pain in the upper right side of the abdomen.

Tell your healthcare provider if you have a history of heart disease, including coronary artery disease, or other cardiovascular conditions. Patients with a higher risk of cardiovascular problems may require closer monitoring during treatment. In some situations, your healthcare provider may recommend temporarily stopping treatment if serious cardiovascular concerns arise.

Before starting Ofev, provide your healthcare provider with a complete list of all medications you take, including prescription medications, over-the-counter products, vitamins, and herbal supplements. Drug interactions may affect how Ofev works or increase the risk of side effects.

If you are able to become pregnant, talk to your healthcare provider before starting Ofev. Nintedanib may harm an unborn baby. Effective contraception should be used during treatment and for the period recommended by your healthcare provider after treatment has ended. Contact your healthcare provider immediately if you become pregnant while taking Ofev.

Diarrhea, nausea, and vomiting are among the most common side effects of Ofev. At the first sign of these symptoms, it is important to stay well hydrated and contact your healthcare provider for advice. They may recommend medications such as anti-diarrheal treatments or anti-nausea medications to help manage symptoms.

Contact your healthcare provider promptly if you experience:

  • Severe or persistent diarrhea
  • Ongoing nausea or vomiting
  • Signs of dehydration, such as dizziness, dry mouth, or reduced urination
  • Difficulty keeping fluids down

Your healthcare provider may recommend reducing your dose, temporarily stopping treatment, or discontinuing Ofev if these side effects become severe.

If you are breastfeeding or planning to breastfeed, discuss this with your healthcare provider before taking Ofev. Because it is not known whether nintedanib passes into breast milk, you may need to either stop breastfeeding or stop taking the medication. Your healthcare provider can help you weigh the benefits and risks of each option based on your individual circumstances.

If you have any questions or concerns about Ofev, speak with your healthcare provider. Regular monitoring and open communication can help ensure that you receive the greatest benefit from treatment while minimizing potential risks.

What Is Ofev Used For?

Ofev (nintedanib) is used to treat several types of progressive lung diseases that cause scarring of the lungs. These include idiopathic pulmonary fibrosis (IPF), chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, and systemic sclerosis-associated interstitial lung disease (SSc-ILD). Ofev does not cure these conditions, but it can help slow the progression of lung scarring and preserve lung function over time.

How Does Ofev Work?

Ofev works by blocking several proteins and enzymes involved in the formation of scar tissue within the lungs. These proteins play a role in the fibrotic process that causes lung tissue to become thickened and scarred. By slowing the development of scar tissue, Ofev can help reduce the rate at which lung function declines and support long-term management of progressive lung disease.

How Is Ofev Taken?

Ofev is available as an oral capsule and is usually taken twice daily with food. The capsules should be swallowed whole with water and should not be crushed, chewed, opened, or broken. Take Ofev exactly as prescribed by your healthcare provider and try to take each dose at approximately the same times every day.

How Long Does It Take for Ofev to Work?

Ofev works gradually and may take several weeks or months before its full benefits become apparent. Because Ofev is designed to slow disease progression rather than provide immediate symptom relief, you may not notice an immediate improvement in how you feel. It is important to continue taking Ofev as prescribed, even if you do not notice immediate changes. Regular follow-up appointments and lung function tests can help your healthcare provider monitor how well the treatment is working.

What Should I Do If I Miss a Dose of Ofev?

If you miss a dose of Ofev, skip the missed dose and take your next dose at the regular scheduled time. Do not take two doses at the same time or take an extra dose to make up for a missed dose. Taking more than the prescribed amount may increase the risk of side effects without improving the effectiveness of the medication. If you frequently miss doses or have questions about your dosing schedule, speak with your healthcare provider or pharmacist for guidance.

REVIEWS

Additional Information Book
Generic name:

Nintedanib

Formulation:

Soft-Gel Capsule

Strength(s):

100mg, 150mg

Quantities Available:

60, 120, 180

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Ofev can I order at once from a Canadian pharmacy?

When ordering Ofev (nintedanib) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Ofev is commonly prescribed in dosages of 100 mg or 150 mg, taken orally twice daily. For a 90-day supply, this means you would order, 180 capsules (90 days x 2 capsules per day).

Do you sell nintedanib?

Yes, we sell nintedanib. You can enjoy low prices on this medication through our website. To place an order, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication. You can mail, fax, or upload your prescription through your online account for convenience.

Do you offer shipping of Ofev (nintedanib) to the United States?

Yes, we ship Ofev (nintedanib) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Ofev (Nintedanib). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Ofev (Nintedanib).