Proloprim (Trimethoprim)

Indications

Proloprim is a prescription medication used to treat bacterial infections, including infections of the urinary tract. It contains the active ingredient trimethoprim. It belongs to a group of drugs called antibiotics. It works by stopping the growth and multiplication of bacteria, allowing the immune system to fight off the infection.

Trimethoprim is administered in combination with other medications to treat certain types of pneumonia and eliminate bacteria that cause urinary tract infections. It is also used for the treatment of traveler's diarrhea. However, note that antibiotics, including Trimethoprim, are not effective against viral infections such as colds, flu, or other viral infections.

Use and Dosage

Trimethoprim is available as an oral tablet and can be taken with or without food. Typically, it is taken once or twice a day, as per doctor's instructions. Carefully follow the directions on the prescription label and seek clarification from the doctor or pharmacist if any part is unclear. Trimethoprim should be taken exactly as directed, and it is advised not to take more or less of it or take it more often than prescribed by the doctor.

The recommended dosages of Trimethoprim depend on the medical condition being treated, the patient's age, and other factors. The recommended dosages of Trimethoprim for adults vary depending on the medical condition being treated and can range from 100 milligrams every 12 hours to 800 milligrams once a day. For children 2 months of age and older, the dose is usually based on body weight and is determined by the doctor.

Follow the doctor's instructions carefully and do not take more or less Trimethoprim, or more often than prescribed. If you have any questions about the correct dosage of Trimethoprim, you should consult your doctor or pharmacist.

Side Effects

Common Side Effects of Proloprim (Trimethoprim):

• Changes in taste
• Diarrhea
• Fever
• Headache
• Itching and rash
• Loss of appetite
• Nausea
• Skin sensitivity to sunlight
• Stomach upset
• Swollen tongue
• Vomiting

Serious Side Effects of Proloprim (Trimethoprim):

• Bluish-colored fingernails, lips, or skin
• Difficulty breathing or swallowing
• Fever or chills
• Itching
• Joint aches
• Mouth sores
• Paleness
• Rash (hives)
• Sore throat
• Unusual bruising or bleeding
• Yellowing of the skin or eyes

Forms and Strength

Proloprim (Trimethoprim) is available in the following forms and strength:

Trimethoprim: Scored Tablet

• 100 mg
• 200 mg

Cautions

• Allergic reactions: People who are allergic to trimethoprim or other sulfa drugs should avoid taking Proloprim.
• Blood disorders: Proloprim may cause changes in blood cell counts, which can lead to anemia, thrombocytopenia, or other blood disorders.
• Liver and kidney function: Proloprim may affect the function of the liver and kidneys, especially in people who have preexisting liver or kidney disease.
• Pregnancy and breastfeeding: Proloprim should not be used during pregnancy, especially during the first trimester, unless the benefits outweigh the risks. It may also be excreted in breast milk, so it should be used with caution in breastfeeding mothers.
• Interactions with other drugs: Proloprim may interact with other medications, including blood thinners, diuretics, and some cancer drugs. Inform your healthcare provider of all medications you are taking before starting Proloprim.
• Folate deficiency: Proloprim can interfere with the body's ability to use folate, which is important for red blood cell production and other functions. This can lead to folate deficiency, especially in people who are already at risk, including pregnant women and older adults.
• Sun sensitivity: Proloprim may make the skin more sensitive to sunlight, which can lead to sunburn or skin rash. Patients should avoid prolonged exposure to sunlight or UV radiation.
• G6PD deficiency: Proloprim may cause hemolysis (breakdown of red blood cells) in people with a genetic condition called glucose-6-phosphate dehydrogenase (G6PD) deficiency.
• Neurologic effects: Rarely, Proloprim may cause neurologic side effects, such as convulsions, tremors, and hallucinations.

Frequently Asked Questions (FAQ)

How long does it take Proloprim to work?

Proloprim can start working within a few hours, but it may take up to a few days for symptoms to improve. Patients should continue taking the medication for the duration prescribed by their healthcare provider to ensure that the infection is fully treated.

Can Proloprim be taken with food?

Proloprim can be taken with or without food. Patients should follow the instructions of their healthcare provider for the best way to take the medication.

What should I do if I miss a dose of Proloprim?

If a dose of Proloprim is missed, patients should take it as soon as possible. However, if it is almost time for the next dose, they should skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed dose.

Can Proloprim cause diarrhea?

Yes, diarrhea is a possible side effect of Proloprim. Patients should let their healthcare provider know if they experience severe or persistent diarrhea while taking the medication.

Resources

• https://medlineplus.gov/druginfo/meds/a684025.html
• https://www.rxlist.com/trimethoprim-drug.htm
• https://www.webmd.com/drugs/2/drug-4083/trimethoprim-oral/details
• https://discountdrugsfromcanada.com/proloprim-trimethoprim.html
• https://www.webmd.com/drugs/2/drug-1369/proloprim-oral/details
• https://www.drugs.com/cdi/proloprim.html