Livial (Tibolone)

Indications

Livial is used to relieve menopausal symptoms such as hot flashes, vaginal dryness, and mood swings, as well as to prevent bone loss and reduce the risk of fractures. It contains active ingriedent called tibolone.

Tibolone is a synthetic steroid hormone used for hormone replacement therapy (HRT) in postmenopausal women. Unlike other forms of HRT that contain actual hormones, such as estrogen and progestogen, Livial works by mimicking the effects of these hormones in the body.

Use and Dosage

Livial comes in tablet form and should be taken exactly as prescribed by your doctor. Swallow the tablet whole with a drink of water; do not chew, crush, or break it. You may take Livial with or without food but take it at the same time each day to maintain consistent levels of the medication in your body.

The Livial pack contains 28 white tablets. The strips with Livial are marked with the days of the week. Start by taking the tablet marked with that day. For example, if it is a Monday, take a tablet marked Monday on the upper row of the strip. Follow the days of the week until the strip is empty. Start the next strip the next day.

If you miss a dose of Livial, take it as soon as you remember unless it has been more than 12 hours since your last dose. If it has been more than 12 hours, skip the missed dose and take your next tablet at the usual time. Do not take two tablets together to make up for a missed dose.

Side Effects

Common Side Effects of Livial (Tibolone):

• Abnormal hair growth
• Breast pain
• Breast tenderness
• Cervical thickening
• Endometrial hyperplasia
• Genital itching
• Lower abdominal pain
• Pelvic pain
• Vaginal bleeding
• Vaginal discharge
• Weight gain

Serious Side Effects of Livial (Tibolone):

• Changes in liver function
• Depression
• Dizziness
• Fluid retention
• Gastro-intestinal upset
• Headache
• Joint pain
• Migraine
• Muscle pain
• Probable memory loss
• Rash or itching
• Stroke
• Visual disturbances

Forms and Strength

Livial (Tibolone) is available in the following forms and strength:

Livial: Tablet

• 2.5mg

Tibolone: Tablet

• 2.5mg

Cautions

• Livial has been associated with an increased risk of breast cancer recurrence compared to placebo. Women with a personal or family history of breast cancer may need to avoid or
• Tibolone may increase the risk of developing endometrial cancer (cancer of the lining of the uterus), especially in women who still have a uterus. Women who have not had a hysterectomy should talk to their doctor about the risks of taking Livial.
• Livial may increase the risk of developing blood clots, which can lead to serious health problems like stroke or heart attack. Women with a history of blood clots, as well as those who are overweight, smoke, or have other risk factors for blood clots, should talk to their doctor about the risks of taking Livial.
• Livial may cause abnormal vaginal bleeding or spotting. Women who experience any unusual vaginal bleeding while taking Livial should contact their doctor.
• Like any medication, Livial may cause side effects like headaches, weight gain, or mood changes. Women who experience any unexpected or concerning side effects while taking Livial should talk to their doctor.
• Tibolone may cause liver damage in women. Patients with a history of liver disease and those who experience symptoms such as yellowing of the skin or eyes while taking Livial should seek medical attention immediately.
• Tibolone may increase the risk of stroke or other cardiovascular events. Women with a history of heart disease or stroke, as well as those who have high blood pressure or high cholesterol, should talk to their doctor about the risks and benefits of taking Livial.
• Tibolone may interact with other medications, including some antibiotics and antifungal agents. Women who are taking other medications should talk to their doctor or pharmacist about potential interactions before taking Livial.
• Livial is not recommended for use during pregnancy or while breastfeeding.
• Tibolone is not recommended for use in premenopausal women, as it may disrupt normal menstrual cycles and lead to irregular bleeding.
• Tibolone may worsen certain conditions, such as migraines, epilepsy, and asthma.

Frequently Asked Questions (FAQ)

How long does it take for Livial to start working?

Livial may take several weeks to start working, and the full benefits may not be seen for several months.

Can Livial be used for contraception?

No, Livial is not a contraceptive and should not be used as a form of birth control.

How should I store Livial?

Livial should be stored in a cool, dry place away from direct heat and sunlight. Keep the tablets in their original packaging until you are ready to take them.

What should I do if I miss a dose of Livial?

If you miss a dose of Livial, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose at your regular time. Do not take a double dose of Livial.

Resources

• https://www.drugs.com/uk/livial-2-5mg-tablets-leaflet.html
• https://www.news-medical.net/drugs/Livial.aspx
• https://patient.info/medicine/tibolone-tablets-livial
• https://www.healthdirect.gov.au/medicines/brand/amt,39758011000036104/livial
• https://www.1mg.com/drugs/livial-tablet-36729?wpsrc=Google+Organic+Search