Glipizide is prescribed to treat noninsulin-dependent (Type 2) diabetes mellitus (NIDDM) along with diet, exercise, and insulin therapy, if necessary.
Type 2 diabetes is far more common than Type 1, affecting between 90 percent and 95 percent of people with diabetes over age 20. It occurs when your body is resistant to the effects of insulin or your pancreas produces some, but not enough, insulin to maintain a normal glucose level.
- Treatment with glipizide may increase the risk of death from cardiovascular disease compared to treatment of diabetes with diet alone or diet plus insulin. Discuss with your doctor the risks and benefits of treatment with this medicine.
- Follow diet, medication, and exercise routines closely.
- Avoid alcohol as it may lower blood sugar and may interfere with your diabetes treatment.
- While taking this medicine, check your blood and urine sugar periodically for abnormal levels.
Before taking glipizide, tell your doctor if you
- have kidney disease;
- have liver disease;
- have thyroid disease;
- have Type 1 diabetes mellitus (insulin-dependent diabetes);
- have a serious infection, illness, or injury;
- need surgery;
- are pregnant, planning to become pregnant or breastfeeding.
Glipizide Side Effects
Most severe: Coma, disorientation, pale skin, seizures, shallow breathing.
Most common: Constipation, diarrhea, dizziness, drowsiness, gas, headache, hives, itching, low blood sugar, nervousness, sensitivity to light, skin rash and eruptions, stomach pain, tremor.
Other: Anemia and other blood disorders, yellow eyes and skin.
This information is advisory only. It does not contain all information about this medication. If you have any questions about glipizide, ask your doctor, pharmacist, or health care provider.
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