Tuesday, August 08, 2006

Celebrex for arthritis.

What is Celebrex taken for?


Often prescribed for the relief of joint pain, swelling and stiffness of osteoarthritis and rheumatoid arthritis, Celebrex is also taken for:

  • management of acute pain in adults from strains and sprains or pain after surgery
  • painful menstrual cramps
  • relief of the signs and symptoms of ankylosing spondylitis (form of arthritis that mainly effects the spine) - usually found in young adults, it can cause inflammation, pain and stiffness in the shoulders, knees, hips, ribs, and feet



How does Celebrex work to relieve arthritis pain?


Celebrex works to relieve arthritis pain by targeting an enzyme found in the body called COX-2. This enzyme plays a key role in causing both pain and inflammation in your joints. Celebrex is not a cure for arthritis pain and like other medicines it may not work for everyone. If you want the best results be sure to follow your doctor's instructions.



What is arthritis?


The term arthritis means "joint inflammation." Arthritis is a complex disorder that includes more than 100 different conditions and can affect people at any stage of life. The two most common types of arthritis are osteoarthritis and rheumatoid arthritis.


Osteoarthritis begins with the breakdown of joint cartilage, leading to pain and stiffness and commonly affects the joints of the fingers, knees, hips, and spine. Work-related repetitive injury and physical trauma may contribute to the development of osteoarthritis. For example, if you have a strenuous job that requires repetitive bending, kneeling, or squatting you may be at high risk for osteoarthritis of the knee.



Rheumatoid arthritis can affect numerous joints and, in some cases, other parts of the body, including the blood, the lungs, and the heart. Pain occurs when the joint lining becomes inflammed which can cause stiffness, swelling, warmth and redness. The affected joint may also lose its shape, resulting in loss of normal movement. Rheumatoid arthritis can last a long time and can be a disease of many symptoms and few to no symptoms.



Who should not take Celebrex?


Celebrex should not be used if you:

  • have had allergic reactions to certain drugs called sulfonamides
  • have experienced asthma, hives, or allergic reactions after taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs)
  • are in late pregnancy
  • are breast-feeding
  • are having or have recently had a certain kind of heart surgery called coronary artery bypass graft



Does Celebrex have any side effects?


Generally well tolerated, Celebrex has been known to have these side effects:

  • indigestion
  • diarrhea
  • abdominal pain



The chance of serious heart problems, such as heart attacks or strokes may increase while taking Celebrex. Serious skin reactions or stomach and intestine problems, such as bleeding and ulcers, can occur without warning and may cause death.



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